Could probiotics stop ventilator pneumonia? new trial aims to find out

NCT ID NCT06092554

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether giving probiotics (LactoLevure) to ICU patients on ventilators can prevent ventilator-associated pneumonia. The trial will enroll 186 adults with head injury, stroke, or brain hemorrhage. Patients receive probiotic or placebo capsules twice daily for 30 days. The goal is to see if probiotics reduce infection rates and deaths.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Probiotics (LactoLevure)

What this could lead to

If it works, this could provide a simple, low-cost way to prevent lung infections in ICU patients on ventilators.

What could go wrong

This is a relatively small, early-stage trial. Probiotics may not reduce infection rates, and results may not apply to all ICU patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

Brain Injuries, Traumatic intracerebral hemorrhage Pneumonia, Ventilator-Associated stroke disorder traumatic brain injury

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • AUSL Bologna Ospedale Bellaria

    RECRUITING

    Parma, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

  • Azienda Ospedaliera di Perugia

    RECRUITING

    Perugia, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Azienda Ospedaliero Universitaria di Alessandria SS. Antonio e Biagio e Cesare Arrigo

    RECRUITING

    Alessandria, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Azienda Ospedaliero Universitaria di Parma

    RECRUITING

    Parma, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

  • Azienda ospedaliera Santa Maria di Terni

    RECRUITING

    Terni, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

  • Hospital Erasme

    RECRUITING

    Brussels, Belgium

    Contact

    Contact

    Contact Email: •••••@•••••

  • Intensive Care Unit, Policlinico di Bari

    RECRUITING

    Bari, BA, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact

    Contact

    Contact

    Contact

    Contact

  • Ospedale Di Venere

    RECRUITING

    Bari, 70131, Italy

    Contact

    Contact

    Contact

    Contact Email: •••••@•••••

  • Regional General Hospital F. Miulli

    RECRUITING

    Acquaviva delle Fonti, BA, Italy

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

    Contact