Can antidepressants and exercise ease chronic back pain?
NCT ID NCT04747314
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at whether an antidepressant, physical therapy, or a combination of both can help people with chronic low back pain who also struggle with negative feelings. About 308 adults aged 18-75 with pain lasting over 6 months took part. The goal was to see if these treatments improve pain, daily function, and mood.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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BWH Pain Management Center
Chestnut Hill, Massachusetts, 02467, United States
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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UPMC Pain Medicine At Centre Commons
Pittsburgh, Pennsylvania, 15206, United States
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