Could a Two-Pill combo cut stroke recurrence?

NCT ID NCT06638151

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

After a stroke, patients are at high risk of having another one, especially in the first 21 days. This study tests whether adding clopidogrel to the standard aspirin treatment is safe and feasible for preventing a second stroke. About 200 patients who had a mild to moderate stroke will be randomly assigned to take either aspirin alone or aspirin plus clopidogrel for 21 days, then followed for three months.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

aspirin and clopidogrel (antiplatelet medications)

What this could lead to

If successful, this could show that a short course of dual antiplatelet therapy is a safe and effective way to reduce the risk of a second stroke in the first three weeks after treatment.

What could go wrong

This is a small, early-phase pilot study, so results may not be conclusive. The main risk is bleeding, and the study only includes patients with mild to moderate strokes, so findings may not apply to everyone.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

ischemic stroke stroke disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University of Alberta Hospital

    RECRUITING

    Edmonton, Alberta, T6G2B7, Canada

    Contact Phone: •••-•••-•••• Email: •••••@•••••