Sound waves vs. tremors: new registry tracks Long-Term results
NCT ID NCT04991831
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This registry follows 50 people with tremor-dominant Parkinson's disease who have undergone a focused ultrasound thalamotomy. The procedure uses sound waves to target a small area in the brain that causes tremors. The goal is to collect long-term safety data and measure how well the treatment controls tremors over time.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- focused ultrasound (Exablate Neuro system)
- What this could lead to
- If successful, this could confirm that focused ultrasound thalamotomy is a safe and effective long-term option for controlling severe tremors in Parkinson's disease.
- What could go wrong
- This is an observational registry, not a controlled trial, so it cannot prove the treatment works better than alternatives. Long-term side effects or loss of tremor control are possible.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Email: •••••@•••••
Locations
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Brigham and Women's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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Miami Neuroscience Institute Baptist Health
RECRUITINGMiami, Florida, 33176, United States
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Miami Valley Hospital
RECRUITINGFairborn, Ohio, 45324, United States
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Novant Health Brain & Spine Surgery
RECRUITINGHuntsville, North Carolina, 28708, United States
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Rush University
RECRUITINGChicago, Illinois, 60612, United States
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University of Dundee
RECRUITINGDundee, Scotland, DD1 9SY, United Kingdom
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Weill Cornell Medicine
RECRUITINGNew York, New York, 10065, United States
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