Sound waves zapped brain to stop Parkinson's shakes

NCT ID NCT04002596

Completed Disease control Sponsor: InSightec Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a device that uses focused ultrasound to create a small burn in a brain area linked to tremors. It included 26 people with Parkinson's disease whose tremors did not improve with medication. The goal was to see if the procedure is safe and reduces shaking.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: focused ultrasound (ExAblate Neuro device)
What this could lead to: If it works, this could offer a non-invasive option to reduce severe tremors in Parkinson's patients who don't respond well to medication.
What could go wrong: This was a small, early feasibility study with only 26 participants. The procedure may not work for everyone and carries risks like side effects from brain tissue ablation.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Parkinson disease

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

PARKINSON DISEASE

Contacts and locations

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Locations

Henan Provincial People's Hospital

Zhengzhou, Henan, 450003, China
Shonan Fujisawa Tokushukai Hospital

Fujisawa, Kanagawa, Japan

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