Blood test may reveal who recovers after a stroke
NCT ID NCT06383182
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers are studying blood proteins in people who have a severe ischemic stroke caused by a blocked artery in the front of the brain. All 800 participants receive endovascular treatment, a procedure that threads a catheter through blood vessels to remove the clot. The team measures protein changes in blood samples over time and compares them with how well patients recover. The goal is to find markers that could one day help doctors predict outcomes and improve care.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- endovascular treatment, a procedure that removes a blood clot from a blocked brain artery using a catheter
- What this could lead to
- If researchers link certain blood proteins to recovery after clot removal, doctors could one day use a simple blood test to predict who will do well and tailor treatment.
- What could go wrong
- This is an observational registry, so it can show patterns but cannot prove cause and effect. Blood markers that look promising in one group of patients may not hold up in others.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 800 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jul 2024
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Patients with acute anterior circulation large vessel occlusion within 24 hours of onset who will receive endovascular treatment
- Ages
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18 to 80 years
- Sex
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Anyone
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Age: 18-80 years; 2. Patients with acute anterior circulation large vessel occlusion within 24 hours of onset who will receive endovascular treatment; 3. Pre-stroke mRS: 0-1; 4. Baseline NIHSS: ≥6; 5. Signed informed consent. Exclusion Criteria: 1. The presence of contraindications to internal jugular vein cannulation; 2. Receiving intravenous thrombolysis; 3. Haemorrhagic stroke (cerebral haemorrhage or subarachnoid haemorrhage); 4. Coagulation disorders, systemic bleeding tendency, thrombocytopenia (\<100×109/L); 5. Severe cardiac, hepatic or renal insufficiency (ALT or AST elevated more than 2 times the upper limit of normal value, or serum creatinine elevated more than 1.5 times the upper limit of normal value or in need of dialysis) or other serious medical diseases; 6. Severe uncontrolled hypertension (systolic blood pressure greater than 200 mmHg or diastolic blood pressure greater than 110 mmHg); 7. Pregnant or lactating women; 8. Other conditions who are not suitable for this trial by investigator.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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General Hospital of Northern Theater Command
RECRUITINGShenyang, 110840, China
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