Sound waves vs. Parkinson's: tiny trial tests brain zapping
NCT ID NCT02246374
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This small safety trial tested a device called ExAblate that uses focused ultrasound to create a tiny lesion in the brain area linked to Parkinson's motor symptoms. Seven people with advanced Parkinson's took part to see if the procedure is safe and might improve movement. The goal was to check for side effects and measure changes in motor function over four months.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
focused ultrasound (ExAblate Transcranial System)
What this could lead to
If successful, this could point toward a non-invasive treatment option for Parkinson's motor symptoms, reducing the need for medication or surgery.
What could go wrong
This is a very early feasibility trial with only 7 participants, focused on safety. It may not lead to a widely available treatment, and risks include side effects from brain lesioning.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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University of Virginia
Charlottesville, Virginia, 22908, United States