Insightec
Clinical trials sponsored by Insightec, explained in plain language.
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Sound waves target Parkinson's brain without surgery
Disease control CompletedThis study tested whether focused ultrasound could safely reduce Parkinson's disease motor symptoms like tremor and stiffness. Thirty-six participants with one-sided symptoms were randomly assigned to receive either the real ultrasound treatment or a sham procedure. Researchers c…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Sound waves open Brain's defenses to attack deadly tumors
Disease control CompletedThis study tested whether a focused ultrasound device called ExAblate could safely and temporarily open the blood-brain barrier—a natural protective layer—in patients with aggressive brain tumors (glioblastoma). The goal was to see if opening this barrier could help standard chem…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 31, 2026 12:12 UTC
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Sound waves open Brain's shield to attack deadly tumor
Disease control CompletedThis study tested whether a special focused ultrasound device could safely and temporarily open the protective blood-brain barrier in people with recurrent glioblastoma, a very aggressive brain cancer. The goal was to see if opening this barrier would help the chemotherapy drug c…
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Mar 31, 2026 12:11 UTC
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Ultrasound opens Brain's door for Parkinson's drug
Disease control CompletedThis small, early-stage study tested a new method to get medicine into the brain for Parkinson's disease. Researchers used focused ultrasound guided by an MRI to temporarily open the brain's protective barrier in four patients. They delivered a drug called Cerezyme three times to…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 30, 2026 14:33 UTC
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Sound waves used to open Brain's protective barrier for cancer treatment
Disease control CompletedThis small study tested whether using focused ultrasound to temporarily open the blood-brain barrier is safe and possible. The barrier normally protects the brain but can block cancer drugs. Eight patients with breast cancer that had spread to the brain received the ultrasound tr…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 30, 2026 14:31 UTC
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Sound waves target Parkinson's brain without surgery
Disease control CompletedThis small study tested whether focused ultrasound waves could safely treat Parkinson's disease movement problems without surgery. Six people who had already received one-sided brain treatment received the same treatment on the other side. Researchers measured whether this non-in…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 30, 2026 14:30 UTC
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Ultrasound breaks through Brain's defenses in Alzheimer's fight
Disease control CompletedThis study tested whether using focused ultrasound waves could safely open the blood-brain barrier in people with Alzheimer's disease. Thirty-five participants received three ultrasound treatments aimed at specific brain areas, with researchers monitoring safety and looking for c…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Mar 30, 2026 14:29 UTC
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Sound waves open Brain's defenses to fight cancer
Disease control CompletedThis study tested a device that uses focused sound waves to temporarily open the protective blood-brain barrier. The goal was to see if this safe procedure could help standard chemotherapy drugs reach brain tumors more effectively in patients with glioblastoma. Researchers enroll…
Sponsor: InSightec • Aim: Disease control
Last updated Mar 25, 2026 14:09 UTC
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Ultrasound 'Key' unlocks brain for chemo in tumor fight
Disease control CompletedThis study tested a new approach for treating recurrent glioblastoma, an aggressive brain cancer. Researchers used a focused ultrasound device to temporarily open the protective blood-brain barrier, aiming to help the chemotherapy drug carboplatin reach the tumor more effectively…
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Mar 06, 2026 15:37 UTC
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Sound waves target Parkinson's shaking in new trial
Symptom relief CompletedThis small study tested whether a non-invasive, focused ultrasound procedure could safely reduce severe hand and arm tremor in people with Parkinson's disease whose shaking doesn't respond well to medication. Ten participants had ultrasound waves precisely aimed at a small area i…
Phase: NA • Sponsor: InSightec • Aim: Symptom relief
Last updated Mar 30, 2026 14:35 UTC
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Sound waves target brain to calm uncontrollable shaking
Symptom relief CompletedThis study tested a focused ultrasound procedure to reduce shaking in both hands for people with essential tremor who don't get enough relief from medication. It involved treating one side of the brain, waiting at least nine months, then treating the other side. The goal was to s…
Phase: NA • Sponsor: InSightec • Aim: Symptom relief
Last updated Mar 30, 2026 14:29 UTC
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Scientists test ultrasound to penetrate brain barrier in ALS patients
Knowledge-focused CompletedThis small study tested whether focused ultrasound could safely and temporarily open the blood-brain barrier in people with ALS. The blood-brain barrier normally protects the brain but can block potential treatments. Researchers wanted to see if this technique was feasible and sa…
Phase: NA • Sponsor: InSightec • Aim: Knowledge-focused
Last updated Apr 01, 2026 14:42 UTC
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Scientists test ultrasound to open brain barrier in Parkinson's dementia
Knowledge-focused CompletedThis study tested whether a special type of focused ultrasound could safely and temporarily open the blood-brain barrier in people with mild to moderate Parkinson's disease dementia. The blood-brain barrier protects the brain but can also block helpful treatments. Researchers wan…
Phase: NA • Sponsor: InSightec • Aim: Knowledge-focused
Last updated Mar 24, 2026 12:09 UTC