New combo therapy targets pain and depression in back pain sufferers

NCT ID NCT04747314

First seen Jan 12, 2026 · Last updated May 13, 2026 · Updated 18 times

Summary

This study tested whether antidepressants, physical therapy, or a combination of both can help people with chronic low back pain who also struggle with negative emotions. Researchers measured improvements in pain, daily function, and depression. The goal was to find better ways to treat both the physical and emotional aspects of chronic pain.

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Contacts and locations

Locations

  • BWH Pain Management Center

    Chestnut Hill, Massachusetts, 02467, United States

  • Mayo Clinic

    Rochester, Minnesota, 55905, United States

  • UPMC Pain Medicine At Centre Commons

    Pittsburgh, Pennsylvania, 15206, United States

Conditions

Explore the condition pages connected to this study.