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Classical music vs. anxiety: a simple test in the eye clinic

NCT ID NCT05904392

Symptom relief Sponsor: Althaia Xarxa Assistencial Universitària de Manresa Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 15, 2026 · Last updated Sep 16, 2026 · Updated 1 time

Summary

Intravitreal injections deliver medicine directly into the eye and are usually quick, but many patients feel anxious before and during the procedure. Researchers are testing whether playing classical music during the injection lowers anxiety and pain compared with no music. The trial enrolls 50 adults who have had at least one prior eye injection and randomly assigns them to hear music or not. Participants fill out anxiety questionnaires and rate their pain before and after the procedure.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
classical music played during the procedure
What this could lead to
If music helps, eye clinics could add a free, low-risk step to make injections less stressful for patients who return for repeated treatment.
What could go wrong
The trial is small and single-center, so any calming effect may be modest or may not hold for patients with diagnosed anxiety disorders, who are excluded.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

50 people

The number who actually took part.

Started

Feb 2023

Finished

Apr 2023

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients must be at least 18 years old. * Patients must have been prescribed an intravitreal injections of an anti-VEGF drug. * Subjects must have undergone at least one previous intravitreal injection. * Patients must fully understand the procedure and the project they will be participating in and agree on signing the informed consent. Exclusion Criteria: * Patients with a psychiatric diagnosis with the need to take anxiety medication. * Patients that before the intervention took medication to relax, such as benzodiazepines or anxiolytics. * Subjects with hearing difficulty.

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Conditions

The condition(s) this trial relates to.

anxiety disorder Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety and fear

Contacts and locations

Locations

  • Eduard Pedemonte Sarrias

    Manresa, Barcelona, 08243, Spain

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