Scientists probe the chemistry of tooth pain and stress
NCT ID NCT07330024
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at 72 adults to see how certain chemicals (Substance P and CGRP) in saliva and tooth pulp relate to dental pain, inflammation, and stress. Participants provided saliva samples and had pulp tissue collected during routine root canal treatment. The goal was to better understand the link between psychological factors and dental pain.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- What this could lead to
- If successful, this could help dentists better understand and manage dental pain by considering both biological and psychological factors.
- What could go wrong
- This is a small, observational study that only measures associations, not causes. Results may not apply to everyone or lead to direct treatments.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Kahramanmaraş Sutcu İmam University, Faculty of Dentistry
Kahramanmaraş, onikişubat, 46010, Turkey (Türkiye)
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