Soothing sounds may shield seniors from ICU brain fog

NCT ID NCT04182334

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study tested whether listening to slow-tempo music through noise-cancelling headphones twice a day could help older adults in the ICU avoid delirium—a state of confusion linked to longer hospital stays and lasting cognitive problems. Researchers enrolled 160 critically ill patients aged 50 and older who were on breathing machines. For up to seven days, one group listened to slow music while a control group wore the same headphones without music. The goal was to see if music increased days free of delirium and coma.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

slow-tempo music listening sessions

What this could lead to

If it works, this could offer a simple, drug-free way to reduce delirium and improve recovery for older ICU patients.

What could go wrong

This is a small, completed study without a phase designation, so results may not be definitive or widely applicable. The benefit may be modest or not reproducible in larger, more diverse groups.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder delirium Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Eskenazi Hospital

    Indianapolis, Indiana, 46202, United States

  • IU Health University Hospital

    Indianapolis, Indiana, 46202, United States

  • IU Health West Hospital

    Avon, Indiana, 46123, United States

  • Mayo Clinic Rochester

    Rochester, Minnesota, 55905, United States

  • Methodist Hospital

    Indianapolis, Indiana, 46202, United States