Resilience training shows promise for teens facing advanced cancer
NCT ID NCT03668223
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a program called PRISM that teaches stress management, goal-setting, and coping skills to adolescents and young adults (ages 12-24) with advanced cancer. Researchers wanted to see if it could improve quality of life and reduce anxiety and depression. The program involves several one-on-one coaching sessions and was compared to usual care in a randomized trial across multiple hospitals.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Promoting Resilience in Stress Management (PRISM) behavioral intervention
- What this could lead to
- If it works, this program could help teens and young adults with advanced cancer feel better emotionally and cope more effectively with their illness.
- What could go wrong
- This is a completed trial with 195 participants, but the intervention is behavioral—it may not work for everyone, and benefits might be modest or not last long-term.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Hospital Los Angeles
Los Angeles, California, 900278, United States
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Dana Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Seattle Children's Hospital
Seattle, Washington, 98145, United States
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Texas Children's Hospital
Houston, Texas, 77030, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15213, United States
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