Insightec
Clinical trials sponsored by Insightec, explained in plain language.
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Sound waves zapped brain to stop Parkinson's shakes
Disease control CompletedThis study tested a device that uses focused ultrasound to create a small burn in a brain area linked to tremors. It included 26 people with Parkinson's disease whose tremors did not improve with medication. The goal was to see if the procedure is safe and reduces shaking.
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 14:02 UTC
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Sound waves vs. Parkinson's: tiny trial tests brain zapping
Disease control CompletedThis small safety trial tested a device called ExAblate that uses focused ultrasound to create a tiny lesion in the brain area linked to Parkinson's motor symptoms. Seven people with advanced Parkinson's took part to see if the procedure is safe and might improve movement. The go…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 12:10 UTC
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Sound waves help chemo reach brain tumors in early trial
Disease control CompletedThis small study tested whether a device using focused ultrasound can safely open the blood-brain barrier in patients with high-grade glioma (a type of aggressive brain cancer). The goal was to allow standard chemotherapy to reach the tumor more effectively. Only 3 patients were …
Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 12:08 UTC
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Sound waves vs. Parkinson's: new ultrasound treatment shows promise
Disease control CompletedThis study tested a device called ExAblate that uses focused ultrasound to create a tiny lesion in the brain area causing Parkinson's motor problems. 36 participants were randomly assigned to receive the real treatment or a sham (fake) procedure. The goal was to see if the treatm…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 12:00 UTC
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Sound waves aimed at brain may ease Parkinson's tremors
Disease control CompletedThis small study tested whether a device that uses focused ultrasound (sound waves) can safely improve movement problems in people with Parkinson's disease. Six participants who already had one side treated received the second side. The goal was to check safety and see if symptom…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC
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Ultrasound zaps tremors in both hands: tiny trial shows promise
Disease control CompletedThis study tested a device called ExAblate that uses focused ultrasound to treat severe hand tremors from essential tremor. Seven people who had already been treated on one side received a second treatment on the other side at least 9 months later. The goal was to see if it was s…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:04 UTC
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Ultrasound opens brain barrier to deliver Parkinson's drug in tiny trial
Disease control CompletedThis pilot study tested whether a focused ultrasound device could temporarily open the blood-brain barrier to deliver the drug Cerezyme into the brains of 4 people with Parkinson's disease. The main goal was to see if the procedure was safe and could successfully get the drug int…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Sound waves open Brain's shield to attack deadly tumors
Disease control CompletedThis study tested a device that uses sound waves and tiny bubbles to temporarily open the blood-brain barrier in 28 people with recurrent glioblastoma, a type of brain cancer. The goal was to see if it is safe and feasible to let the chemotherapy drug carboplatin reach the tumor …
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Sound waves may help deliver cancer drugs to the brain
Disease control CompletedThis study tested whether a device that uses focused ultrasound can safely and temporarily open the blood-brain barrier in people with HER2-positive breast cancer that has spread to the brain. Eight participants received the procedure, and researchers checked for side effects and…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Sound waves open brain barrier to attack tumors
Disease control CompletedThis study tested whether a device called ExAblate, which uses focused ultrasound, can safely open the blood-brain barrier in 20 people with high-grade glioma (a type of brain cancer). The goal was to allow standard chemotherapy to reach the tumor more effectively. Researchers ch…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 11:03 UTC
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Sound waves open brain's shield to attack deadly tumors
Disease control CompletedThis early-phase study tested whether a focused ultrasound device can safely open the blood-brain barrier in 13 adults with recurrent glioblastoma, a severe brain cancer. The goal was to let the chemotherapy drug carboplatin reach the tumor more effectively. The study focused on …
Phase: PHASE1, PHASE2 • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 08:13 UTC
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Sound waves may help Alzheimer's drugs reach the brain
Disease control CompletedThis study tested a device that uses focused ultrasound to temporarily open the blood-brain barrier in 35 people with Alzheimer's disease. The goal was to see if this procedure is safe and could help treatments reach the brain more effectively. Participants were between 50 and 85…
Phase: NA • Sponsor: InSightec • Aim: Disease control
Last updated Jun 27, 2026 08:12 UTC
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Ultrasound zaps brain barrier in Parkinson's dementia – first safety results in
Knowledge-focused CompletedThis study tested whether a focused ultrasound device can safely and temporarily open the blood-brain barrier in 20 people with mild-to-moderate Parkinson's disease dementia. The goal was to see if the procedure is safe and feasible, not to treat the disease itself. Researchers m…
Phase: NA • Sponsor: InSightec • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC
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Ultrasound breakthrough: could opening the Brain's barrier help ALS?
Knowledge-focused CompletedThis early study tested whether a special ultrasound technique could safely open the blood-brain barrier in the motor area of the brain in 4 people with ALS. The goal was to see if the procedure was safe and possible, not to treat the disease. Researchers measured side effects an…
Phase: NA • Sponsor: InSightec • Aim: Knowledge-focused
Last updated Jun 27, 2026 11:03 UTC