Can a common anxiety drug alter heart rhythm? a trial investigates
NCT ID NCT06065735
First seen Aug 19, 2026 · Last updated Aug 19, 2026
Summary
This trial investigates whether paroxetine, a drug used for anxiety, affects the heart's electrical activity (QT interval) in healthy adults. Participants will take increasing doses of paroxetine, and their heart rhythm will be monitored via ECG. The study aims to see if any dose-related changes in heart rhythm occur and to assess safety.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- paroxetine
- What this could lead to
- If successful, it could confirm that paroxetine is safe for the heart, supporting its use in treating anxiety disorders.
- What could go wrong
- This is an early-phase study in healthy volunteers, so results may not reflect real-world patients. Paroxetine may still cause heart rhythm changes or other side effects.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
GSK Investigational Site
London, HA1 3UJ, United Kingdom
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