Chinese Pla General Hospital

This study looked at whether giving a steroid called methylprednisolone during surgery could help prevent post-operative delirium, a common state of confusion, in elderly patients having abdominal operations. Researchers analyzed medical records from over 25,800 patients aged 65 …

This study tested whether a personalized dose of a drug called ATG works better than a standard fixed dose for patients receiving a stem cell transplant from a half-matched donor. The goal was to find the dose that best prevents a dangerous complication where the donor cells atta…

This study looked at whether medications commonly used for enlarged prostate (BPH) might also help reduce the risk of heart disease. Researchers analyzed health records from 10,000 men with BPH to see if those taking 5-alpha reductase inhibitors had fewer heart problems. The goal…

This study tested whether a new 3D surgical navigation system could help surgeons perform a specific prostate surgery (HoLEP) more precisely. The system combined MRI scans and real-time ultrasound to create a live map of the prostate during the operation. Researchers compared 150…

This study tested whether adding the drug venetoclax to a specific chemotherapy regimen (CACAG) works better than the standard '3+7' chemotherapy for people newly diagnosed with acute myeloid leukemia (AML). It involved 200 participants aged 14-75 and aimed to see if the new comb…

This study looked at whether a drug called trimetazidine could reduce permanent scarring in the heart after a major heart attack (STEMI). Researchers observed 194 patients who had received standard emergency treatment to open their blocked artery. They used heart scans to measure…

This study tested whether a single dose of esketamine, a drug related to the anesthetic ketamine, could help reduce anxiety and depression in patients before and after heart valve surgery. Researchers enrolled 142 adults undergoing this major surgery to see if the treatment impro…

This study tested whether giving a sedative called dexmedetomidine during surgery could help prevent delirium, a serious state of confusion, in patients aged 65 and older having major abdominal operations. Researchers compared the drug to a placebo (saltwater) in 268 patients acr…

This study analyzed data from 8,751 patients aged 65+ who had elective surgery to understand how their health before surgery relates to complications afterward. Researchers looked at different assessment tools to see which ones best predict heart and stroke problems within 30 day…

This study followed 6,196 adults aged 65+ having non-emergency surgery to understand how post-surgery confusion (delirium) affects physical frailty and survival. Researchers tracked patients' strength and health before surgery, checked for confusion after surgery, and followed up…

This study examined how aging affects brain activity during anesthesia. Researchers recorded brain signals from 47 patients aged 19-82 during surgery to understand how older brains respond differently to anesthesia drugs. The goal is to improve anesthesia safety for elderly patie…

This study looked at whether having long-term pain before joint replacement surgery makes older adults more likely to feel depressed after the operation. Researchers analyzed health records from 575 patients aged 65 and older who had knee or hip replacements. The goal was to unde…

This study looked at 674 patients who had a major heart attack (STEMI) to see if a simple blood test, called the TyG index, could predict how much damage their heart sustained. Researchers measured heart damage using detailed MRI scans about a week after the heart attack and trac…

This study followed over 4,400 older adults after surgery to understand how their physical frailty changed during recovery. Researchers tracked patients' frailty levels before surgery and at several points afterward to identify common recovery patterns. The main goal was to see i…

This study looked at whether a simple ratio from a routine blood test (lymphocyte-to-monocyte ratio) could help predict which older patients become confused after surgery. Researchers followed 6,475 patients aged 65 and older who had elective surgery. They specifically wanted to …