Heart drug could shield brain after bleeding stroke

NCT ID NCT05664191

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This phase 2 trial tests whether levosimendan, a heart medication that widens blood vessels, can reduce dangerous artery spasms and delayed brain injury after a type of bleeding stroke called aneurysmal subarachnoid hemorrhage. Thirty adults in intensive care will receive either levosimendan or a placebo on day 1 and day 8. The study tracks complications like death, vasospasm, and delayed brain ischemia over 14 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Levosimendan

What this could lead to

If it works, this could point toward a treatment to prevent brain damage after a bleeding stroke.

What could go wrong

This is a very small, early pilot study with only 30 patients, so results may not be conclusive. The drug may not reduce complications or could cause side effects like low blood pressure or fast heart rate.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

acquired aneurysmal subarachnoid hemorrhage stroke disorder subarachnoid hemorrhage

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Hôpital Lariboisière, Service d'anesthésie Réanimation

    RECRUITING

    Paris, France, 75010, France

    Contact Phone: •••-•••-•••• Email: •••••@•••••