Ultrasound breakthrough: could opening the Brain's barrier help ALS?

NCT ID NCT03321487

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early study tested whether a special ultrasound technique could safely open the blood-brain barrier in the motor area of the brain in 4 people with ALS. The goal was to see if the procedure was safe and possible, not to treat the disease. Researchers measured side effects and used MRI scans to check if the barrier opened and then closed again.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Sunnybrook Health Sciences Centre

    Toronto, Ontario, M4N 3M5, Canada

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