Massive study tests everyday supplements against autoimmune disease and aching knees

NCT ID NCT01351805

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This large study looked at whether taking daily vitamin D or fish oil supplements could lower the risk of developing autoimmune diseases (like rheumatoid arthritis), reduce signs of inflammation in the blood, and ease chronic knee pain. Over 25,000 adults without prior cancer or heart disease took part. Researchers measured inflammation markers and tracked new autoimmune cases and knee pain severity over time.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Brigham and Women's Hospital

    Boston, Massachusetts, 02115, United States

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