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Shockwave and cold combo may ease stroke shoulder pain

NCT ID NCT07196267

Symptom relief Sponsor: MTI University Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested whether combining two physical therapies—extracorporeal shockwave therapy and cryoflow (cold) therapy—can reduce shoulder pain and spasticity in stroke survivors with rotator cuff tendonitis. Thirty participants received either one therapy alone or both together over 8 weeks. Researchers measured pain, range of motion, and muscle tone to see which approach works best.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Extracorporeal Shockwave Therapy and Cryoflow Therapy
What this could lead to
If it works, this could offer a non-drug way to reduce shoulder pain and spasticity, helping stroke survivors move better and regain arm function.
What could go wrong
This is a small, early study with only 30 participants, so results may not apply to everyone. The therapies may not work better than existing treatments.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

30 people

The number who actually took part.

Started

Oct 2025

Finished

Nov 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

50 to 70 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Diagnosis of stroke confirmed by neurologist via physical examination and MRI. Age between 50 and 70 years. Moderate to severe shoulder spasticity, graded as Stage 3 on the Modified Ashworth Scale (MAS) for shoulder adductors. Medically stable (vital signs within normal limits). Conscious, cooperative, and able to follow instructions. No orthopedic conditions, surgeries, or injuries affecting the shoulder or upper limb. No sensory impairments (visual, auditory, proprioceptive) that would interfere with assessment or treatment. Able to provide informed consent. Exclusion Criteria: * History of shoulder surgery or fracture. Presence of shoulder subluxation or dislocation. Severe cognitive impairment or inability to communicate. Uncontrolled hypertension, cardiac disease, or other unstable medical conditions. Skin lesions, open wounds, or infection over the shoulder region. Diagnosis of frozen shoulder (adhesive capsulitis), rheumatoid arthritis, or other inflammatory joint diseases. Previous treatment with ESWT or cryotherapy for shoulder within the last 6 months. Use of botulinum toxin injections in the upper limb within the last 3 months

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Conditions

The condition(s) this trial relates to.

rotator cuff syndrome stroke disorder tendinitis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Post-stroke shoulder pain,rotator cuff tendonitis,shoulder spasticity

Contacts and locations

Locations

  • Faculty of Physical Therapy, Benha University

    Cairo, Egypt

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