Could a single shot boost stroke recovery? new trial aims to find out

NCT ID NCT07466251

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 2 times

Summary

This study tests whether a single injection of Recaticimab, a cholesterol-lowering drug, can help people recover better after a stroke caused by narrowed brain arteries. About 1,200 participants will receive either the drug or a placebo, plus standard care. The main goal is to see if more people achieve a good functional outcome (able to look after themselves) at 90 days.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Recaticimab (a PCSK9 inhibitor, a type of cholesterol-lowering drug)

What this could lead to

If it works, this could provide a new treatment option to improve recovery after a stroke caused by plaque buildup in brain arteries.

What could go wrong

This is a phase 4 trial, but it hasn't started yet. The drug may not improve outcomes more than standard therapy, and there are always risks with any medication.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

intracranial arteriosclerosis ischemic stroke Plaque, Atherosclerotic

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Affiliated Taihe Hospital of Hubei University of Medicine

    Shiyan, Hubei, China

  • Baotou Central Hospital

    Baotou, Inner Mongolia, 014000, China

  • Cangzhou Hospital of Integrated Traditional Chinese and Western Medicine

    Cangzhou, Hebei, China

  • Chinese PLA General Hospital

    Beijing, Beijing Municipality, 100853, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Chongqing General Hospital

    Chongqing, China

  • First Affiliated Hospital of Harbin Medical University

    Harbin, Heilongjiang, China

  • Hebei Provincial People's Hospital

    Shijiazhuang, Hebei, 050051, China

  • Huashan Hospital, Fudan University

    Shanghai, China

  • Jining First People's Hospital

    Jining, Shandong, 272000, China

  • Liaocheng People's Hospital

    Liaocheng, Shandong, 252000, China

  • Nanjing First Hospital

    Nanjing, Jiangsu, 210000, China

  • Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, Beijing 100730

    Beijing, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Peking University Third Hospital Qinhuangdao Hospital

    Qinhuangdao, Hebei, China

  • Tangshan Worker's Hospital

    Tangshan, Hebei, 063000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • The Affiliated Hospital of Qingdao University

    Qingdao, Shandong, China

  • The Third Affiliated Hospital of Sun Yat-sen University, Yuedong Hospital

    Meizhou, Guangdong, China

  • The first affiliated hospital of zhengzhou university

    Zhengzhou, Henan, China

  • Weifang People's Hospital

    Weifang, Shandong, 261000, China

  • Zhongnan Hospital of Wuhan University

    Wuhan, Hubei, China