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New drug aims to shield brain cells during emergency stroke procedure

NCT ID NCT05585606

Completed Disease control Sponsor: Silver Creek Pharmaceuticals Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested an experimental drug called SCP776 in 120 adults having emergency surgery to remove a blood clot after a severe stroke. The goal was to see if the drug is safe and helps protect the brain from further damage. Participants received either the drug or a placebo, and researchers monitored side effects and recovery.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE (AIS)

Contacts and locations

Locations

  • Augusta University Medical Center

    Augusta, Georgia, 30912, United States

  • Banner University Medical Center /Univ of Arizona

    Tucson, Arizona, 85719, United States

  • Hartford Hospital

    Hartford, Connecticut, 06106, United States

  • HonorHealth Scottsdale Osborn Medical Center

    Scottsdale, Arizona, 85251, United States

  • Houston Methodist Neurological Institute

    Houston, Texas, 77030, United States

  • Jefferson Abington Hospital

    Abington, Pennsylvania, 19001, United States

  • Lennox Hill Hospital

    New York, New York, 10075, United States

  • Marcus Neuroscience Institute

    Boca Raton, Florida, 33486, United States

  • Medical College of Wisconsin and Froedtert Hospital

    Milwaukee, Wisconsin, 53226, United States

  • Mercy Health - St Elizabeth Youngstown Hospital

    Youngstown, Ohio, 44504, United States

  • Mercy Health - St Vincent Medical Center

    Toledo, Ohio, 43608, United States

  • Northshore University Hospital

    Manhasset, New York, 11030, United States

  • Oregon Stroke Center at OHSU

    Portland, Oregon, 97239, United States

  • Penn State Health - M.S. Hershey Medical Center

    Hershey, Pennsylvania, 17033, United States

  • Providence Portland Medical Center

    Portland, Oregon, 97213, United States

  • Providence St. Vincent Medical Center

    West Haven-Sylvan, Oregon, 97225, United States

  • SSM Health DePaul Hospital

    Bridgeton, Missouri, 63044, United States

  • St. Luke's Hospital of Kansas City

    Kansas City, Missouri, 64111, United States

  • The Ohio State University

    Columbus, Ohio, 43210, United States

  • UNM Hospital

    Albuquerque, New Mexico, 87106, United States

  • University of Cincinnati

    Cincinnati, Ohio, 45219, United States

  • University of Miami - Jackson Memorial Hospital

    Miami, Florida, 33136, United States

More trials for these conditions

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