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A bedside eye scan could reveal which kind of stroke a patient has

NCT ID NCT07818408

Diagnosis Sponsor: Ankara City Hospital Bilkent Source: ClinicalTrials.gov ↗

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

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Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
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Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
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Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 14, 2026 · Last updated Sep 15, 2026 · Updated 1 time

Summary

Researchers are testing whether a bedside ultrasound of the eye can help emergency doctors tell ischemic stroke (caused by a clot) from hemorrhagic stroke (caused by bleeding). The team measures the optic nerve sheath diameter, a marker linked to pressure inside the skull, in adults who arrive at the emergency department with stroke symptoms and have already been diagnosed by CT or MRI. The goal is to find a cut-off value that reliably separates the two stroke types, which could support faster treatment decisions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
bedside ocular ultrasonography to measure optic nerve sheath diameter
What this could lead to
If it works, emergency doctors could use a quick bedside eye ultrasound to tell bleeding strokes from clot strokes before a CT or MRI, which may speed up treatment decisions.
What could go wrong
This is a small diagnostic study of 64 people at one hospital, so the findings may not hold up in larger or more varied groups. Ultrasound results can also vary between operators and may not be accurate enough to replace standard imaging.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

64 people

The number who actually took part.

Started

Apr 2021

Finished

Dec 2021

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

The study population consists of adult patients (aged 18 years and older) who presented to the adult emergency department of a tertiary training and research hospital with symptoms of acute stroke. To be included in this population, patients must have a confirmed diagnosis of cerebrovascular disease (either ischemic or hemorrhagic stroke) verified by radiological neuroimaging (CT or MRI). The population strictly excludes intubated patients and individuals with a history or imaging evidence of pre-existing conditions that could independently raise intracranial pressure or cause cerebral edema, such as intracranial masses, aneurysms, metastases, hydrocephalus, or optic neuritis.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients older than 18 years presenting to the ED with stroke. * Patients diagnosed with cerebrovascular disease (CVD) by radiological imaging (CT/MRI). Exclusion Criteria: * Patients who are intubated. Patients unwilling to participate. * History or imaging findings of mass, aneurysm, metastasis, hydrocephalus, sarcoidosis, ventriculoperitoneal shunt, or optic neuritis. * Any condition leading to cerebral edema or affecting ONSD by independently raising intracranial pressure.

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Conditions

The condition(s) this trial relates to.

hemorrhagic stroke ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cerebrovascular accident (stroke)

Contacts and locations

Locations

  • Ankara Bilkent City Hospital Emergency Medicine Department

    Ankara, Turkey (Türkiye)

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