Blood test may reveal who recovers after a stroke

NCT ID NCT06383182

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Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time

Summary

Researchers are studying blood proteins in people who have a severe ischemic stroke caused by a blocked artery in the front of the brain. All 800 participants receive endovascular treatment, a procedure that threads a catheter through blood vessels to remove the clot. The team measures protein changes in blood samples over time and compares them with how well patients recover. The goal is to find markers that could one day help doctors predict outcomes and improve care.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
endovascular treatment, a procedure that removes a blood clot from a blocked brain artery using a catheter
What this could lead to
If researchers link certain blood proteins to recovery after clot removal, doctors could one day use a simple blood test to predict who will do well and tailor treatment.
What could go wrong
This is an observational registry, so it can show patterns but cannot prove cause and effect. Blood markers that look promising in one group of patients may not hold up in others.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 800 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jul 2024

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Patients with acute anterior circulation large vessel occlusion within 24 hours of onset who will receive endovascular treatment

Ages

18 to 80 years

Sex

Anyone

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Age: 18-80 years; 2. Patients with acute anterior circulation large vessel occlusion within 24 hours of onset who will receive endovascular treatment; 3. Pre-stroke mRS: 0-1; 4. Baseline NIHSS: ≥6; 5. Signed informed consent. Exclusion Criteria: 1. The presence of contraindications to internal jugular vein cannulation; 2. Receiving intravenous thrombolysis; 3. Haemorrhagic stroke (cerebral haemorrhage or subarachnoid haemorrhage); 4. Coagulation disorders, systemic bleeding tendency, thrombocytopenia (\<100×109/L); 5. Severe cardiac, hepatic or renal insufficiency (ALT or AST elevated more than 2 times the upper limit of normal value, or serum creatinine elevated more than 1.5 times the upper limit of normal value or in need of dialysis) or other serious medical diseases; 6. Severe uncontrolled hypertension (systolic blood pressure greater than 200 mmHg or diastolic blood pressure greater than 110 mmHg); 7. Pregnant or lactating women; 8. Other conditions who are not suitable for this trial by investigator.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

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  3. A doctor treating you

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Contacts and locations

Locations

  • General Hospital of Northern Theater Command

    RECRUITING

    Shenyang, 110840, China

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