New device aims to pull clots from the brain in major strokes

NCT ID NCT06249776

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested a new device called the Supernova stent retriever in 55 people with severe stroke caused by a large blood clot in the brain. The device is threaded through blood vessels to grab and remove the clot, restoring blood flow. Researchers measured how often blood flow was successfully restored and checked for serious side effects like bleeding in the brain.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Supernova stent retriever device (mechanical thrombectomy)

What this could lead to

If successful, this device could offer a new option to quickly remove blood clots and restore blood flow in people having a severe stroke.

What could go wrong

This was a small, early study with only 55 participants. The device may not work better than existing treatments, and there are risks like bleeding in the brain or death.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for CARDIOVASCULAR DISEASES are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

brain disorder brain infarction brain ischemia cardiovascular disorder central nervous system disorder cerebrovascular disorder ischemic stroke large artery stroke nervous system disorder stroke disorder vascular disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • All India Institute of Medical Sciences, New Delhi

    New Delhi, National Capital Territory of Delhi, 110029, India

  • Apollo Hospitals

    Hyderabad, Telangana, 500096, India

  • Dr Balabhai Nanavati Hospital

    Mumbai, Maharashtra, 400056, India

  • Jawaharlal Institute of Postgraduate Medical Education and Research

    Puducherry, Puducherry, 605006, India

  • Marengo CIMS Hospital

    Ahmedabad, Gujarat, 380060, India

  • National Institute of Cardiovascular Diseases

    Karachi, Sindh, 75510, Pakistan

  • P.D. Hinduja Hospital and Medical Research Centre

    Mumbai, Maharashtra, 400016, India

  • Tehran University of Medical Sciences

    Tehran, Tehran Province, 1416753955, Iran

  • The Calcutta Medical Research Institute

    Kolkata, West Bengal, 700027, India

  • Yashoda Hospitals, Secunderabad

    Hyderabad, Telangana, 500082, India

  • Yashoda Hospitals, Somajiguda

    Hyderabad, Telangana, 500082, India