Stroke treatment showdown: sedation or anesthesia?
NCT ID NCT03263117
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 260 people having emergency stroke treatment to remove a clot. Some were given sedation (awake but relaxed) and others were put under general anesthesia (completely asleep). The goal was to see which approach leads to better recovery and fewer complications after 90 days.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
sedation drugs (fentanyl, midazolam, dexmedetomidine, propofol) or general anesthesia
What this could lead to
If it works, this could show that one type of anesthesia during stroke treatment leads to better recovery and less disability.
What could go wrong
This is a completed Phase 4 trial, but results may not apply to all stroke patients or settings. The choice of sedation drugs was not strictly controlled, which could affect outcomes.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Baylor College of Medicine
Houston, Texas, 77030, United States
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Geisinger Health
Danville, Pennsylvania, 17822, United States
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Henry Ford Health System
Louisville, Kentucky, 48150, United States
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Indiana University College of Medicine
Indianapolis, Indiana, 46202, United States
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Memorial Hermann Hospital System - Memorial City Medical Center
Houston, Texas, 77024, United States
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Memorial Hermann Hospital System - The Woodlands Medical Center
The Woodlands, Texas, 77380, United States
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Rochester Regional Health
Rochester, New York, 14617, United States
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Temple University
Philadelphia, Pennsylvania, 19122, United States
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University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
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University of Texas Health Science Center Houston with Memorial Hermann Hospital System - The Medical Center
Houston, Texas, 77030, United States
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Wake Forest Baptist Health
Winston-Salem, North Carolina, 27157, United States