Can intensive hand therapy help babies recover from stroke?
NCT ID NCT03910075
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a new intensive therapy called I-ACQUIRE for infants aged 8 to 36 months who had a stroke around birth and have weakness on one side. The therapy involves guided play and movement exercises for either 3 or 6 hours a day, 5 days a week for 4 weeks. Researchers compared these two dosages to standard rehab to see if the therapy helps babies gain new arm and hand skills.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
I-ACQUIRE therapy (a form of pediatric constraint-induced movement therapy)
What this could lead to
If successful, this could establish an effective rehabilitation approach to improve arm and hand function in infants who had a stroke around birth.
What could go wrong
The trial is completed but results are not yet widely reported. The therapy is intensive (up to 6 hours daily) and may be difficult for families to sustain. Benefits may vary by child.
Disclaimer
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the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Ann & Robert H. Lurie Children's Hospital of Chicago
Chicago, Illinois, 60611, United States
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Boston Children's Hospital
Boston, Massachusetts, 02115, United States
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C.S. Mott Children's Hospital
Ann Arbor, Michigan, 48109, United States
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Children's Hospital of Philadelphia
Philadelphia, Pennsylvania, 19104, United States
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Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio, 45229, United States
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Fralin Biomedical Research Institute at Virginia Tech
Roanoke, Virginia, 24016, United States
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Kennedy Krieger Institute - Fairmount Rehabilitation
Baltimore, Maryland, 21231, United States
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Martha Morehouse Medical Plaza
Columbus, Ohio, 43210, United States
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Memorial Hermann Texas Medical Center
Houston, Texas, 77030, United States
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Scottish Rite for Children - Dallas
Dallas, Texas, 75219, United States
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The Medical University of South Carolina (MUSC)
Charleston, South Carolina, 29425, United States
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USCD Health La Jolla
La Jolla, California, 92037, United States
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University of Wisconsin School of Medicine and Public Health
Madison, Wisconsin, 53792, United States
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Washington University School of Medicine, St. Louis Children's Hospital
St Louis, Missouri, 63110, United States
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Yale New Haven Children's Hospital
New Haven, Connecticut, 06511, United States