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Microscope clue may spot hidden lung infection from stomach contents

NCT ID NCT07707206

Diagnosis Sponsor: Chinese PLA General Hospital Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jul 16, 2026 · Last updated Jul 17, 2026 · Updated 1 time

Summary

This study investigates whether 'showering cells' — a specific type of cell seen under a microscope in fluid from the lungs — can help diagnose aspiration pneumonia, a lung infection caused by inhaling food or stomach contents. Researchers will compare cell samples from 430 hospitalized adults with and without aspiration pneumonia to see if these cells are a reliable marker. If confirmed, this simple test could speed up diagnosis and treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could provide a faster, more accurate way to diagnose aspiration pneumonia using a simple microscope test.
What could go wrong
This is a retrospective study, so it can show associations but not prove cause. The findings need validation in larger, prospective trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

430 people

The number who actually took part.

Started

Jan 2018

Finished

Mar 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Inpatients with confirmed lung infection admitted to Chinese PLA General Hospital.

Ages

18 to 100 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age 18-100 years; 2. Clinically confirmed pulmonary infection; 3. Completion of bedside BAL; 4. Qualified BALF specimens submitted for M-ROSE examination; 5. Complete clinical and radiological data. Exclusion Criteria: 1. Age \<18 years or \>100 years; 2. Diagnosis of noninfectious pulmonary diseases; 3. No bronchoscopy or BAL examination; 4. BALF samples not assessed by M-ROSE, acquired images were of poor quality, or samples were unqualified; 5. Missing key clinical data precluded group assignment.

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Conditions

The condition(s) this trial relates to.

aspiration pneumonia

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Pneumonia, aspiration

Contacts and locations

Locations

  • Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100000, China

More trials for these conditions

Other studies related to the condition(s) this trial covers.