Sound waves vs. Parkinson's: new ultrasound treatment shows promise
NCT ID NCT03454425
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a device called ExAblate that uses focused ultrasound to create a tiny lesion in the brain area causing Parkinson's motor problems. 36 participants were randomly assigned to receive the real treatment or a sham (fake) procedure. The goal was to see if the treatment safely improves movement on the more affected side of the body.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ExAblate subthalamotomy (focused ultrasound device)
What this could lead to
If it works, this could offer a non-invasive option to reduce Parkinson's motor symptoms without surgery or implants.
What could go wrong
This is a small, early-stage trial with only 36 participants. The sham control may reveal limited benefit, and risks include side effects from brain lesioning.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Hospital Universitario HM Puerta Del Sur. CINAC
Móstoles, Madrid, 28938, Spain