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Mind over microbes? new study probes Brain-Immune link in 700 slovaks

NCT ID NCT07070180

Knowledge-focused Sponsor: Comenius University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study in Slovakia examined how psychological factors like resilience, stress, and positive thinking relate to the body's immune system. Researchers measured immune markers in blood and compared them to mental health questionnaires in 700 adults, including people in treatment for alcohol addiction. The goal was to better understand the mind-body connection, not to test a new treatment.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this could help explain how mental states like resilience and stress affect physical immunity, pointing toward new ways to support overall health.
What could go wrong
This is an observational study, not a treatment trial. It cannot prove cause and effect, and results may not apply to other populations.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

700 people

The number who actually took part.

Started

Jan 2024

Finished

Dec 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

'General Slovak Population Sample' will be selected from adult population aged 18-50 years living in Bratislava, Banská Bystrica and Košice regions. Participants were recruited through media promotion of the research. The study group was selected from the registered volunteers based on stratification by age and sex, with equal representation across the age groups 18-30, 31-40, and 41-50 years. The sample 'Individuals receiving inpatient treatment for alcohol addiction at the treatment facility' was selected from patients admitted at addiction treatment facility within 48 hours of their admission. The study sample included 100 volunteers aged 18-50 years.

Ages

18 to 50 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria for 'General Slovak Population Sample': * Age between 18 - 50 years * Residency in the respective region for at least five years * Consent to participate in the study Exclusion Criteria for 'General Slovak Population Sample': * Individuals younger than 18 or older than 50 years * Ongoing acute infectious disease on the day of testing * Eligible individuals who do not provide informed consent Inclusion Criteria for the sample 'Individuals receiving inpatient treatment for alcohol addiction at the treatment facility': * Age between 18 - 50 years * Admission to treatment for alcohol addiction * Consent to participate in the study, Treatment completion Exclusion Criteria for the sample 'Individuals receiving inpatient treatment for alcohol addiction at the treatment facility': * Individuals younger than 18 or older than 50 years * Eligible individuals who do not provide informed consent * Drop-out from alcohol addiction treatment

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Conditions

The condition(s) this trial relates to.

alcohol abuse anxiety disorder Depression Fractures, Stress Self-Control

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Adverse childhood experience Anxiety symptoms Cytokine levels Depression symptoms Immunity Mindfulness Positive thinking Problem solving Psychological adaptation Psychological distress Resilience Self-control Sense of coherence Sense of control Socio-economic status Stress Stress response

Contacts and locations

Locations

  • Comenius University Bratislava, Faculty of Arts

    Bratislava, 81102, Slovakia

  • Comenius University, Faculty of Medicine in Bratislava

    Bratislava, 81108, Slovakia

  • Slovak Academy of Sciences, Institute of Neuroimmunology

    Bratislava, 84510, Slovakia

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