Can walking while thinking rewire the Stroke-Damaged brain?
NCT ID NCT06129227
First seen Sep 17, 2026 · Last updated Sep 18, 2026 · Updated 1 time
Summary
Researchers are testing whether a dual-task exercise program helps stroke survivors walk while doing a mental task. The study compares dual-task training, which combines walking with cognitive activities, to single-task training, where walking and thinking are practiced separately. They use functional near-infrared spectroscopy to measure brain activity during dual-task walking. The trial enrolls 108 adults who are at least six months past their stroke and can walk for one minute on their own.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Dual-task exercise training, which combines walking practice with mental tasks
- What this could lead to
- If dual-task training helps, it could offer stroke survivors a way to improve walking while doing everyday mental tasks, such as talking or remembering where they are going.
- What could go wrong
- This is a small, early study. Dual-task training may not improve walking or thinking more than single-task training, and brain imaging results may be hard to interpret.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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108 people
The number who actually took part.
- Started
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Nov 2023
- Finished
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Jun 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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50 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Diagnosis of stroke confirmed by brain scan reports * Community-living * Stroke onset ≥ 6 months * Aged 50 years or older * Modified Rankin scale 1-3 * Capable of following verbal instructions * Montreal Cognitive Assessment score ≥ 22 * Ability to walk for 1 min independently with or without a walking aid * Not receiving formal rehabilitation elsewhere Exclusion Criteria: * Other neurological disorders * Pain or other comorbidities that seriously affect the ability to walk * Contraindications to exercise (e.g., angina).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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The Hong Kong Polytechnic University
Hong Kong, Hong Kong, 000000, Hong Kong
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