Stroke disorder

This phase 3 trial tests whether adding a clot-busting drug (alteplase) directly into the brain artery during mechanical clot removal improves recovery for people with severe stroke. About 440 participants with large vessel blockages will be randomly assigned to receive the drug …

This study compares video-based nurse consultations to standard in-person visits for people who recently had a stroke. About 196 participants will be randomly assigned to either telecare or face-to-face follow-up. The goal is to see if remote care can maintain or improve disabili…

This study tests whether drinking a protein beverage after leg-strengthening exercises helps stroke survivors rebuild muscle better than exercise alone. About 93 people who had a stroke more than 3 months ago will take part. Researchers will measure changes in thigh muscle size, …

This study tested whether giving the cholesterol-lowering drug evolocumab within 24 hours after clot-busting treatment (thrombolysis) can prevent early neurological decline in people with acute ischemic stroke. 132 participants were randomly assigned to receive evolocumab plus st…

This trial tests whether a home-based virtual reality rehabilitation program called Muvity can improve arm function, balance, and quality of life in people who had a stroke more than six months ago. Participants will be split into two groups: one doing the Muvity program at home …

This trial tests a virtual reality system called RGS that guides stroke survivors through reaching, grasping, and placing virtual objects to aid motor and cognitive recovery. The study enrolls adults who have had a first stroke with mild to moderate arm weakness. Participants use…

This study tested a set of simple, affordable robots called Rehab CARES to help older adults who had a stroke improve arm and hand function. Twenty-seven participants used the robots for one-hour sessions, three times a week for four weeks, while also receiving standard therapy. …

This trial compares two types of technology-assisted balance training for people who had a stroke at least six months ago. One group trains balance using ankle movements, the other uses hip movements, and both also receive a standard rehabilitation program. The goal is to see whi…

This trial tests whether delivering electrical stimulation underwater can help people recovering from a stroke regain hand grip strength and arm movement. Participants who had a stroke within the past six months will receive either real underwater faradic stimulation or a sham ve…

This trial asks whether adding motor imagery—mentally rehearsing hand movements without physically moving—to robot-assisted hand rehabilitation can improve daily living skills in people recovering from stroke. Forty participants will be randomly assigned to receive either robot-a…

This trial tests whether pairing vagus nerve stimulation (VNS) with rehabilitation can improve arm function in people who have had an ischemic stroke. Participants receive an implanted VNS device and undergo weeks of therapy, with some receiving active stimulation and others a sh…

This study tests whether the blood thinner edoxaban can prevent strokes in people with atrial fibrillation (an irregular heartbeat) who have already survived a brain bleed. About 948 participants will receive either edoxaban or non-anticoagulant therapy (like aspirin or no blood …

This trial tests whether a rehabilitation technique called error-augmented walking can improve gait and brain activity in people who have had a stroke. Participants walk on a split-belt treadmill, which makes the two belts move at different speeds to create a deliberate mismatch,…

This phase 2 trial tests whether levosimendan, a heart medication that widens blood vessels, can reduce dangerous artery spasms and delayed brain injury after a type of bleeding stroke called aneurysmal subarachnoid hemorrhage. Thirty adults in intensive care will receive either …

This phase 3 trial tests whether a monthly injection of pelacarsen can reduce major heart problems like heart attacks and strokes in people with high levels of Lp(a), a genetic risk factor. Over 8,000 participants with existing heart disease are being followed for several years. …

This trial tests whether adding respiratory muscle training to a standard post-stroke wellness program improves breathing strength, physical activity, and quality of life more than the wellness program alone. Stroke survivors who are at least six months post-stroke will participa…

This trial tests a new rehabilitation approach for people who have had a stroke and have lasting hand impairment. Participants wear a soft robotic glove that senses and assists finger movements, combined with targeted electrical stimulation of nerves, while practicing finger move…

This trial explores whether combining hyperbaric oxygen therapy with moderate-intensity aerobic exercise can improve working memory in older adults who have mild cognitive impairment after a stroke. Participants, aged 65-85, will be randomly assigned to receive either this combin…

This observational study is evaluating the safety and effectiveness of apixaban, a blood thinner, in frail Korean patients with atrial fibrillation (an irregular heartbeat) who are at high risk for stroke and bleeding. The study will follow about 2,000 patients who are older, hav…

This study tests whether adding an anti-gravity treadmill and high-intensity electromagnetic stimulation to standard physical therapy helps people recover walking and balance after a recent stroke. Participants are adults aged 18 to 74 who had a stroke and need help moving. They …

This trial tests whether a device that gently stimulates the tongue, called PoNS, can improve balance and walking in people who had a stroke at least six months ago. Participants receive either real stimulation or a sham (inactive) device, along with balance training, over severa…

This study compares two treatments for a severe type of stroke caused by a blockage in a major artery at the base of the brain. Some patients will get a clot-busting drug through a vein followed by a procedure to remove the clot, while others will have the clot removal procedure …

This study tests whether using a brain-computer interface (BCI) to control a walking robot can improve gait recovery after a stroke. People who had a stroke within the past year will be randomly assigned to either standard exoskeleton training or BCI-controlled exoskeleton traini…

This study tests whether a program called iHeLP is practical and acceptable for stroke survivors. The program includes a one-on-one interview to set personal goals, followed by six weekly group sessions focused on healthy lifestyle changes. Researchers will measure how many peopl…

This pilot study tested whether community pharmacists can manage blood thinner therapy for older adults (60+) with atrial fibrillation who are at high risk for stroke but not on optimal treatment. Fourteen participants received pharmacist-led care for 3 months, then were followed…

This trial tests whether giving stroke or TIA survivors free smoking-cessation medications (like nicotine patches, bupropion, or varenicline) for 12 weeks helps them quit smoking more effectively than just giving a prescription. The study will compare quit rates and cost-effectiv…

This trial compares two medications, ephedrine and phenylephrine, used to treat sudden low blood pressure during carotid surgery. The main question is whether one drug better preserves oxygen levels in the brain during the procedure. The study involves adults undergoing planned c…

This trial tests whether low-intensity focused ultrasound (LIFU) can safely stimulate the brain to help people recover arm and hand function after a stroke. Researchers will try different intensities and frequencies of ultrasound in stroke survivors to find the best settings that…

This trial tests whether giving a clot-busting drug called tenecteplase directly into the brain artery, right after a standard procedure to remove a clot, can help people who have had a severe ischemic stroke. The study includes adults aged 18-85 with a blocked artery in the fron…

This trial tests whether stroke patients with bulbar palsy—a condition that makes swallowing difficult—are less likely to develop pneumonia if they receive nutrition through a nasogastric tube or through an IV (total parenteral nutrition). The study will compare the incidence of …

This trial compares two techniques for guiding botulinum toxin injections to treat leg spasticity after a stroke: ultrasound and electrostimulation. The goal is to see which method improves ankle flexibility and reduces pain during the procedure. Adults with stroke-related spasti…

This study tested whether a physical activity program delivered by mail and website could improve the health of nearly 50,000 older women already in the Women's Health Initiative. The program included aerobic, balance, strength, and flexibility exercises, and encouraged reducing …

This study tests whether an implanted device that stimulates the vagus nerve, combined with physical therapy, can improve arm movement in people who have had a stroke. The trial includes adults with chronic upper-limb weakness who have already received the implant and completed r…

This trial tests whether combining robotic gloves with task-oriented mirror therapy can improve hand motor function in people recovering from a stroke. Thirty sub-acute stroke patients will receive either the combined therapy or mirror therapy alone, alongside standard rehabilita…

This study tested whether a specially designed stroke unit at the University Teaching Hospital in Lusaka, Zambia, improves care and survival for adults with stroke. The unit uses local protocols and trained staff to standardize treatment. Researchers compared outcomes for 300 pat…

This trial compares two low-cost exercise programs—Cawthorne-Cooksey exercises and Frenkel exercises—to see which better improves balance and coordination in people who had a stroke 3 to 6 months ago. Participants, aged 40 to 75 with moderate balance problems, will be assigned to…

This study tests a drug called Ir-CPI in 23 people who have had a bleeding stroke (intracerebral hemorrhage). The drug is given once through a vein over 48 hours, alongside standard care. The goal is to see if it is safe and can reduce swelling and further brain damage around the…

This study investigates whether a noninvasive brain stimulation technique called transcranial direct current stimulation (tDCS) can enhance recovery from spatial neglect — a condition where stroke survivors ignore one side of their world. Participants who had a stroke 3 to 12 mon…

This study tests whether combining two types of electrical stimulation can improve hand and arm movement in people who recently had a stroke. One stimulation is applied to the brain (tDCS) and the other to a nerve in the wrist. Participants receive five daily sessions, and their …

This study compares two types of walking exercise for people who have had a stroke at least six months ago: walking in virtual reality (wearing VR glasses showing a nature walk) and walking on a treadmill. Both groups also receive standard physical therapy. The goal is to see whi…

This study tests whether a six-week program that combines stepping to a metronome (rhythmic auditory stimulation) with walking while carrying objects (motor dual-task training) can improve mobility, balance, and quality of life in people who had a stroke at least six months ago. …

After a stroke, patients are at high risk of having another one, especially in the first 21 days. This study tests whether adding clopidogrel to the standard aspirin treatment is safe and feasible for preventing a second stroke. About 200 patients who had a mild to moderate strok…

This study tests whether a robotic hand device can improve grip strength and fine motor skills in people who had a stroke at least six months ago. Participants use the HWARD exoskeleton, which assists hand opening and closing, during 45-minute sessions three times a week for 12 w…

This study tested whether giving a powerful cholesterol-lowering drug (evolocumab) within 6 hours after a stroke procedure (thrombectomy) could prevent early neurological worsening. 60 adults with large-vessel stroke were randomly assigned to receive either the drug plus standard…

This trial investigates whether a structured exercise program can improve fitness and lower risk factors for heart disease, stroke, and type 2 diabetes in Latina women who have had breast cancer. Participants are randomly assigned to either an 8-month progressive exercise program…

This study tests whether adding mixed reality games to standard physical therapy helps people who have had a stroke regain arm movement and trunk stability. Participants will either receive traditional therapy alone or traditional therapy plus sessions using a mixed reality heads…

This study tests two strategies in low-income seniors with chronic conditions like heart disease, diabetes, or kidney disease. One group gets free preventive medications (no copayment), and another receives personalized education on medication use and lifestyle. The goal is to se…

This clinical trial tests whether adding the drug glenzocimab to standard endovascular therapy (a procedure to remove blood clots) improves recovery in people with acute ischemic stroke. The study includes adults aged 18 and older who are eligible for clot removal within 24 hours…

This study tests whether a robotic hand device can help people recovering from a stroke improve hand strength and dexterity better than standard physical therapy. Thirty adults with sub-acute stroke (2 weeks to 6 months post-stroke) will be randomly assigned to receive either rob…

This study tests whether playing motion-controlled video games—like boxing, bowling, and table tennis—using a Kinect sensor can improve trunk control, balance, and arm function in people recovering from a stroke. Forty participants aged 40 and older, at least three months post-st…

This study tests whether a structured nursing program, based on the Plan-Do-Check-Act quality improvement cycle, can reduce lung infections in stroke patients who have a tracheostomy (a breathing tube in the neck). The program includes careful airway care, suctioning, and early r…

This study compares three rehabilitation techniques—mirror therapy, proprioceptive neuromuscular facilitation (PNF), and constraint-induced movement therapy (CIMT)—for helping stroke survivors regain arm and hand function. Ninety adults with arm weakness after stroke receive one …

This study compares a virtual reality (VR) rehabilitation program that combines movement and cognitive training in realistic everyday environments with conventional occupational therapy for people who have had a stroke. The goal is to see if the VR program leads to greater improv…

This pilot study tests a new non-invasive brain stimulation device called kTMP (kilohertz transcranial magnetic perturbation) to see if it can improve arm and hand movement in people who had a stroke more than six months ago. The study enrolls 7 adults aged 18-80 with stable uppe…

This phase 2 trial tested a new gel called OTR4132 in 60 people who had a stroke and received a clot-removal procedure. The gel is designed to help repair damaged brain tissue. Researchers measured neurological function at 24 hours and disability at 3 months to see if the gel imp…

This trial investigates whether adding strength training for the tibialis anterior muscle (which lifts the foot) to proprioceptive (balance) exercises improves recovery in people who had a stroke at least six months ago. Participants will be assigned to six weeks of either balanc…

This study compares two different doses of Wii Fit-based virtual reality balance training added to standard physical therapy for people who had a stroke at least six months ago. Participants are randomly assigned to receive either conventional rehab alone, or conventional rehab p…

This study tested whether a special balloon procedure, called direct ischemic post-conditioning, can reduce brain injury in people who just had a stroke from a large blocked artery. Sixty patients were randomly assigned to get either standard clot removal alone or clot removal pl…

This study tested a soft robotic sock called VACOM in 19 stroke patients who had trouble moving their ankle. The sock gently moves the ankle to prevent stiffness and improve blood flow, aiming to reduce the risk of blood clots and contractures. The trial is complete, but results …

This study looked at whether a therapeutic education program, added to standard medical care, helps people who have had a heart attack or stroke better control their risk factors over one year. About 202 adults aged 18-75 took part. The goal was to see if the program improves phy…

This pilot study tested whether adding cognitive rehabilitation to a standard occupational therapy telerehabilitation program helps stroke survivors improve thinking, arm function, and mood. Twenty adults who had a stroke at least 30 days prior participated in an 8-week home-base…

This study tested a new intensive therapy called I-ACQUIRE for infants aged 8 to 36 months who had a stroke around birth and have weakness on one side. The therapy involves guided play and movement exercises for either 3 or 6 hours a day, 5 days a week for 4 weeks. Researchers co…

This pilot study tested a device called Fesia Grasp that uses electrical stimulation to help people recovering from a stroke regain hand function. Sixteen participants with arm weakness after a subacute stroke received either Fesia Grasp therapy or standard physical therapy. The …

This study tested whether the drug rivaroxaban works as well as warfarin to prevent further brain damage in people who have had a stroke due to antiphospholipid syndrome (APS), a condition that causes abnormal blood clotting. About 40 participants took either rivaroxaban or warfa…

This completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often …

This study tested whether a newer blood thinner, rivaroxaban (Xarelto), is as safe and effective as the older drug warfarin for preventing strokes in people who develop atrial fibrillation after heart surgery. About 100 adults who had open-heart surgery and then experienced a new…

This study tested a new way of caring for stroke patients that brings together doctors, nurses, and family members using technology and teamwork. About 1,200 adults who had a stroke took part. The goal was to see if this coordinated care helps people recover better and have a hig…

This study tested whether using social networks (like family and friends) can help people at high risk for stroke stick to their medications and control risk factors after leaving the hospital. Researchers enrolled 720 patients and compared standard care with a social network-bas…

This study looked at whether a procedure to remove a blood clot from the brain (endovascular therapy) works better than medication alone for people with mild stroke symptoms and a visible clot. About 4,800 adults with mild stroke were included. The goal was to see which approach …

This study tested a 6-month program called TEAM designed to help African-American men who have had a stroke or mini-stroke manage their health better. The program included group sessions with a nurse and peer educators, focusing on lifestyle changes to lower blood pressure and ch…

This completed trial tested whether combining a gentle brain stimulation technique called tDCS with intensive rehabilitation can improve hand function in children with hemiplegic cerebral palsy caused by perinatal stroke. 89 children participated, and the study measured changes i…

This study tested a rehabilitation technique called blood flow restriction training (BFRT) in 70 stroke survivors with arm weakness on one side. Participants did low-intensity exercises while wearing a cuff that partially restricted blood flow to the affected arm. The goal was to…

This completed study tested a device called MR-001 that uses rhythmic auditory stimulation (like music or beats) to help people who have had a stroke walk better. 234 chronic stroke patients with walking problems used the device at home for 12 weeks. The goal was to see if it imp…

This study tested whether a 40-hour, 8-week cognitive telerehabilitation program could reduce the risk of memory and thinking problems after a stroke. 86 adults who recently had a stroke were randomly assigned to either the home-based brain training or standard care. The program …

This study tested whether a powerful blood thinner called tirofiban can improve recovery in people with a specific type of stroke called branch atheromatous disease (BAD). BAD strokes often get worse quickly and have few good treatments. The trial enrolled 516 adults within 48 ho…

This pilot study tested whether low-frequency magnetic stimulation (rTMS) applied to the brain within 48 hours of an acute ischemic stroke could reduce the growth of damaged tissue and lower disability. Sixty adults aged 18–80 with moderate to severe strokes were enrolled. The tr…

This study tested two blood thinners—tirofiban and aspirin—in 240 stroke patients who also had a severe blockage in the neck artery. The goal was to see which drug better prevents the artery from reclosing after emergency surgery, while also checking for bleeding risks. Results w…

This completed study tested a health system intervention called ENHANCE in 1,837 adults aged 40+ with at least two chronic conditions (HIV, high blood pressure, diabetes, asthma, or depression). The intervention included a clinical decision support tool for clinicians, health edu…

This study tested an experimental drug called SCP776 in 120 adults having emergency surgery to remove a blood clot after a severe stroke. The goal was to see if the drug is safe and helps protect the brain from further damage. Participants received either the drug or a placebo, a…

This study tested whether special pelvic floor exercises can help stroke survivors who have weak pelvic muscles and sexual problems. 140 people who had a stroke at least a year ago took part. The goal was to see if these exercises improve muscle strength and sexual function over …

This study tested a program to help people with heart disease, stroke, or heart failure in India. The program used non-physician health workers, text messages about healthy living, and a computer tool to help doctors make decisions. 410 adults took part to see if the program impr…

This study compares two ways to remove large blood clots from the brain during a stroke: direct aspiration (ADAPT) and using a stent retriever. About 381 adults with stroke caused by a blocked artery in the front part of the brain took part. The goal is to see which method clears…

This study tested whether intensive, coordinated follow-up by nurses, doctors, and pharmacists over two years helps people recover better after a stroke or heart attack compared to standard care. Researchers enrolled 859 participants and measured quality of life and healthcare co…

This study tested whether adding Mexidol to standard stroke care helps people recover better after a first ischemic stroke. 304 adults who had a stroke within 48 hours were given either Mexidol or a placebo for about 10 weeks. Researchers measured disability, neurological symptom…

This study tested whether stroke patients over 60 with high blood pressure benefit from extra nurse-led education and follow-up, compared to standard care. About 290 patients took part, each bringing a family member or friend to help. The main goal was to see if this approach low…

This study looked at whether getting vitamin D levels above 40 ng/mL after a heart attack could reduce the chance of death, another heart attack, stroke, or heart failure hospitalization. About 634 heart attack patients were split into two groups: one got standard care, and the o…

This study tested a procedure to close a small pouch in the heart (left atrial appendage) in people with atrial fibrillation who are at high risk for both stroke and bleeding. The goal was to see if this procedure works better than standard blood-thinning medications at preventin…

This study tested a new medicine called MLC1501 to help people recover after a stroke. 303 adults who had a stroke within the past 2 to 10 days took either a high dose, low dose, or a placebo pill twice a day for 24 weeks. The main goal was to see if MLC1501 improves motor functi…

This large study looked at whether taking daily vitamin D or fish oil supplements could lower the risk of developing autoimmune diseases (like rheumatoid arthritis), reduce signs of inflammation in the blood, and ease chronic knee pain. Over 25,000 adults without prior cancer or …

This study looked at whether raising the head after a stroke procedure helps patients recover better. Over 1,300 adults with severe strokes were followed for 90 days to see if head elevation improved their ability to function. The goal was to find a simple, low-cost way to boost …

This study looked at 260 people having emergency stroke treatment to remove a clot. Some were given sedation (awake but relaxed) and others were put under general anesthesia (completely asleep). The goal was to see which approach leads to better recovery and fewer complications a…

This study tested whether rosuvastatin, a common cholesterol-lowering drug, could reduce early signs of artery hardening in 121 people with ANCA-associated vasculitis. Participants were in remission and received either rosuvastatin or a placebo for up to 2 years. The goal was to …

This pilot study tested a procedure to close the left atrial appendage—a small pouch in the heart where clots often form—in 58 patients with atrial fibrillation who had a prior brain bleed and cannot take standard blood thinners. The goal was to see if this approach could reduce …

This early-stage study tested a drug called PP-007 in 24 people having an acute ischemic stroke. The drug is designed to carry oxygen to the brain. Researchers checked if adding it to standard treatments like clot-busting drugs or clot removal was safe. The goal was to see how th…

This study tracked 949 patients with non-valvular atrial fibrillation who received the WATCHMAN FLX Pro device, a small implant that closes off a part of the heart to reduce stroke risk. The goal was to see how well the device works in everyday medical practice, focusing on safet…

This trial tested two blood thinners—rivaroxaban (Xarelto) and aspirin—in over 1,200 people with atrial fibrillation who had a successful ablation procedure. The goal was to see which one better prevents strokes and silent brain clots. Participants were followed for three years w…

This study tested whether the drug Mexidol (given first as injections, then as pills) can improve thinking and memory in people with chronic cerebral ischemia, a condition where the brain doesn't get enough blood flow. 318 adults aged 40-90 with mild to moderate cognitive impairm…

This completed trial enrolled 2,486 people with asymptomatic high-grade carotid stenosis (narrowing of the neck arteries) to see if adding surgery or stenting to intensive medical management reduces stroke risk more than medical management alone. Participants were randomly assign…

This study tested whether a personalized, 18-month follow-up program with a stroke coordinator could help prevent long-term functional decline in 301 stroke survivors. Participants received monthly meetings to address physical, cognitive, social, and lifestyle needs. The goal was…

This completed Phase 4 trial tested a herbal supplement called AntiCov-220 in 82 people with underlying health conditions, including HIV and cancer. The goal was to see if it could prevent and treat COVID-19 by boosting the immune system and fighting the virus. The study compared…

Researchers are testing whether a bedside ultrasound of the eye can help emergency doctors tell ischemic stroke (caused by a clot) from hemorrhagic stroke (caused by bleeding). The team measures the optic nerve sheath diameter, a marker linked to pressure inside the skull, in adu…

Researchers are studying whether ultrasound images of carotid artery plaques can reveal which plaques are unstable and more likely to cause a stroke. They compare scan features with the actual tissue composition of plaques removed during surgery, and they track plaque growth, str…

This study tests whether smartwatches can detect atrial fibrillation (AF) in people who recently had a stroke. Participants already have an implanted heart monitor (the gold standard) and will also wear a smartwatch for 12 weeks. The goal is to see how well the smartwatch catches…

This trial tests whether a wearable device called MobiCARE, worn for 7 days, can spot undiagnosed atrial fibrillation—an irregular heartbeat that raises stroke risk—in people who have had a routine health check-up. The study enrolls adults with stroke risk factors, such as high b…

This study tests whether a tablet version of the Oxford Cognitive Screen (OCS) can accurately identify cognitive issues like spatial neglect and attention problems in people who have had a stroke. Researchers will compare results from the tablet test with the traditional paper ve…

This trial evaluates the safety and feasibility of a portable, low-field MRI device called Axana for imaging the brain in people with suspected stroke. Researchers will compare scans from the Axana device with standard hospital MRI scans in 60 adults, including healthy volunteers…

This trial tests whether a new device, placed gently in the ear canal, can accurately measure pressure inside the skull without surgery. The device works by detecting tiny changes in inner-ear activity that reflect pressure shifts in the brain. It will be compared to the standard…

This study tested a new imaging method to detect inflammation in fatty plaques that cause strokes. It involved 3 men who had a recent stroke and were scheduled for surgery to remove a plaque in their neck artery. The goal was to see if a special PET scan tracer could highlight in…

This study tested a new tool called BESTA, designed to quickly diagnose aphasia (language problems) in people who just had a stroke. Researchers compared BESTA to an existing test in 395 participants, including stroke patients and healthy volunteers. The goal was to see if BESTA …

This study looked at whether measuring two proteins in the blood (GST-π and PRDX1) can accurately determine if a stroke occurred within the last 4.5 hours. That time window is critical because it determines if patients can receive clot-busting medication. Researchers enrolled 935…

This study tested whether a special CT scan done in the procedure room can accurately detect bleeding in the brain of stroke patients. The goal is to speed up diagnosis and treatment by avoiding extra trips to the regular CT scanner. 252 adults with stroke symptoms were enrolled …

This study tested a device called NIRSITX that uses light to measure oxygen levels in the brain. Researchers compared oxygen readings from the injured side of the brain to the healthy side in 35 adults who had a stroke within the past week. The goal was to see if the device could…

This study tested a new thinking test called CASP for stroke patients. The test is designed to work even for patients who have trouble speaking after a stroke. Researchers checked how well the test works by comparing it to other tests in 263 patients.

This study tested whether a special eye-tracking device (video-oculography) helps emergency room doctors more accurately diagnose the cause of vertigo or dizziness. About 130 adults with dizziness were randomly assigned to get either the eye-tracking test plus standard care, or s…

This study tested a special PET/MR scan using a radioactive tracer called 18F-sodium fluoride to see if it can better identify dangerous carotid artery plaques. The researchers compared 6 patients who recently had a stroke with 6 who had no symptoms, all with significant plaque b…

This study tested whether an ultrasound of the optic nerve sheath (the lining around the nerve connecting the eye to the brain) can accurately detect dangerously high pressure inside the skull in children. Researchers measured the nerve sheath diameter in 230 children with brain …

This study tests whether giving probiotics (LactoLevure) to ICU patients on ventilators can prevent ventilator-associated pneumonia. The trial will enroll 186 adults with head injury, stroke, or brain hemorrhage. Patients receive probiotic or placebo capsules twice daily for 30 d…

This trial tests a program called TEAM, designed to help people at high risk for stroke lower their risk factors. The program involves nurses and peer educator pairs working with patients and their care partners through one-on-one and group sessions. The goal is to see if this ap…

This study tested a new way to position the weak arm in stroke patients to prevent shoulder pain, a common problem that can slow recovery. 76 people who had a stroke within the last 48 hours took part. The program used special supports and slings, along with training for patients…

This completed clinical trial tested a procedure called ischemic postconditioning to prevent brain damage in 40 people undergoing carotid surgery for severe artery narrowing. The procedure involves briefly clamping and unclamping the carotid artery in cycles after surgery to prot…

This study looked at whether a simple oral hygiene routine could prevent a serious lung infection called aspiration pneumonia in people hospitalized after a stroke. Researchers compared 90 stroke patients who received structured mouth care from nurses to similar patients who got …

This large, completed phase 3 trial tested whether a single pill containing three low-dose blood pressure medicines (telmisartan, amlodipine, and indapamide) could prevent another stroke in 1,671 people who had previously had a bleeding stroke (intracerebral haemorrhage) and had …

This study tested a custom-made shoulder sling (EO31) in 25 adults who had a stroke within the last 6 months. The goal was to see if the sling could prevent shoulder pain and other complications. Researchers measured success using a goal-setting scale and pain scores. This is a s…

Researchers are testing whether stroke patients can safely use a hand rehabilitation robot called ReHandyBot on their own, first in a clinic and then at home. The study enrolls 15 adults who recently had a stroke and have hand weakness. Participants learn to use the robot with a …

This study tests whether applying kinesio tape to the neck muscles can improve swallowing safety in people who have trouble swallowing after a stroke. Researchers will measure changes in swallowing using a special X-ray video before and right after the tape is applied. The study …

This study tests if adding dance therapy to standard physical therapy helps people with chronic stroke (at least 6 months after) improve their balance and walking. Sixteen participants will be split into two groups: one gets standard therapy plus dance, the other only standard th…

Researchers at the University of Washington are testing whether combining non-invasive spinal stimulation with an ankle exoskeleton can improve walking in people with neurologic conditions such as cerebral palsy, stroke, and premature birth. The study includes up to 10 participan…

Researchers test whether an 8-session dance workshop improves balance in adults with hemiparesis, a weakness on one side of the body. Participants are randomly assigned to either the dance program or an upper-limb rehabilitation program. The study measures changes in walking and …

Researchers are testing a 12-week home-based programme that combines aerobic exercise, strength training, stretching, and self-management education for people who had a stroke more than six months earlier. The trial enrolls 30 community-dwelling survivors aged 20 to 59 who can wa…

Researchers are testing whether a dual-task exercise program helps stroke survivors walk while doing a mental task. The study compares dual-task training, which combines walking with cognitive activities, to single-task training, where walking and thinking are practiced separatel…

This study tests whether playing specially designed, AI-powered games can improve thinking skills and arm/hand function in people who have had a stroke. Forty adults aged 45-60 with mild memory or thinking problems after a stroke will use a smartphone app and motion-sensing games…

This study tests whether dry needling (inserting thin needles into tight muscles) can reduce spasticity—stiffness that makes movement hard—in people who have had a stroke. About 28 adults who can walk independently will receive either real or sham (fake) needling once a week for …

This trial tests a support package called CaknaStrok for people caring for a family member who just had a stroke. The package includes a mobile app with videos and tools, plus a guidebook, all tailored for Malaysian caregivers. Researchers compare caregivers who get the package w…

This study tests whether special knee strengthening exercises can improve balance and body awareness (proprioception) in people who had a stroke. About 34 participants who had a stroke 3 months to 1 year ago will do either isokinetic knee exercises or standard rehab. The goal is …

This study tests a remote program called teleABLE that helps people who had a stroke within the past year reduce their sitting time. Participants either get 12 behavioral coaching sessions or 6 health education sessions. The goal is to see if the program improves quality of life …

Researchers are testing whether an electromyography-controlled functional electrical stimulator (FitFES) helps stroke survivors regain arm and hand function. The device reads muscle signals and delivers electrical stimulation during task-oriented exercises. Fifty adults who had a…

Researchers want to know if a wireless peripheral nerve stimulator, already implanted in some patients for chronic arm pain, can also make paralyzed muscles contract. The trial enrolls adults with stroke or spinal cord injury who have the device on nerves in the arm. Participants…

This study tests whether balance training guided by artificial intelligence can improve pelvic alignment and reduce fall risk in people who have had a stroke. Thirty-eight stroke survivors will wear sensors and perform static and dynamic balance exercises. The AI adjusts the exer…

Stroke often damages trunk control, balance and walking ability. Researchers are testing whether combining transcranial direct current stimulation, a mild electrical current applied to the scalp, with pelvic proprioceptive neuromuscular facilitation, a hands-on stretching and mov…

This study is testing a robotic lower-limb exoskeleton combined with functional electrical stimulation (FES) to help people with conditions like spinal cord injury, brain injury, or multiple sclerosis improve their walking. The device provides robotic support and electrical stimu…

This study tests a rehabilitation method called modified constraint-induced movement therapy (mCIMT) for people recovering from a stroke. Participants wear a mitten on their unaffected arm for several hours a day while practicing tasks with the affected arm. The goal is to see if…

This study tests whether wearable sensors and goal-setting sessions with a physiotherapist can help stroke survivors stay active after leaving inpatient rehabilitation. Participants wear sensors to track activity, sleep, and sedentary behavior, and some receive feedback and set g…

This study tests whether early, intensive leg exercises, done by a physical therapist and a parent together, can improve walking and motor skills in children aged 8 months to 3 years who had a stroke around birth. The study compares this approach to usual care. The goal is to see…

This trial tests whether virtual reality (VR) relaxation sessions can reduce agitation in people who recently had a stroke. Participants are randomly assigned to receive either standard stroke care plus VR sessions or standard care alone. Researchers measure agitation levels and …

This trial tests whether an 8-week occupational therapy program can help stroke survivors improve their ability to perform everyday tasks and adopt healthier habits. Participants are randomly assigned to either a psychosocial support group or a group focused on instrumental activ…

This study tests a new rehabilitation program for people with arm weakness after a stroke. Participants rotate through four workstations: listening to audio-guided mental practice, playing virtual reality games, watching action videos, and physically practicing arm tasks. The goa…

This study tests whether acceptance and commitment therapy (ACT), delivered via online video calls, can help stroke survivors adjust emotionally. Five adults who had a stroke over three months ago will attend weekly 90-minute group sessions for eight weeks. Researchers will track…

This study tests whether a virtual reality (VR) system called MAGIC-GLASS is usable and acceptable for stroke survivors to use at home as part of their rehabilitation. Participants wear a headset that shows virtual hands responding to their own movements, and they play mini-games…

This study tests whether intensive robotic arm training can help people recovering from a stroke improve arm movement and reduce stiffness. Participants will use two types of robotic devices in 12 sessions over four weeks. Researchers will also use a technique called muscle syner…

This study tests whether pairing a mild electrical stimulation to the ear with arm exercises can improve motor recovery in people who had a stroke at least six months ago. Participants will do task-specific training at home three times a week for two weeks, with the ear stimulati…

This trial explores whether exposure to artificial light that mimics natural sunlight can improve brain activity, heart rate regulation, and movement in people who have had a stroke. Thirty chronic stroke survivors will undergo light sessions while their brain waves and heart rhy…

This trial tests whether adding music therapy to standard rehabilitation helps people recover better after serious neurological injuries like stroke, brain injury, or spinal cord damage. About 75 participants aged 16-80 will be randomly assigned to receive either music therapy or…

This study tests whether walking to a metronome beat—called rhythmic auditory stimulation—can help people who have had a stroke walk farther and with a more steady, automatic gait. It will also see if older adults without stroke show similar benefits. Participants will complete t…

This pilot study is testing whether a low-cost, portable driving simulator can help retrain driving skills in people who have had a stroke or who live with Parkinson's disease or multiple sclerosis. Participants will be randomly assigned to train on either the portable simulator …

This trial tests whether auricular acupuncture—using tiny needles on specific ear points—can ease constipation in hospitalized stroke patients. Participants receive either real ear acupuncture or a sham version, alongside standard care, for eight daily sessions. Researchers will …

This study tests whether combining kinesiotaping (a specialized tape applied to the skin) with a steroid injection into the shoulder can reduce pain and improve arm function in people who have had a stroke and experience shoulder pain on one side. Participants will receive the co…

This study tests a new therapy that uses moving sounds to help stroke survivors with spatial neglect — a condition where they ignore one side of space. 18 participants will either get standard rehab or standard rehab plus dynamic auditory cueing for 4 weeks. The goal is to see if…

Many stroke survivors are left with a stiff, hard-to-move arm due to spastic cocontractions—muscles that contract at the wrong time. This small study tests whether injecting botulinum toxin A into the elbow flexor muscles can reduce those cocontractions and improve active arm mov…

This study tests whether health education videos redesigned using semiotics—the science of signs and symbols—can help stroke survivors improve daily activities, sleep, anxiety, and depression. Two hundred stroke patients will be randomly assigned to watch either these optimized v…

This study tested a soft robotic glove called EsoGLOVE to help stroke patients improve hand movement and strength during inpatient rehab. 61 stroke survivors used the glove for at least 30 minutes a day, five days a week, for three weeks. The goal was to see if the glove could as…

This pilot study tests whether a type of non-invasive brain stimulation called accelerated repetitive transcranial magnetic stimulation (rTMS) can safely reduce apathy in people who have had a stroke. Apathy — a lack of motivation or interest — is common after stroke and can hind…

This study tests whether a home-based occupational therapy program using video calls and activity monitoring can help older stroke survivors improve their daily functioning and self-management. Researchers will compare this approach to standard care in 171 participants over 26 we…

This completed trial tested whether brief, moderate-to-vigorous physical activity sessions combined with health education could increase exercise in stroke survivors. 36 adults aged 50 and older who had a stroke and lived at home took part. Participants wore an accelerometer to t…

This study tests whether balance exercises that challenge the senses (like closing eyes or standing on uneven surfaces) can improve balance and reduce fall risk in people who had a stroke over 6 months ago. 46 participants will be split into two groups: one doing these special ex…

This study tested whether fast arm movement training helps people who had a stroke regain arm function better than standard accuracy training. 44 chronic stroke survivors with mild to moderate arm weakness participated. The training focused on moving quickly, and researchers meas…

This study tested whether adding virtual reality-based mirror therapy or electrical stimulation-assisted cycling to standard rehab helps stroke survivors regain arm function better than rehab alone. Sixty adults who had a stroke within the past six months took part in a four-week…

This pilot study tests a home-based rehabilitation program called TASSRET for stroke survivors who have limited access to physiotherapy. Fifty participants will use either a video or a manual guide to practice specific tasks aimed at improving arm and leg function, balance, and q…

This study tested whether adding mental practice of swallowing to standard therapy helps people who have trouble swallowing after a stroke. 43 adults were split into three groups: one watched swallowing videos then imagined the action, one just imagined swallowing, and one had on…

This study tested a new occupational therapy program called PRO-MAMA for older mothers (70+) who have had a stroke. The program focuses on helping them take part in meaningful activities related to their role as a mother. Fourteen women completed the program, and researchers meas…

This study tested a new occupational therapy called HABIT, designed to help stroke survivors use their affected hand more in everyday activities. Eleven adults with mild hand weakness after stroke participated. Researchers measured hand use and satisfaction with daily tasks befor…

This study compared two non-invasive therapies—radiofrequency (TECAR) and ultrasound—for treating shoulder pain in 45 stroke survivors. Participants had shoulder pain for at least 3 months after their stroke. Researchers measured pain, range of motion, and daily function to see w…

This study tested whether wearing a pressure splint on the leg during rehab exercises helps stroke patients with one-sided weakness (hemiplegia) improve leg movement, balance, and strength. Thirty participants were split into two groups: one did exercises with the splint, the oth…

This study looked at how two types of arm exercises—open and closed kinetic chain activities—affect muscle tightness and hand skill in people who had a stroke. Thirty stroke survivors with arm weakness did one type of exercise, and their muscle stiffness and dexterity were measur…

This study tested a nurse-led home care guide for stroke patients to help with daily activities. The goal was to see if the guide could reduce the burden on caregivers and improve their quality of life. The study involved 60 caregivers of stroke patients who were cared for at hom…

This completed study tested whether combining a gentle brain stimulation technique (HD-tDCS) with virtual reality therapy could help people who had a stroke more than three months ago recover arm function. Fifty-eight participants received either real or sham stimulation during V…

This study tested a personalized brain stimulation technique called iTBS to help people with long-term thinking and memory problems after a stroke. Sixty participants received either real or sham stimulation over three weeks. The goal was to see if this approach could safely impr…

This study tested a mobile robot designed to help people who have had a stroke regain their ability to walk. 37 stroke survivors used the robot for 16 sessions along with their usual physical therapy. The goal was to see if the robot improved their balance and walking more than s…

This study tested two different therapies—mirror therapy and action observation therapy—to see which better helps chronic stroke survivors improve arm movement and quality of life. 76 participants received one of the therapies plus standard physiotherapy for six weeks. The goal i…

This study tested whether a 24-session program of functional electrical stimulation (FES) on the tibial nerve could improve walking in people who had a stroke more than a year ago. Fifteen participants with chronic stroke and leg weakness were enrolled. The main goal was to see i…

This study tested whether a nature-based walking program called GREEN Walk can improve quality of life for people who have had a stroke. Eleven chronic stroke survivors took part in 60-minute sessions walking on grass, slopes, and uneven ground to mimic real-world movement. Resea…

This study tested whether combining somatotherapy (body awareness and movement exercises) with occupational therapy (training in daily tasks like dressing and cooking) could improve cognitive function in 50 adults who had a stroke. Participants received 35-minute sessions five da…

This study looked at whether electroacupuncture (a type of acupuncture with mild electric pulses) can lower inflammation and help people recover after a stroke. 17 adults who had their first ischemic stroke took part. Researchers measured changes in symptoms and blood markers to …

This study tested whether a chin tuck against resistance (CTAR) exercise can improve swallowing in stroke patients with dysphagia. 112 participants did the exercise daily for two weeks alongside standard rehab. Researchers measured swallowing ability with a water test and a quali…

This early-stage trial tested a new oral drug called MTR-601 in 89 healthy adults to see if it is safe and how the body processes it. The drug aims to reduce muscle stiffness and spasms, which could help people with conditions like cerebral palsy, multiple sclerosis, or stroke. S…

This study tested whether adding gentle sensory stimulation (like light touch and tapping) to standard physical therapy could improve facial symmetry and function in people with facial palsy after a stroke. Thirty-six participants were split into two groups: one received both sen…

This study tested two therapies—mirror therapy and PNF techniques—to see if they improve leg movement and balance in people who had a subacute stroke. 36 participants aged 40-65 were split into two groups, each receiving one therapy along with standard exercises. The goal was to …

This pilot study tested a wearable grasping neuroprosthesis in 6 people with hand weakness after a stroke. Participants used the device at home daily to help with gripping tasks. The study focused on how often people used it and whether it was practical and helpful in real life.

This study looked at 39 adults who had arm stiffness (spasticity) after a stroke. Researchers compared different types of transcranial magnetic stimulation (TMS) combined with Botox injections to see which worked best. The goal was to reduce muscle tightness and improve arm movem…

This study tested a device that gently stimulates nerves in the head and neck to help people who had a stroke move their arm better. Sixteen adults who had a stroke at least six months ago used the device during rehabilitation. The goal was to see if the device is safe and if it …

This study tested whether combining intense arm training with electrical muscle stimulation and brain stimulation could improve arm function in 20 chronic stroke survivors who had severe hand paralysis for more than 6 months. Participants received both types of brain stimulation …

This study tested whether a gentle brain stimulation technique called tDCS, combined with health education and aerobic exercise, can help reduce fatigue in people who have had a stroke. 54 participants who had a first stroke within the past 45 days and reported significant fatigu…

This study tested a new walking therapy for people who had a stroke at least 6 months ago. A robotic device was used to amplify the person's own leg movements during walking, aiming to improve balance. 33 participants completed the training, and researchers measured changes in wa…

This study tested whether using a mirror to create the illusion of movement in a paralyzed arm can improve function in people who had a stroke within the past month. 49 participants were split into three groups: one did mirror therapy with only the good arm moving, another moved …

This study tested three types of hand exercises in 81 people who had a stroke: sensory exercises, motor exercises, and a combination of both. The goal was to see which approach best improved hand strength, dexterity, and reaction time. Results suggest that combining sensory and m…

This study tested whether a virtual reality shopping game could help stroke survivors improve their daily living skills. Twenty-nine adults who had a stroke 1 to 18 months earlier participated. One group practiced shopping in a virtual supermarket, while the other did standard co…

This study tested whether a breathing exercise using an Ambu-bag (air stacking) can improve lung function and trunk control in people who had a stroke. Twenty stroke survivors did either the air stacking breathing exercise or standard diaphragmatic breathing, three times a week f…

This study tested two non-drug therapies—graded motor imagery (mental rehearsal) and mirror therapy (using a mirror to trick the brain)—in 44 chronic stroke patients aged 45 to 65. The goal was to see which better reduces muscle spasticity and improves independence. Both therapie…

This study tested whether stroke survivors could use non-immersive virtual reality exercises at home to improve arm function and balance. Twenty-seven people with chronic stroke (more than 6 months since their stroke) participated in an 8-week program. The exercises were designed…

This pilot study tested whether adding virtual reality (VR) exercises to standard rehabilitation helps people who recently had a stroke recover their thinking skills and ability to do daily tasks. Thirty-six adults with acute stroke and mild cognitive impairment were assigned to …

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…

This study tested whether combining focal muscle vibration (gentle muscle shaking) with transcranial direct current stimulation (a mild brain current) could help stroke survivors move better and reduce muscle tightness. Sixty people with chronic stroke received these treatments a…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS could reduce depression and improve thinking in people who had a stroke. Sixty participants received either tDCS or breathing exercises over eight weeks. The goal was to see if tDCS could be …

This study tested whether adding functional electrical stimulation (FES)-assisted cycling to standard rehab helps stroke survivors with Complex Regional Pain Syndrome (CRPS). Forty participants either received FES cycling plus conventional therapy or conventional therapy alone fo…

This study tested a simple, non-invasive procedure called ischemic conditioning in 132 chronic stroke survivors. The procedure involves inflating a blood pressure cuff on the affected leg to briefly stop blood flow, then releasing it, repeated several times. Researchers measured …

This study tested whether a device that assists hand opening and a robot that supports the shoulder can help stroke survivors with moderate to severe arm weakness practice daily activities. 53 participants completed the trial. The goal was to see if this device-assisted practice …

This study tested a gentle, non-invasive brain stimulation technique called tDCS in 14 people who had a stroke at least a year ago and still have trouble finding words (aphasia). The goal was to see if stimulating a key language area could improve their ability to name pictures a…

This study tested low-level laser therapy (LLLT) on 18 chronic stroke patients with ankle stiffness. Half got laser plus physiotherapy, half got physiotherapy alone for three weeks. Both groups improved, but the laser group had greater reductions in muscle tightness and better wa…

This study looked at whether adding robot-assisted walking training to stationary cycling helps people who recently had a stroke and are losing muscle. 53 participants did either cycling alone or cycling plus robot walking for 4 weeks. The goal was to see if the combination impro…

This study tested whether a set of exercises called FAST (Fast muscle Activation and Stepping Training) can improve walking balance in people who had a stroke. 55 participants who had a first stroke within the past 6 months and had leg weakness took part. They did 12 sessions of …

This study tested whether 3 weeks of intensive language therapy (at least 2 hours daily, 5 days a week) helps people with long-term aphasia after a stroke communicate better in everyday situations. 156 participants with aphasia for at least 6 months were assigned to either immedi…

This study looked at whether using magnetic stimulation on the arm before a specific type of physical therapy helps people who had a stroke regain better use of their affected arm and hand. 50 participants were included. The approach aims to improve wrist movement and daily activ…

This study tested whether adding seated vibration training to standard rehab could help people who had a stroke at least six months earlier. Over four weeks, 39 participants received vibration training plus usual care. Results showed improvements in leg strength on the unaffected…

This study tested whether playing virtual reality games could help people who had a stroke more than 6 months ago improve arm movement. 15 chronic stroke patients with arm weakness participated. They used a head-mounted VR device to do exercises. The goal was to see if this fun, …

This study tested a powered hip exoskeleton for gait training in 32 people who had a stroke at least 3 months earlier. Participants used the device for 10 sessions over 5 weeks. The main goal was to check safety and see if walking speed improved.

This study tested whether vibration training can help people who recently had a stroke improve leg muscle strength, daily function, and mood. 148 patients took part. The approach uses whole-body vibration to stimulate muscles, aiming to speed recovery after a stroke.

This small pilot study tested whether a brain-computer interface (BCI) that gives real-time feedback during mental practice could improve arm function in people who had a stroke at least a year ago. Seven participants did mental imagery exercises with or without real brainwave fe…

This study tested a device called MyoRegulator® to see if it can reduce muscle stiffness (spasticity) in the lower leg after a stroke. 44 adults who had a stroke at least 6 months earlier took part. Half received real treatment and half received a sham (fake) treatment for 5 days…

This study tested whether robot-assisted arm therapy works as well as traditional therapy with a physiotherapist for people recovering from a stroke. 58 adults who had a stroke within the past 6 weeks took part in a 6-week program doing the same arm exercises, either with a robot…

This study tested the safety and effectiveness of repeated MYOBLOC injections over one year in 187 adults with troublesome drooling caused by conditions like Parkinson's disease, stroke, or ALS. Participants received up to four treatment sessions, and researchers tracked side eff…

This Phase 3 study tested whether injections of MYOBLOC (a botulinum toxin type B) into the salivary glands can safely reduce troublesome drooling in adults. 187 participants received either MYOBLOC or a placebo. The main goals were to measure changes in saliva flow and overall i…

This study tested whether a non-immersive virtual reality system (MindMotion GO) could help people with chronic stroke improve arm function better than standard occupational therapy. Twenty-six adults who had a stroke more than 6 months ago participated in 8 weeks of training. Th…

This study tested a new program called CATCHES for people who had a stroke and are afraid of falling. The program combines physical therapy at home with coaching to reduce fear. 30 adults who had a mild to moderate stroke took part. The goal was to see if the program is practical…

This study tested a tablet-based app that helps people recovering from stroke improve coordination between both arms. 40 participants with moderate arm weakness used the app to practice moving their arms together in rhythm. The goal was to see if this fun, at-home style training …

This study tested a device called recoveriX that uses a brain-computer interface, electrical stimulation, and virtual reality to help stroke survivors improve their walking. Thirty participants who had a stroke at least six months ago were split into two groups: one used the full…

This study tested a device called IpsiHand that helps people who had a stroke regain movement in their arm and hand. The device reads brain waves through a special cap and moves the hand using a robotic brace. 24 stroke survivors used it for 12 weeks to see if it improved their m…

This study tested whether mirror therapy can reduce pain and improve movement in stroke patients who also have complex regional pain syndrome (CRPS). Forty adults who had a stroke within the past year and were diagnosed with CRPS took part. They received either real mirror therap…

This study tested two methods to help people regain arm movement after a stroke: looking at a mirror to trick the brain, or using a robotic hand glove that mimics the healthy arm. Thirty adults who had a stroke within the past year took part. Both groups also received standard ph…

This study tested whether adding a drug called Cytoflavin to standard physical rehab helps stroke survivors recover better. Cytoflavin is an antioxidant that may protect brain cells and improve learning of new skills. The trial involved 240 adults aged 40-80 who had a stroke 2 we…

This study tested whether combining neuromuscular electrical stimulation (gentle electrical pulses to muscles) with task-oriented training (practicing everyday movements) could improve arm and hand function in stroke survivors. 45 people who had a stroke 6 to 24 months earlier to…

This study tested whether people with spinal cord injuries can reach a high-intensity heart rate while walking in a robotic exoskeleton. Eleven participants completed five training sessions using the Ekso device. Researchers measured heart rate, walking speed, and endurance befor…

This study tested a non-invasive treatment called shock wave therapy on 21 stroke survivors with arm stiffness. The therapy uses sound waves to relax tight muscles. Participants received 8 sessions over 4 weeks, and researchers checked for improvements in stiffness, pain, and dai…

This study tested a myoelectric computer interface (MyCI) in 35 stroke survivors to reduce abnormal muscle co-activation. Participants trained with the device in a lab setting. The goal was to improve arm function and reduce muscle tightness. Results may help develop new therapie…

This study tested whether a robotic exoskeleton called Ekso can help stroke patients improve their walking and balance during early inpatient rehabilitation. Forty adults who had a stroke were randomly assigned to receive either Ekso-assisted gait training or conventional therapy…

This study tested whether combining motor imagery (thinking about moving without actually moving) with a type of brain stimulation called TMS could help people who had a stroke regain arm function. 24 adults who had a stroke at least one month prior participated. The goal was to …

This study tested whether combining a non-invasive brain stimulation technique called transcranial magnetic stimulation (TMS) with balance exercises could improve walking in people who had a stroke. Thirty stroke survivors, aged 50 to 60, participated. Researchers measured change…

This small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve naming ability in 11 people with chronic aphasia after a stroke. Participants received either real or sham stimulation during language training over two weeks. The goal was…

This study tested whether a 15-minute session of rhythmic beats (like a metronome) before standard physiotherapy could improve balance and weight shifting in stroke patients. 27 participants were split into two groups: one received the beats plus usual therapy, the other only usu…

This study tested whether specialized sexual nursing care could help stroke patients and their partners manage sexual difficulties. Thirty stroke survivors and their partners were split into two groups: one received personalized counseling and education from trained nurses, while…

This study looked at whether starting more frequent or intense physical therapy within the first day after a stroke helps patients regain movement and balance. 102 adults with acute stroke were split into groups receiving standard care, more sessions, harder exercises, or both. R…

This study tested whether a device that sends magnetic pulses to shoulder muscles can help stroke patients with a dislocated shoulder. Twenty people in the subacute phase of stroke received either real or fake magnetic stimulation for 20 minutes a day, 5 days a week, for 2 weeks,…

This study looked at whether listening to self-chosen Italian music during and after a stroke hospital stay can improve mood, reduce anxiety and depression, and boost overall well-being. 150 stroke patients were randomly assigned to either regular music listening or standard care…

This study tested whether using a video game called MindPod Dolphin is safe and practical for arm rehabilitation in people who recently had a stroke. 58 participants played the game, controlling a dolphin with their affected arm. The goal was to see if patients would stick with i…

This study tested whether combining a drug called galantamine with a specific cognitive training program could improve thinking skills in adults aged 35-70 who had a first stroke 3 months earlier. 47 participants received either the drug or a placebo, plus brain training, and wer…

This study tested two ways to do extra arm exercises after a stroke: a custom program designed by a therapist, or using a special movable wheelchair armrest (called Boost). 35 people in acute rehab took part. The goal was to see which method better improves arm movement and reduc…

This completed study tested the EXOPULSE Mollii suit, a full-body garment with 58 electrodes, in 30 stroke survivors who had muscle stiffness (spasticity) and balance problems. The suit stimulates muscles to reduce spasticity and improve balance. Researchers measured balance chan…

This study looked at whether adding a 15-minute vibration treatment to a standard arm skill program helps people who had a stroke 3-6 months ago. 60 participants were split into two groups: one got the vibration plus training, the other got training alone. Researchers measured ar…

This study tested two non-invasive treatments—high-intensity laser therapy (HILT) and extracorporeal shock wave therapy (ESWT)—to reduce calf muscle stiffness and improve walking in 39 people who had a stroke at least three months earlier. Both therapies aim to relax spastic musc…

This study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…

This study tested an intensive motor rehabilitation program that uses advanced technology to help adults with chronic stroke or spinal cord injury improve their daily functioning. 102 participants were randomly assigned to either the tech-enhanced rehab or a control group. The go…

This study tested whether intensive upper limb rehabilitation helps people who had a stroke at least 6 months ago. 105 participants were randomly assigned to one of two intensive therapy programs or usual care. The goal was to see if high-dose training improves arm movement and f…

This study tested whether combining two physical therapies—extracorporeal shockwave therapy and cryoflow (cold) therapy—can reduce shoulder pain and spasticity in stroke survivors with rotator cuff tendonitis. Thirty participants received either one therapy alone or both together…

This study tested whether the time gap between two types of brain stimulation affects arm and hand recovery in people with chronic stroke. 62 participants received either a short or long interval between inhibitory and excitatory stimulation, followed by robot-assisted arm traini…

This pilot study tested a wearable robotic arm device (NESM-α) in 7 stroke survivors to see if it is safe and feasible for rehab. The robot adjusts to each person's ability, providing gentle assistance during movement. The main goals were to check for side effects and see if pati…

This study tested a problem-solving program delivered by phone and online for Spanish-speaking caregivers of veterans who had a stroke. The program taught caregivers the COPE model (Creativity, Optimism, Planning, Expert Advice) to help them manage caregiving challenges. Research…

This study tested two types of arm exercises in 26 people who had a stroke and had trouble using one arm. One type used automatic movements (where the target moves to guide the arm), and the other used intentional movements (where the target stays still). The goal was to see whic…

This study tested a new device called Miraπ that physically moves a stroke patient's affected hand during mirror therapy. It compared this device to standard mirror therapy in 24 stroke patients with one-sided hand paralysis and pain. The goal was to see if the device could impro…

This study tested whether adding virtual reality (VR) exercises to standard physical therapy helps people who recently had a stroke recover arm and hand function better than therapy alone. Fifty-two adults with a first-time stroke and some remaining arm movement took part. Resear…

This study tested whether a specially designed occupational therapy program could help people with mild-to-moderate thinking problems after a stroke perform daily activities like dressing or cooking. Only 8 people took part, and the goal was to see if the therapy was practical to…

This study tested a device that uses mild electrical pulses to stimulate finger muscles in stroke survivors who cannot open their hand. The goal was to see if it helps them grasp, move, and release objects like a glass or spoon. Eleven people with chronic stroke participated, and…

This study tested whether giving a very high dose of lovastatin (a common cholesterol drug) for 3 days after a stroke is safe. 162 stroke patients received either the high-dose drug or a placebo within 24 hours of symptoms. The main goal was to check for liver or muscle damage, w…

This study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting i…

This study tested a 12-week exercise program set to music for adults with physical disabilities like spinal cord injury, stroke, or Parkinson's disease. Participants exercised three times a week via video calls, doing movements adapted to their ability. The goal was to see if the…

This study tested a 'wisdom enhancement' technique added to standard therapy for depression after a stroke. Three stroke survivors tracked their mood, identity, self-esteem, and wisdom daily. The goal was to see if this approach could improve emotional well-being, but the very sm…

This small study tested whether adding functional massage to eccentric exercises (like slow squatting) helps reduce muscle stiffness and improve leg movement in people who had a stroke at least 6 months ago. Eight adults participated, and the treatment was done at a university cl…

This study tested whether wearing a virtual reality headset during botulinum toxin injections could lower stress and pain in adults with muscle spasticity. Forty-two participants chose calming audio-visual content while getting their shots. Researchers measured heart rate variabi…

This completed study tested whether a new type of electrical stimulation, called spatially distributed sequential stimulation, works better than standard stimulation for people with upper motor neuron disease. Ten adults with stable symptoms used both methods while cycling. Resea…

This study tested whether wearing a weighted brace on the unaffected ankle for three months helps people who have had a stroke walk farther. Forty-two participants who had a stroke more than three months ago but less than five years ago took part. Half wore a weighted brace (2-4 …

This study tested whether an online cognitive behavioural therapy program called Sleepio could improve sleep in people who have had a stroke. 86 chronic stroke survivors were randomly assigned to either use Sleepio for 6 weeks or receive a leaflet with basic sleep tips. The main …

This completed study looked at insurance claims data from 70,000 people with type 2 diabetes and established heart disease to compare the heart-related risks of three diabetes drugs: tirzepatide, dulaglutide, and semaglutide. The goal was to see if any of these drugs was linked t…

This completed study looked at how brain lesions from strokes impact cognitive control—the ability to focus, switch tasks, and make decisions. Researchers tested 184 healthy adults and stroke patients using behavioral tasks, brain scans (MRI), and EEG. The goal was to understand …

This study looked at how stimulating a nerve in the ear (tVNS) affects pupil size in stroke survivors and healthy adults. Researchers compared stimulation on one side versus both sides to see which causes a bigger pupil response. The goal is to use pupil changes as a guide for pe…

This study used a non-invasive brain stimulation technique called TMS to measure how the motor cortex responds in people who have had a stroke. Researchers compared brain excitability between 24 stroke survivors and healthy individuals. The goal was to better understand how strok…

This study tested two advanced rehabilitation devices—a treadmill and an overground walking trainer—to help 80 stroke patients regain their ability to walk. Participants used either the C-Mill treadmill or the Andago overground device alongside standard therapy. The goal was to s…

This study follows 140 working-age stroke survivors in France to find out what factors help or hinder their return to work. Researchers will look at medical details, personal beliefs, and job-related issues. The goal is to create better support plans for people recovering from a …

Researchers at the University of Ioannina are studying stroke patients who have both movement and vision problems. They will evaluate each patient twice, once shortly after the stroke and again weeks later, to measure how these deficits change. The goal is to see whether improvem…

This study looked at how fast treadmill walking, with or without a small electrical stimulation to the ankle muscles, helps people who have had a stroke walk better. Fifty-five participants who were at least six months past their stroke took part. The goal was to understand the b…

This study looks at how nerve reflexes in the thigh muscle affect walking in people who have had a stroke and have a stiff-knee gait. Researchers will use mild electrical stimulation to measure reflex activity while participants walk. The goal is to better understand why some str…

This study looked at 886 adults with suspected traumatic brain injury to better understand how the brain changes after injury. Participants had MRI scans, blood tests, and thinking tests within 48 hours of injury, with optional follow-ups up to a year. The goal was to find better…

This study tests whether a practice resource called PReDAS helps occupational therapists who work with stroke patients feel more confident and make better decisions about driving. Eight occupational therapists on acute stroke units will receive the resource and a one-hour trainin…

This study looked at 20 people with CADASIL, a rare genetic disease that damages brain arteries and causes migraines, strokes, and dementia. Researchers used blood tests, skin biopsies, eye exams, and brain scans to learn more about how the disease works. The goal was to better u…

This trial is testing whether an artificial intelligence (AI) tool can accurately predict how patients with acute ischemic stroke will recover. The AI analyzes patient data in real time to forecast outcomes, such as functional disability, which is then compared with the actual ou…

This study looks at how a stroke affects the jaw joint and chewing muscles. Researchers will use ultrasound to measure jaw structures in 70 stroke survivors and see if these measurements relate to their recovery. The goal is to better understand jaw problems after a stroke, which…

This completed study looked at how a person's total daily-life exposure—called the 'exposome'—affects health after a stroke. Researchers tracked 150 stroke survivors, measuring biological, environmental, social, and lifestyle factors alongside motor and cognitive tests. The goal …

This study tests whether a specialized training program called off-script diagnosis and differential diagnosis (D&D) training can improve neurology residents' ability to diagnose and manage acute ischemic stroke. The training focuses on structured analysis of stroke causes, mimic…

This study tests four different ways to encourage parents to register their children for FAST Heroes, a school-based program that teaches kids and families to recognize stroke symptoms and act fast. The approaches range from a printed letter sent home to an email combined with te…

This study looks back at medical records of people with severe spontaneous brain bleeding (intracerebral hemorrhage) to see if vital signs measured before arriving at the hospital—like blood pressure and heart rate—are linked to recovery and survival six months later. The goal is…

This study looks at whether people who have paralysis on one side after a stroke also have hidden nerve problems in their arms or legs. Researchers will use nerve tests and movement assessments to see how common these nerve issues are and whether they relate to how well a person …

This study investigates how brain activity changes when people imagine moving their wrist. Researchers will use advanced brain scans (MRI and MEG) to create personalized models of these signals, then test if they can decode imagined movements using simpler EEG recordings. The goa…

This study investigates how loss of sensation in the foot and uneven weight distribution between legs affect posture, balance, and walking in people who had a stroke at least six months ago. Researchers will measure foot sensation, joint position sense, and weight-bearing asymmet…

This study uses video-based movement tracking to measure how people walk after a stroke — both in the clinic and at home. Researchers want to see if walking improvements made in therapy actually carry over into everyday life. The study includes stroke survivors and healthy adults…

This study looks at people who have had a stroke to understand which factors — such as muscle stiffness, arm function, thinking skills, and overall physical ability — most affect their ability to take part in daily activities. Researchers will measure these factors and see how th…

This study looks at how young people with conditions like cerebral palsy, spina bifida, and spinal cord injury move from pediatric to adult medical care. Researchers will review medical records from the past 10 years and interview patients who have already made the switch. The go…

This study investigates whether inflammation and stress compounds in the blood are linked to depression after a stroke. Researchers measure inflammatory markers and stress hormones in blood samples from 25 adults who have had an acute ischemic stroke. Participants also complete d…

This observational study investigates fear of falling in adults who have had a stroke. Researchers will assess motor, cognitive, and psychological factors to understand what contributes to this fear. The goal is to help clinicians design better, more personalized rehabilitation s…

This study follows about 800 people undergoing angiographic procedures with redesigned Beacon Tip catheters. The goal is to see if the catheters can be safely navigated to the intended location and used for tasks like releasing contrast dye or taking anatomical measurements. Rese…

This study looks at how certain immune cells (neutrophils) behave in people having a severe stroke. Researchers want to find the best time and target for treatments that block these cells. 440 adults having emergency stroke treatment will give blood samples and have their recover…

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…

This study looks at medical records from France to see how doctors prescribe blood thinners to people with atrial fibrillation (an irregular heartbeat) who also have a high risk of stomach bleeding. The goal is to understand which treatments are used and how often serious bleedin…

This study aims to identify short-term triggers of acute ischemic stroke caused by large vessel occlusion, a severe type of stroke. Researchers will ask 302 patients about their exposure to potential triggers—such as infection, mood changes, smoking, alcohol, diarrhea, and extrem…

This study looked at why some people have trouble balancing while sitting after a stroke. Researchers used a special pressure-sensing pad and motion trackers to measure how 32 stroke survivors shifted their weight and moved their head and trunk. The goal was to better understand …

This study looked at whether brain scans (fMRI) can predict how well stroke survivors will recover arm and hand function after physical therapy. Fourteen people with chronic stroke completed 12 therapy sessions. Researchers measured brain connectivity before and after therapy to …

This study explores whether ultrasound can help evaluate swallowing difficulties in people who have had a stroke. Researchers will measure the size and movement of throat muscles in 52 stroke patients with swallowing problems. The goal is to see if these ultrasound measurements r…

This study tested whether a video call between paramedics and a stroke specialist can help decide the right treatment—like clot-busting drugs or clot removal—before the patient arrives at the hospital. About 215 adults with suspected stroke took part. The goal was to see if remot…

This study looked at over 30,000 adults admitted to hospitals in Maryland to understand why some patients wait in the emergency room even after being admitted (called boarding). Researchers wanted to find out what patient traits lead to longer waits, how boarding increases health…

This study tested whether a wearable sensor (Baiobit®) can reliably measure walking patterns in stroke survivors. Twenty-two adults who had a stroke walked with the sensor on their lower back, and two evaluators compared the results. The goal is to see if this low-cost device can…

This study looked at whether using best-practice physical therapy and giving stroke survivors an activity monitor can help them walk better. About 306 people who had a stroke and were in rehab took part. The main goal was to see if they could walk farther in 6 minutes after the p…

This study tracked 883 adults with atrial fibrillation to see how consistently they took their direct oral anticoagulants (blood thinners). Researchers used pharmacy refill records and a simple questionnaire to measure adherence. The goal was to find patterns that could help iden…

This study tested whether a brain-computer interface (BCI) system, combined with electrical stimulation and virtual reality, can improve arm movement in chronic stroke survivors. Thirty participants were split into three groups, each receiving different combinations of BCI, elect…

This study tested whether a single, one-hour education session using the BEFAST mnemonic (Balance, Eyes, Face, Arm, Speech, Time) could improve stroke patients' knowledge and emergency response. Researchers enrolled 112 hospitalized stroke patients in Malaysia, measuring their kn…

This study tested a training program for 22 caregivers of stroke patients. The program taught basic stroke care, rehabilitation, and self-care. Researchers measured changes in caregiver knowledge, strain, and quality of life before and after the training. The goal was to see if t…

This study tested a new, powerful MRI scan on 56 stroke patients to see if it could detect subtle brain damage not visible on standard scans. The goal was to better understand how much brain tissue is truly saved after treatment. The findings could help doctors predict recovery m…

This study tested whether daily mood check-ins via a mobile app could help predict and prevent depression in people who recently had a stroke. Over 400 participants used the app for three months while researchers tracked their emotional symptoms. The goal was to see if this kind …

This study tested a 4-hour head ultrasound (transcranial-holter) to detect tiny blood clots in people who recently had a stroke. The goal was to see if this test could help doctors find the exact cause of the stroke, which is important for choosing the right treatment to prevent …

This study looked at how activating two key core muscles—the transversus abdominis and lumbar multifidus—affects balance in 36 people with hemiplegia (paralysis on one side) after a stroke. Researchers measured balance using standard tests like the Berg Balance Scale. The goal wa…

This study looked at 150 Caribbean Hispanic adults with heart disease or stroke risk who take the blood thinner clopidogrel. Researchers wanted to see if certain gene variants affect how well the drug works. The goal is to understand why some people get less benefit and to pave t…

This completed study looked at how rising temperatures affect people with chronic conditions like heart disease, diabetes, and depression. Researchers in Germany and Italy surveyed 176 patients to see what symptoms they experienced during heat and what protective steps they took.…

This study tested a wearable device called the MOX activity monitor in 40 older adults (70+) recovering from hip fracture, stroke, or frailty in a hospital rehab ward. The goal was to measure how much they walk, stand, or sit during the day and see if that data helps track recove…

This study looked at 38 people who had a first stroke in the cerebellum, a brain area involved in mood. Researchers used interviews and smartphone tracking to measure depression, anxiety, and apathy in daily life. The goal was to better understand how these mood problems develop …

This study tested whether a gentle, non-invasive brain stimulation technique called tACS could improve hand function in 20 stroke survivors. The stimulation targeted two key brain areas involved in movement planning. Researchers measured brain connectivity and hand movement patte…

This completed study followed 550 people who had a stroke within the last 48 hours. Researchers wanted to understand why some patients recover better than others by looking at their medical history, lifestyle, and blood markers. The goal is to find out what factors protect the br…

This study tested whether an online training program can effectively teach healthcare workers to screen stroke patients for swallowing problems (dysphagia). Swallowing difficulties affect about 55% of stroke patients and increase pneumonia risk. The study involved 82 healthcare p…

This study looked at how well an augmented reality app (Rehabilitation Gaming System) can mimic standard therapy exercises for arm movement after a stroke. 28 people (16 healthy older adults and 12 stroke survivors) performed both therapy exercises and app-based games while weari…

This study translated the Fugl-Meyer assessment, a test that measures movement and function after a stroke, into Turkish and checked if it works correctly. Researchers tested 80 stroke patients in Turkey to see if the Turkish version is reliable and accurate. The goal was to give…

This study looked at how a stroke survivor's sense of body position (proprioception) relates to their walking, balance, and reaction time. Researchers tested 132 first-time stroke patients and compared them to healthy volunteers using standard tests and rehabilitation robots. The…

This study asked stroke survivors, caregivers, and healthcare professionals what they need from a home-based rehabilitation system called NEST. The system includes an exercise app, a smartwatch, and a virtual coach. Researchers held focus groups and interviews in Italy, Spain, an…

This study tested a new robotic device called REACTION that combines an exoskeleton and a gait trainer to help people with stroke or spinal cord injury improve walking and balance. Seven participants completed two sessions of walking and balance tasks, followed by an interview. T…

This study tested different levels of stiffness in custom ankle braces for 40 people who had a stroke. The goal was to find the best brace for each person and create simple guidelines that doctors and therapists can use to prescribe the right brace. Participants walked with five …

This study tested whether a mobile app-based speech therapy program is practical for stroke survivors with mild to moderate communication problems. Twenty patients discharged from the hospital used an iPad for therapy at home while waiting for outpatient services. The main goal w…

This study looked at what makes it easier or harder for veteran stroke survivors to do arm and hand exercises at home. Researchers gave surveys about mood, confidence, and sleep, then used a wearable tracker to measure exercise. The goal is to find ways to help people stick with …

This study looked at whether adding a brain MRI and a check by a nerve specialist could help doctors make better treatment decisions for people with a serious heart infection called infectious endocarditis. The infection can cause silent strokes, and the goal was to see if findin…

This study tested whether community education and hospital improvements could increase the use of clot-busting drugs for stroke in Flint, Michigan. Researchers enrolled nearly 6,000 adult stroke patients across three hospitals. The community intervention included workshops, a mus…

This study used wearable accelerometers to measure how much and how intensely 15 stroke survivors moved their affected arm during everyday activities and therapy. The goal was to see if arm use improved over time. No treatment was tested; the study only observed and recorded move…

This study looked at how to improve care for dizzy patients in the emergency department. Over 90,000 adults participated. The goal was to help doctors use proven tests and treatments for common causes of dizziness like BPPV. The study tested new training and tools to make sure pa…

This completed study used ultrasound to look at the shape and structure of spastic muscles in the arms and legs of 80 stroke survivors. The goal was to see if ultrasound can help doctors better understand and measure muscle changes after stroke. The findings may improve how spast…

This study looked at how blood moves through leg muscles in people who have had a stroke compared to healthy adults. Researchers used gentle leg movements and muscle contractions to measure blood flow. The goal was to learn more about why stroke survivors often have reduced exerc…

This study adapted several questionnaires that measure arm and hand function after a stroke into Polish, and checked how reliable and accurate they are. One hundred people who had an ischemic stroke at least six months ago took part. The goal was to give Polish-speaking patients …

This completed study followed 282 first-time stroke patients for six months to see how well they stuck with their rehabilitation exercises. Researchers used a special model to identify different patterns of compliance and what factors—like physical, mental, or social—might predic…

This study looked at how the brains of people with aphasia (a language disorder after stroke) and healthy people work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to…

This study looked at 332 stroke patients to see if general anesthesia or conscious sedation is better during a procedure to remove blood clots from the brain. The goal was to find which method leads to better recovery and fewer complications within the first week. The results cou…

This study looked at whether virtual reality can help stroke survivors who have an uneven walk (one leg takes longer steps than the other). 42 adults who had a stroke at least 3 months ago took part. They learned a new walking task in virtual reality, and researchers measured how…

This study followed 82 people with blocked arteries supplying the back of the brain to see if low blood flow raises the risk of stroke or mini-stroke. Participants had already experienced a stroke or transient ischemic attack (TIA) and had at least 50% blockage in those arteries.…

This study tested whether wrist-worn accelerometers can accurately measure how much stroke patients use their weaker arm during everyday activities like dressing and eating. Twenty-five participants were recorded with both accelerometers and video cameras. The goal was to see if …

This study looked at 55 stroke survivors to see if reducing sitting time early after stroke helps with walking and daily function. Researchers also checked if brain scan markers can predict who benefits most from rehab. The goal is to create personalized recovery plans based on e…

This study tested whether a 1-minute 51-second animated video called FAST BEE helps people learn and remember stroke warning signs. Over 300 healthy adults and teens watched the video and then answered questions about what they learned. The goal was to see if the video improves r…

This study looked at 455 stroke patients to see if a continuous finger blood pressure monitor (Clearsight) or standard arm cuff measurements better predict brain bleeding after clot removal. Each patient had both methods used within 24 hours after treatment. The goal was to see w…

This early study tested whether breathing short bursts of low oxygen (like being on a tall mountain) is safe for people who had a stroke. The idea is that this might trigger the brain to release proteins that help it recover. 16 stroke survivors took part, and the main goal was t…

This study checked how well the Fugl-Meyer Assessment (a test for stroke recovery) works in people recovering from a stroke. Over 100 patients in rehab were tested when they arrived and when they left. The goal was to see if the test accurately tracks improvement.

This study measured muscle loss (sarcopenia) in 80 stroke survivors using simple tests like grip strength, walking speed, and ultrasound. Researchers compared patients who had a stroke recently (post-acute care) with those who had one over a year ago. The goal was to see how age,…

This study looked at 53 stroke survivors to see if fatigue severity is linked to their quality of life. Participants filled out two questionnaires: one about fatigue and one about health-related quality of life. The goal was to understand how much fatigue independently affects we…

This study looked at 29 children with brain injuries to test two new methods for checking how well the brain controls its own blood flow. The goal was to see if these methods could help doctors better understand and treat brain injuries. The study did not test a treatment, but ai…

This completed study looked at how leg muscles work during walking in 500 people who had a stroke. The goal was to understand muscle patterns, test how well current measurement methods work, and find early signs that predict walking recovery. The results could help doctors create…

This study looked at how doing a thinking task while walking affects the brain in people who have had a stroke. Eleven stroke survivors walked on a special mat while a brain scanner measured their brain activity. The goal was to understand why walking gets harder when you have to…

This study tested a program to help people with stroke or TIA transition from hospital to home. 213 participants received either the program or usual care. The program focused on improving communication, health literacy, and medication management. Researchers measured quality of …

This study worked with 49 stroke patients, their families, and healthcare teams to design and test a more personalized way to move from the hospital to home rehabilitation. The goal was to improve the quality of care transitions and health literacy. The study did not test a treat…

This study tested whether home automation and remote monitoring can help elderly people (65+) with multiple chronic conditions live safely at home. Over 500 participants had their homes equipped with sensors that tracked health signs and sent alerts to doctors. The main goal was …

This study tested whether a special MRI scan called IVIM can predict how well people recover three months after an acute ischemic stroke. Researchers added a two-minute scan to the standard MRI for 274 adults admitted with stroke. They then compared the scan results to the patien…

This study looked at 174 adults who had a stroke and were treated under general anesthesia. Researchers compared removing the breathing tube early versus later to see which approach leads to better functional recovery after 90 days. The goal is to find the best time to take patie…

This study looked at 70 family caregivers of stroke patients who also have bladder issues. Researchers measured how much burden, fatigue, poor sleep, and depression caregivers experience. The goal was to understand the challenges these caregivers face, not to test a new treatment…

This completed study tested whether mild electrical stimulation of the outer ear (taVNS) can change how brain regions communicate in people who had a stroke more than 6 months ago, as well as in healthy adults. Researchers used a brain-imaging technique called fNIRS to measure re…

This study looked at 50 people who had a mild stroke to understand why they might struggle with everyday activities like work, hobbies, or socializing. Researchers wanted to see if factors like mood, fatigue, or thinking problems make these gaps worse, and if having more gaps low…

This study looked at brain activity in 64 people (some who had a stroke and some healthy) while they moved their arms with different levels of effort. The goal was to understand how the brain responds during rehabilitation exercises. Researchers used a special brain scanner (fNIR…

This study looked at how the calf muscle and Achilles tendon work together during walking in people who have had a stroke or spinal cord injury, compared to healthy individuals. Researchers used ultrasound and motion analysis to measure muscle and tendon lengths in 64 adults. The…

This study followed 167 people with atrial fibrillation or flutter who had a catheter ablation procedure. Researchers measured changes in stroke and bleeding risk scores before and 3, 6, and 12 months after ablation. They also compared different monitoring methods, including impl…

This first-in-human study tested a new smart guidewire (Clotild®) in 45 stroke patients undergoing emergency clot removal. The wire helps guide the removal tool and also measures the clot's electrical properties to determine its composition. The main goal was to check safety, suc…

This study checked if a Turkish version of the Bolus Residue Scale (BRS) is a reliable way to measure swallowing problems in people who recently had a stroke. Researchers looked at video recordings of 40 patients swallowing and had experts rate the results. The goal was to make s…

This completed study involved over 36,000 patients and aimed to create quality indicators for stroke and chronic coronary syndrome care using French national health databases. Researchers linked patient data from practice registries to the national database to validate these indi…

This study tested a French version of a questionnaire that measures physical activity levels in people with physical disabilities. Fifty participants with conditions like stroke, multiple sclerosis, or Parkinson's disease filled out the questionnaire twice, two weeks apart. The g…

This study looked at whether doing virtual reality exercises with other people (multi-player) is more motivating than doing them alone. It included 86 participants: healthy teens, children with motor disorders, and older adults with conditions like stroke or COPD. Researchers mea…

This study followed 188 children who had seizures shortly after birth to see how they develop over time. Researchers measured thinking skills, behavior, and daily function. The goal is to understand which children are at higher risk for conditions like cerebral palsy or intellect…

This study looked at whether online training can improve how well emergency department doctors interpret CT head scans. 173 clinicians from 6 UK hospitals took part. One group received training early, while a control group got it later. The goal was to see if training boosts accu…

This completed study tested a program to help stroke survivors in rural Kentucky take their blood pressure medications as prescribed. Four participants received one-on-one education and tailored sessions from a pharmacy technician and community health worker. The goal was to see …

This study tested a new way to assess and train balance using a reaching task. Seven people, including stroke survivors and healthy adults, took part. They stood and pointed at a moving target on a screen, which challenged their balance. The goal was to see if this method could s…

This study looked at how different types of exercise (interval vs. continuous) and intensity levels (moderate vs. high) affect aerobic fitness and blood vessel health in people who have had a stroke. 59 participants used a seated stepper that moves both arms and legs. The goal wa…

This study followed 200 stroke patients aged 18 to 64 during inpatient rehabilitation. Researchers checked how well standard tests like the Functional Independence Scale and Mini Mental State Exam describe recovery using the ICF framework. The goal was to understand current monit…

This study reviewed medical records of 274 adults who had emergency surgery for a torn aorta (aortic dissection). Researchers looked at how often patients had brain complications like stroke or coma after surgery and whether those complications led to longer stays in the intensiv…

This study tested a new device called a hybrid neuroprosthesis to help people who have had a stroke move their arm better. 24 adults with arm weakness after a stroke used the device in rehab sessions. The goal was to see if the device was easy to use, safe, and helpful, not to cu…

This study looked at how well the ReVive™ SE device works to restore blood flow in the brain during a stroke. Only one patient took part, and the goal was to see if the device is useful in standard care. The main measure was how much blood flow returned after using the device.

After a stroke, many people can move their affected arm but choose not to, a condition called non-use. This study tested 53 participants (stroke survivors and healthy controls) to see how the need for force or precision affects arm use. Researchers used a weight-support system to…

This study observed 20 stroke patients with hemiplegia (weakness on one side) as they walked 10 meters. Researchers used sensors and a special walkway to measure foot movements and timing. The goal was to gather data that could help improve when functional electrical stimulation …

This completed study followed 229 stroke survivors over time to understand what factors might lead to dementia or cognitive problems after a stroke. Researchers looked at medical history, brain scans, and medications. The goal was to identify clues that could help predict and pos…

This study looked at 40 stroke patients with arm muscle stiffness (spasticity) who were treated with botulinum toxin (Botox). Researchers measured tiny electrical signals in the muscle to see how they change over time and whether they relate to how well the treatment works. The g…

This study used a special eye-imaging technique called adaptive optics to look at tiny blood vessels in the retina of people who recently had a stroke. Researchers compared these images to those from healthy individuals to see if the blood vessel structure differs. The goal was t…

This study looked at 15 stroke patients with a condition called cerebral amyloid angiopathy (CAA), which makes blood vessels in the brain fragile and prone to bleeding. All patients received a clot-busting drug (thrombolysis) and were checked for brain bleeding 24 hours later. Re…

This study tested two types of non-invasive brain stimulation (called paired associative stimulation) to see if they could help improve hand movement in people who had a stroke. 81 participants (60 stroke survivors and 24 healthy volunteers) took part. The main goal was to unders…

This study looked at 206 patients who had carotid artery surgery to see if the hyoid bone (a small bone in the neck) is linked to artery narrowing and stroke. Researchers used CT scans to measure the distance and position between the hyoid bone and the carotid artery. The goal wa…

This study involved 32 adults with arm weakness from stroke, multiple sclerosis, or spinal cord injury. Researchers measured how much force patients could voluntarily produce in their arms and used that data to build mathematical models. The goal is to use these models to improve…

This study looked at brain MRI scans of 122 stroke patients to see if those with a blood clot in the heart (intracardiac thrombus) had different patterns of brain damage compared to those with atrial fibrillation. Researchers analyzed the location, size, and number of stroke lesi…

This completed study followed 633 stroke or TIA survivors in France to understand why some stop taking their secondary prevention medications. Researchers looked at factors like age, beliefs about medicine, and healthcare access. The goal is to improve long-term adherence and pre…

This study looked at how well people think and remember after surgery to clear a blocked neck artery (carotid endarterectomy). About 800 patients took brain tests before and after surgery, and their results were compared to people having spine surgery. The goal was to find out ho…

This study used a special light-based imaging technique called fNIRS to watch how the brain reorganizes itself in the first two months after a stroke. Ten participants who had a stroke 2-4 weeks earlier underwent standard physical and occupational therapy while researchers measur…

This study tested a small, wearable sensor (FOX HiKoB) to measure foot movement in 29 stroke survivors who have foot drop. The goal was to see if the sensor could accurately detect when the foot lifts, which could then trigger electrical stimulation to help lift the foot. The sen…

This pilot study looked at how focused sound waves (shock wave therapy) reduce muscle tightness in the arm after a stroke. Twelve adults who had a stroke at least six months ago received the treatment. Researchers measured changes in muscle stiffness, nerve signals, and arm funct…

This study tests whether a tool called PREP2 can help doctors better predict how well stroke patients will recover arm and leg function. The tool combines simple strength tests and brain measurements in the first days after a stroke. Researchers hope that using these predictions …

This completed study looked at 140 stroke survivors to see how many returned to driving after a formal driving assessment. Researchers reviewed medical records and conducted phone surveys to identify factors like age, gender, and stroke type that influence driving recovery. The g…

This study followed 364 adults with severe stroke who needed a breathing machine in the ICU. Researchers measured their recovery and disability levels at 3 months and 1 year after ICU admission. The goal was to better understand what happens to these patients over time, not to te…

This study looked at how often people have vision problems after a stroke. Researchers followed 127 stroke patients for 3 months, testing their eyesight and comparing results with brain scans. The goal was to find out how common these issues are and whether a simple vision screen…

This completed study looked at how often thinking, memory, and behavior problems happen after a stroke. Researchers tested over 1600 people, including stroke patients and healthy volunteers, using a French version of a standard cognitive battery. The goal was to better understand…

This completed study looked at 11,000 COVID-19 patients to understand how often they develop dangerous blood clots in arteries or veins. Researchers tracked clot rates, risk factors, and outcomes over 30 and 90 days. The goal was to learn more about these complications to improve…

This completed study looked at 258 people with different types of cardiomyopathy (a disease of the heart muscle) to see if special imaging could predict stroke risk. Researchers used echocardiograms and MRI scans to measure blood flow in the heart and check for silent brain infar…

This study tested whether robotic training that adjusts errors based on each person's abilities can improve motor learning in healthy adults and people with neurological conditions like stroke. Over 250 participants performed arm tasks with robotic devices while researchers measu…