Which therapy eases back pain disability best? a Head-to-Head trial

NCT ID NCT05294081

First seen Aug 12, 2026 · Last updated Aug 13, 2026 · Updated 1 time

Summary

This trial compares two psychological approaches for chronic low back pain: exposure therapy and cognitive behavioral therapy (CBT). The goal is to see which method better reduces pain-related disability and to identify which patients benefit most from each. Adults with chronic back pain and significant disability will receive 10 sessions of one therapy and be followed for up to two years.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Exposure therapy and cognitive behavioral therapy
What this could lead to
If successful, this could help tailor psychological treatments for chronic back pain, improving disability outcomes for specific patient groups.
What could go wrong
The trial is early and results may not apply to all patients. Psychological therapies require active participation and may not work for everyone.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Essener Rückenschmerzzentrum, Universitätsklinikum Essen

    Essen, 45147, Germany

  • Phillips-Universität Marburg

    Marburg, 35037, Germany

  • Poliklinische Institutsambulanz für Psychotherapie

    Mainz, 55122, Germany

  • RPTU Kaiserslautern- Landau

    Landau, RLP, 76829, Germany

  • Schmerzzentrum, Ruprechts - Karls Universität Heidelberg

    Heidelberg, 69120, Germany

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