Could a single shot boost stroke recovery? new trial aims to find out

NCT ID NCT07466251

Not yet recruiting Disease control Sponsor: Peking Union Medical College Hospital Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jul 16, 2026 · Updated 4 times

Summary

This study tests whether a single injection of Recaticimab, a cholesterol-lowering drug, can help people recover better after a stroke caused by narrowed brain arteries. About 1,200 participants will receive either the drug or a placebo, plus standard care. The main goal is to see if more people achieve a good functional outcome (able to look after themselves) at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Recaticimab (a PCSK9 inhibitor, a type of cholesterol-lowering drug)
What this could lead to: If it works, this could provide a new treatment option to improve recovery after a stroke caused by plaque buildup in brain arteries.
What could go wrong: This is a phase 4 trial, but it hasn't started yet. The drug may not improve outcomes more than standard therapy, and there are always risks with any medication.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

intracranial arteriosclerosis ischemic stroke Plaque, Atherosclerotic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ACUTE ISCHEMIC STROKE (AIS) ATHEROSCLEROTIC PLAQUE INTRACRANIAL ATHEROSCLEROSIS ICAS

Contacts and locations

Locations

Affiliated Taihe Hospital of Hubei University of Medicine

Shiyan, Hubei, China
Baotou Central Hospital

Baotou, Inner Mongolia, 014000, China
Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

Cangzhou, Hebei, China
Chinese PLA General Hospital

Beijing, Beijing Municipality, 100853, China
Chongqing General Hospital

Chongqing, China
First Affiliated Hospital of Harbin Medical University

Harbin, Heilongjiang, China
Hebei Provincial People's Hospital

Shijiazhuang, Hebei, 050051, China
Huashan Hospital, Fudan University

Shanghai, China
Jining First People's Hospital

Jining, Shandong, 272000, China
Liaocheng People's Hospital

Liaocheng, Shandong, 252000, China
Nanjing First Hospital

Nanjing, Jiangsu, 210000, China
Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing 100730

Beijing, China
Peking University Third Hospital Qinhuangdao Hospital

Qinhuangdao, Hebei, China
Tangshan Worker's Hospital

Tangshan, Hebei, 063000, China
The Affiliated Hospital of Qingdao University

Qingdao, Shandong, China
The Third Affiliated Hospital of Sun Yat-sen University, Yuedong Hospital

Meizhou, Guangdong, China
The first affiliated hospital of zhengzhou university

Zhengzhou, Henan, China
Weifang People's Hospital

Weifang, Shandong, 261000, China
Zhongnan Hospital of Wuhan University

Wuhan, Hubei, China

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