Can a Mega-Dose of statin help stroke patients? new safety trial says maybe

NCT ID NCT01976936

Completed Symptom relief Sponsor: Columbia University Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested whether giving a very high dose of lovastatin (a common cholesterol drug) for 3 days after a stroke is safe. 162 stroke patients received either the high-dose drug or a placebo within 24 hours of symptoms. The main goal was to check for liver or muscle damage, with follow-up for 3 months.

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Conditions

The condition(s) this trial relates to.

ischemic stroke Jaundice Rhabdomyolysis stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

JAUNDICE RHABDOMYOLYSIS STROKE

Contacts and locations

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Locations

Brigham & Women's Hospital

Boston, Massachusetts, 02115, United States
Emory University

Atlanta, Georgia, 30322, United States
Jackson Memorial Hospital

Miami, Florida, 33136, United States
Mount Sinai School of Medicine

New York, New York, 10029, United States
The Hospital of the University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States
University of California, Los Angeles Stroke Network

Los Angeles, California, 90024, United States
University of Miami Miller School of Medicine

Miami, Florida, 33136, United States

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