Sound waves open brain's shield to attack deadly tumors
NCT ID NCT04440358
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tested whether a focused ultrasound device can safely open the blood-brain barrier in 13 adults with recurrent glioblastoma, a severe brain cancer. The goal was to let the chemotherapy drug carboplatin reach the tumor more effectively. The study focused on safety and whether the barrier could be opened, not on curing the disease.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Fondazione IRCCS Neurologico Carlo Besta
Milan, 20133, Italy
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Sunnybrook Health Sciences Centre
Toronto, Ontario, M4N 3M5, Canada
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Yonsei University Medical Center
Seoul, 120-752, South Korea
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Other studies related to the condition(s) this trial covers.
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