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Head elevation after stroke: simple move, big impact?

NCT ID NCT06115707

Disease control Sponsor: Zhengzhou Yuan Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether raising the head after a stroke procedure helps patients recover better. Over 1,300 adults with severe strokes were followed for 90 days to see if head elevation improved their ability to function. The goal was to find a simple, low-cost way to boost recovery after emergency treatment.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

1,368 people

The number who actually took part.

Started

Nov 2023

Finished

Apr 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Clinical signs consistent with acute ischemic stroke; 2. Age ≥ 18 years old; 3. Proved anterior circulation large vessel occlusion on digital subtraction angiography (ICA, M1, M2) with/without cervical lesion (tandem); 4. NIHSS score ≥ 8 points before endovascular treatment; 5. ASPECTS score ≤ 7 points before endovascular treatment; 6. Successful vessel recanalization after endovascular treatment (defined as an eTICI score of 2b, 2c, or 3) ； 7. The time from onset to randomization ≤ 24 hours (the onset time is defined as the last normal time); 8. Written informed consent is obtained from patients and/or their legal representatives. Exclusion Criteria: 1. Pre-stroke mRS score\>1 point; 2. Patients with acute occlusions in multiple vascular territories (e.g. bilateral anterior circulation, or anterior/posterior circulation); 3. Currently in pregnant or lactating or serum beta HCG test is positive on admission; 4. Contraindications to a flat head position; 5. Any terminal illness with life expectancy less than 6 months; 6. Participating in other clinical trials; 7. Patients with a preexisting neurological or psychiatric disease that would confound the neurological functional evaluations; 8. Unlikely to be available for 90-day follow-up.

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Conditions

The condition(s) this trial relates to.

cerebral artery occlusion large artery stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Endovascular therapy Stroke, acute

Contacts and locations

Locations

  • Affiliated Hospital of North Sichuan Medical College

    Nanchong, Sichuan, China

  • Affiliated Hospital of Southwest Medical University

    Luzhou, Sichuan, 646000, China

  • Anyang People's Hospital

    Anyang, Henan, China

  • Baise People's Hospital

    Baise City, Guangxi, China

  • Baoji High tech Hospital

    Baoji, Shaanxi, China

  • Beichuan County People's Hospital

    Mianyang, Sichuan, China

  • Chengdu Sixth People's Hospital

    Chengdu, Sichuan, China

  • Chongqing Banan District People's Hospital

    Chongqing, Chongqing Municipality, China

  • Chongqing Bishan District People's Hospital

    Chongqing, Chongqing Municipality, China

  • Chongqing Ninth People's Hospital

    Chongqing, Chongqing Municipality, China

  • Chongzhou People's Hospital

    Chengdu, Sichuan, China

  • Dalian 967 Hospital

    Dalian, Liaoning, China

  • Deyang People's Hospital

    Deyang, Sichuan, China

  • Dingxi People's Hospital

    Dingxi, Gansu, China

  • Fushun County People's Hospital

    Zigong, Sichuan, China

  • Gansu Provincial Hospital of Traditional Chinese Medicine

    Lanzhou, Gansu, China

  • Ganzhou Municipal Hospital

    Ganzhou, Jiangxi, China

  • Ganzhou People's Hospital

    Ganzhou, Jiangxi, China

  • Guangdong Provincial People's Hospital Heyuan Hospital

    Heyuan, Guangdong, China

  • Guangyuan First People's Hospital

    Guangyuan, Sichuan, China

  • Gulin County People's Hospital

    Luzhou, Sichuan, China

  • Jiamusi Central Hospital

    Jiamusi, Heilongjiang, China

  • Jiangxi Provincial People's Hospital

    Nanchang, Jiangxi, China

  • Jiuquan People's Hospital

    Jiuquan, Gansu, China

  • Lanzhou University First Hospital

    Lanzhou, Gansu, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, China

  • Liangshan First People's Hospital

    Xichang, Sichuan, China

  • Longyan First Hospital

    Longyan, Fujian, 364099, China

  • Mianyang 404 Hospital

    Mianyang, Sichuan, China

  • Mianyang Central Hospital

    Mianyang, Sichuan, China

  • Nanning Third People's Hospital

    Nanning, Guangxi, China

  • Neijiang Second People's Hospital

    Neijiang, Sichuan, China

  • Ningxia Hui Autonomous Region People's Hospital

    Yinchuan, Ningxia, China

  • Ningxiang First People's Hospital

    Changsha, Hunan, China

  • Northwest University Affiliated Hospital

    Xi'an, Shaanxi, China

  • Qiannan Prefecture People's Hospital

    Duyun, Guizhou, China

  • Qujing First People's Hospital

    Qujing, Yunnan, China

  • Rizhao Traditional Chinese Medicine Hospital

    Rizhao, Shandong, China

  • Shanxi Provincial Hospital

    Taiyuan, Shanxi, China

  • Shiyan taihe hospital

    Shiyan, Hubei, China

  • Suining Central Hospital

    Suining, Sichuan, China

  • Suining First People's Hospital

    Suining, Sichuan, China

  • The Fifth People's Hospital of Qinghai Province

    Xining, Qinghai, China

  • The First Affiliated Hospital of Fujian Medical University

    Fuzhou, Fujian, China

  • The First Affiliated Hospital of Hainan Medical College

    Haikou, Hainan, China

  • The First Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, China

  • The First Hospital of Jilin University

    Changchun, Jilin, China

  • The First People's Hospital of Chenzhou City

    Chenzhou, Hunan, China

  • The Second Affiliated Hospital of Kunming Medical University

    Kunming, Yunnan, China

  • The Seventh Affiliated Hospital of Xinjiang Medical University

    Ürümqi, Xinjiang, China

  • Tianshui First People's Hospital

    Tianshui, Gansu, China

  • Wenzhou Medical University First Affiliated Hospital

    Wenzhou, Zhejiang, China

  • Xianyang First People's Hospital

    Xianyang, Shaanxi, China

  • Xichang People's Hospital

    Xichang, Sichuan, China

  • Xidian Group Hospital

    Xi'an, Shaanxi, China

  • Xihua County People's Hospital

    Zhoukou, Henan, China

  • Xingguo County People's Hospital

    Ganzhou, Jiangxi, China

  • Xingyi People's Hospital

    Xingyi, Guizhou, China

  • Ya'an People's Hospital

    Ya'an, Sichuan, China

  • Yibin Second People's Hospital

    Yibin, Sichuan, China

  • Yichun First Hospital

    Yichun, Heilongjiang, China

  • Yongchuan Hospital Affiliated to Chongqing Medical University

    Chongqing, Chongqing Municipality, China

  • Yulin First Hospital

    Yulin, Shaanxi, China

  • Zhujiang Hospital of Southern Medical University

    Guanzhou, Guangdong, China

  • Zigong First People's Hospital

    Zigong, Sichuan, China

  • Zigong Fourth People's Hospital

    Zigong, Sichuan, China

  • Zigong Third People's Hospital

    Zigong, Sichuan, China

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