New device aims to pull clots from the brain in major strokes

NCT ID NCT06249776

Completed Disease control Sponsor: Gravity Medical Technology, INC Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often blood flow was successfully restored and checked for serious side effects like bleeding in the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Supernova stent retriever device (mechanical thrombectomy)
What this could lead to: If successful, this device could offer a new option to quickly remove blood clots and restore blood flow in people having a severe stroke.
What could go wrong: This was a small, early study with only 55 participants. The device may not work better than existing treatments, and there are risks like bleeding in the brain or death.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

brain disorder brain infarction brain ischemia cardiovascular disorder central nervous system disorder cerebrovascular disorder ischemic stroke large artery stroke nervous system disorder stroke disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

BRAIN DISEASES CARDIOVASCULAR DISEASES CENTRAL NERVOUS SYSTEM DISEASES CEREBROVASCULAR DISORDERS ISCHEMIC STROKE NERVOUS SYSTEM DISEASES STROKE VASCULAR DISEASES

Contacts and locations

Locations

All India Institute of Medical Sciences, New Delhi

New Delhi, National Capital Territory of Delhi, 110029, India
Apollo Hospitals

Hyderabad, Telangana, 500096, India
Dr Balabhai Nanavati Hospital

Mumbai, Maharashtra, 400056, India
Jawaharlal Institute of Postgraduate Medical Education and Research

Puducherry, Puducherry, 605006, India
Marengo CIMS Hospital

Ahmedabad, Gujarat, 380060, India
National Institute of Cardiovascular Diseases

Karachi, Sindh, 75510, Pakistan
P.D. Hinduja Hospital and Medical Research Centre

Mumbai, Maharashtra, 400016, India
Tehran University of Medical Sciences

Tehran, Tehran Province, 1416753955, Iran
The Calcutta Medical Research Institute

Kolkata, West Bengal, 700027, India
Yashoda Hospitals, Secunderabad

Hyderabad, Telangana, 500082, India
Yashoda Hospitals, Somajiguda

Hyderabad, Telangana, 500082, India

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