Sound waves help chemo reach brain tumors in early trial
NCT ID NCT04998864
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This small study tested whether a device using focused ultrasound can safely open the blood-brain barrier in patients with high-grade glioma (a type of aggressive brain cancer). The goal was to allow standard chemotherapy to reach the tumor more effectively. Only 3 patients were enrolled, and the study focused on safety and whether the barrier could be opened repeatedly. This is not a cure, but a way to improve existing treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CINAC-Hospital HM Puerta del Sur
Móstoles, Madrid, 28938, Spain
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Fondazione IRCCS Neurologico Carlo Besta
Milan, 20133, Italy
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