Chinese Pla General Hospital

This study tested a new way to monitor kidney oxygen levels during liver surgery to try to prevent acute kidney injury (AKI). 80 adults having liver surgery were randomly assigned to either standard care or extra monitoring that triggered a step-by-step treatment plan if oxygen l…

This phase 3 trial tested whether giving an individualized dose of antithymocyte globulin (ATG) based on a patient's own drug levels works better than a standard fixed dose. The goal was to reduce graft-versus-host disease (a serious immune reaction) and virus reactivation after …

This study tested a combination of six drugs (venetoclax plus CACAG regimen) against the standard '3+7' chemotherapy in 200 adults newly diagnosed with acute myeloid leukemia. The goal was to see if the new combo leads to more complete remissions after one treatment course. The t…

This study looked at whether a drug called trimetazidine can reduce scarring in the heart muscle after a heart attack. 194 people who had a specific type of heart attack took the drug for six months. Researchers used MRI scans to measure the amount of scarring.

This study looked at whether giving a steroid called methylprednisolone during anesthesia can prevent postoperative delirium (sudden confusion) in elderly patients having abdominal surgery. Researchers analyzed records from 25,800 patients aged 65 and older. The goal was to see i…

This completed study looked at medical records from over 10,000 men with enlarged prostate (BPH) in the UK and China. Researchers wanted to see if men taking 5-alpha reductase inhibitors (drugs like finasteride) had fewer heart problems like heart attacks and strokes. The study c…

This completed study looked at whether certain proteins in the blood (called biomarkers) can help predict acute graft-versus-host disease (aGVHD) in 500 patients who had a stem cell transplant for blood cancers. Researchers measured levels of REG3, ST2, IL-6, IL-8, and TNF R ever…

This study tested a 3D imaging navigation system to help guide HoLEP surgery for benign prostate enlargement. 150 men were split into two groups: one with the navigation system and one without. The goal was to see if the system reduces complications like urine leakage and urethra…

This study tested whether a single low dose of esketamine, given during anesthesia, could reduce anxiety and depression in 142 adults undergoing heart valve surgery. Participants were randomly assigned to receive either esketamine or a placebo (saline). The researchers measured m…

This study looked at whether giving a medicine called dexmedetomidine during major abdominal surgery can lower the chance of confusion (delirium) in patients aged 65 and older. About 268 elderly patients took part, and researchers checked for confusion twice a day while they were…

This study looks at whether certain antibiotics given before surgery are linked to postoperative delirium in adults over 65 having elective non-cardiac surgery. Researchers will track antibiotic use and check for delirium twice daily. The goal is to provide safety evidence to gui…

This study looked at nearly 30,000 older adults (65+) having non-cardiac surgery to see if levels of homocysteine, a natural amino acid, could predict serious complications like kidney injury or death. Researchers measured homocysteine before and after surgery. The goal was to se…

This completed study followed over 7,500 Chinese patients aged 65 and older who had non-cardiac surgery. Researchers measured how many developed anxiety or depression symptoms afterward using standard questionnaires. The goal was to find out how common these symptoms are and what…

This study looked at whether older adults with long-term pain before knee or hip replacement are more likely to feel depressed after surgery. Researchers analyzed data from 575 patients aged 65 and older. They found that chronic pain before surgery may predict depressive symptoms…

This completed study looked at whether a simple blood test measuring the ratio of two types of white blood cells (lymphocytes to monocytes) could help predict postoperative delirium—a state of confusion after surgery—in older adults. Researchers studied over 6,400 surgical patien…

This study followed over 4,400 older surgical patients to see how their frailty levels changed after surgery and whether those changes were linked to dying within one year. Researchers measured frailty before and after surgery and tracked deaths through phone calls. The goal was …

This study looked at older adults (65+) having surgery to see if delirium (sudden confusion after surgery) makes frailty worse and how that affects their risk of dying within a year. Researchers followed over 6,000 patients, checking frailty before and one month after surgery, an…

This study looked at 8,751 patients aged 65 and older who had elective non-cardiac, non-brain surgery. Researchers examined how patients' health and daily function before surgery related to serious heart and brain complications within 30 days after surgery. The goal was to compar…

This study looked at 674 people who had a severe type of heart attack (STEMI) and were treated with a procedure to open blocked arteries. Researchers checked if a simple blood test called the triglyceride glucose (TyG) index could predict how much heart muscle was damaged and the…

This completed study looked at how brain wave patterns change with age during desflurane anesthesia. Researchers recorded brain activity from 47 adults and elderly patients undergoing surgery. They analyzed different brain wave features to understand how aging affects the brain's…