Ear stimulation may guide tailored stroke recovery

NCT ID NCT06335199

Completed Knowledge-focused Sponsor: Georgia Institute of Technology Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at how stimulating a nerve in the ear (tVNS) affects pupil size in stroke survivors and healthy adults. Researchers compared stimulation on one side versus both sides to see which causes a bigger pupil response. The goal is to use pupil changes as a guide for personalizing stroke rehabilitation. The study involved 21 participants and measured pupil size during stimulation.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcutaneous vagus nerve stimulation (tVNS)
What this could lead to: If successful, this could help personalize stroke rehabilitation by identifying which stimulation method works best for each patient.
What could go wrong: This is a small, early-stage study with only 21 participants, focused on measuring pupil response rather than clinical outcomes. Results may not translate to better recovery.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

STROKE

Contacts and locations

Locations

Human Neuromuscular Physiology Lab

Atlanta, Georgia, 30318, United States

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