Experimental stroke drug PP-007 passes early safety check in 24 patients

NCT ID NCT04677777

First seen Nov 16, 2025 · Last updated May 16, 2026 · Updated 22 times

Summary

This early-stage study tested the safety of an experimental drug called PP-007 in 24 people having an acute ischemic stroke (a stroke caused by a blood clot). Participants received two doses of the drug along with standard treatments like clot-busting medicine or clot removal. The study monitored vital signs, bleeding risks, and other side effects to see if the drug is safe enough for further testing.

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Contacts and locations

Locations

  • Baptist Health Miami Cardiac & Vascular Institute (MCVI)

    Miami, Florida, 33176, United States

  • Baptist Health Research Institute

    Jacksonville, Florida, 32207, United States

  • Emory University School of Medicine

    Atlanta, Georgia, 30303, United States

  • Mercy Health - St. Vincent Medical Center

    Toledo, Ohio, 43608, United States

  • Oregon Stroke Center at Oregon Health & Science University (OHSU)

    Portland, Oregon, 97239, United States

  • Saint Luke's Hospital

    Kansas City, Missouri, 64111, United States

  • UPMC Stroke Institute

    Pittsburgh, Pennsylvania, 15213, United States

  • University of Oklahoma Health Sciences Center

    Oklahoma City, Oklahoma, 73104, United States

Conditions

Explore the condition pages connected to this study.