Sound waves help chemo reach brain tumors in early trial

NCT ID NCT04998864

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This small study tested whether a device using focused ultrasound can safely open the blood-brain barrier in patients with high-grade glioma (a type of aggressive brain cancer). The goal was to allow standard chemotherapy to reach the tumor more effectively. Only 3 patients were enrolled, and the study focused on safety and whether the barrier could be opened repeatedly. This is not a cure, but a way to improve existing treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for GLIOBLASTOMA are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • CINAC-Hospital HM Puerta del Sur

    Móstoles, Madrid, 28938, Spain

  • Fondazione IRCCS Neurologico Carlo Besta

    Milan, 20133, Italy

More trials for these conditions

Other studies related to the condition(s) this trial covers.