Sound waves may help cancer drugs reach the brain
NCT ID NCT05317858
First seen Jun 27, 2026 · Last updated Jul 23, 2026 · Updated 2 times
Summary
This study tests whether a focused ultrasound device can safely open the blood-brain barrier in people with non-small cell lung cancer that has spread to the brain. About 30 participants will receive standard immunotherapy plus the ultrasound procedure. The goal is to see if this helps the drugs work better against brain tumors.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Atrium Health Wake Forest Baptist
RECRUITINGWinston-Salem, North Carolina, 27103, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Hoag Memorial Hospital Presbyterian
RECRUITINGNewport Beach, California, 92663, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Johnston Willis Hospital
RECRUITINGRichmond, Virginia, 23235, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Miami Cancer Institute at Baptist Health
RECRUITINGMiami, Florida, 33176, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Oregon Health & Science University
RECRUITINGPortland, Oregon, 97239, United States
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Rhode Island Hospital
RECRUITINGProvidence, Rhode Island, 02903, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Samsung Medical Center
NOT_YET_RECRUITINGSeoul, Seoul, 06351, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Seoul National University Hospital
NOT_YET_RECRUITINGSeoul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Severance Hospital, Yonsei University Health System
NOT_YET_RECRUITINGSoeul, South Korea
Contact Phone: •••-•••-•••• Email: •••••@•••••
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St. Joseph's Hospital and Medical Center
NOT_YET_RECRUITINGPhoenix, Arizona, 85013, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Sunnybrook Research Institute
COMPLETEDToronto, Ontario, M4N 3M5, Canada
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University of Maryland
RECRUITINGBaltimore, Maryland, 21201, United States
Contact
Contact
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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