Specific developmental disorder

This phase 3 trial tests whether a new formulation of dexmethylphenidate (CTx-1301) can improve attention and reduce ADHD symptoms in adults for up to 16 hours. Participants take an optimized dose (25, 37.5, or 50 mg) and complete math tests in a simulated classroom. The study co…

This study tests an oral capsule called AK0901 (AZSTARYS) in children aged 6 to 12 with attention deficit hyperactivity disorder (ADHD). The trial compares the drug against a placebo to see if it reduces ADHD symptoms like inattention and hyperactivity. Researchers measure sympto…

This Phase 3 study tested whether ecopipam can safely maintain tic control in 216 people with Tourette's disorder, ages 6 and up. Participants first received open-label ecopipam, then those who responded were randomly switched to placebo or continued ecopipam to see if benefits l…

This completed trial in Xishui, China, tested a community-based program for 3,571 adults aged 35 and older who were at high risk for COPD and had mental health symptoms. The program included lung function tests, digital mental health support, smoking cessation help, and health ed…

This study tested whether N-acetylcysteine (NAC), an antioxidant drug, can improve motor skills and learning in children with neurofibromatosis type 1 (NF1). Twenty-five children aged 8 to 16 took NAC or a placebo for 8 weeks. The goal was to see if NAC is safe and helps with mov…

This study tested a noninvasive brain stimulation technique (transcranial random noise stimulation) to see if it could reduce cravings in 225 adults with substance use disorder plus another psychiatric condition like ADHD, bipolar disorder, or schizophrenia. The approach targeted…

This study tested the long-term safety of a daily medication called centanafadine in 680 children and teens (ages 4-17) with ADHD. The drug is a non-stimulant capsule taken once a day. Researchers tracked side effects over time to see if it is safe for extended use. The trial is …

This study tested three ways to help children aged 7-11 with ADHD: a computer-based cognitive training program using a virtual classroom, the medication methylphenidate, and supportive talk therapy. Fifty-one children took part to see which approach best improves attention and re…

This study tested a Norwegian intensive habilitation program for children aged 2-6 with severe cerebral palsy or similar brain damage. The program aimed to improve the child's daily living skills and empower parents. 93 children and their families took part in a randomized trial …

This Phase 3 trial tested a once-daily extended-release capsule called centanafadine in 315 adults with both ADHD and anxiety (generalized or social anxiety). For 8 weeks, participants received either the drug or a placebo. The study measured changes in ADHD symptoms using a clin…

This study tested whether tolcapone, a drug used for Parkinson's disease, could change how people with both alcohol use disorder and ADHD respond to alcohol and make decisions. 23 adults completed the trial, which involved taking tolcapone or a placebo and then undergoing alcohol…

This completed study in Damietta, Egypt, involved 300 children aged 3 to 5 years to find out how common developmental delays are and whether early physical therapy can help. Kids with delays received twice-weekly therapy for six months, focusing on motor, language, and social ski…

This study tested the drug Qelbree (viloxazine) in 161 adults with ADHD who also had mood symptoms. Participants took the medication for several weeks, and researchers tracked changes in ADHD symptoms using a standard rating scale. The goal was to see if Qelbree is both safe and …

This study tested a summer program called Summer Academy for 124 young children with behavior problems who were about to start kindergarten. The program aimed to improve their school readiness and behavior. Researchers measured progress right after the program and again six month…

This study tested whether repeated low doses of LSD (called MM120) can safely help adults with ADHD. Fifty-three adults took either the drug or a placebo, and researchers measured changes in ADHD symptoms using a standard rating scale. The goal was to see if this approach could b…

This study tested two online versions of parent management training for children diagnosed with conduct disorder or oppositional defiant disorder. Researchers wanted to see if online delivery could help families who cannot access in-person therapy. The study involved 86 children …

This study tested whether an in-vehicle device that gives real-time feedback on driving, plus optional parent communication training, can reduce risky driving and traffic violations among teens who recently got a moving violation. 240 teens aged 16-17 with a valid Ohio license an…

This study tested whether a personalized treatment plan—based on each person's test results—works better than standard care for people with mild cognitive impairment or early-stage dementia. 73 adults aged 45-76 took part, receiving either the tailored plan or usual care for 9 mo…

This completed study tested a digital app called Poppins Clinical in 306 children with dyslexia or other reading/writing learning disabilities. The app combines musical and cognitive exercises with reading training. One group used the app plus bi-monthly speech therapy, while the…

This pilot trial tested whether taking oral zinc every day for 6 months is safe and doable for people with GNAO1 disorders, a rare genetic condition that causes movement problems, seizures, and developmental delays. 13 participants aged 6 months to 30 years took zinc acetate. The…

This study looked at whether a brain-computer interface (BCI)-based attention training program, used alone or with medications like methylphenidate or citicoline, can improve attention and executive function in school-age children with ADHD. 174 children participated in this real…

This study tested a phone-based program called MommyCheckup to see if it helps pregnant women who drink alcohol cut back or stop. The program includes a short motivational video and tailored text messages. Researchers enrolled 384 pregnant women across three states to see if the …

This early-stage study tested a drug called NFC-1 in 30 adolescents aged 12-17 with ADHD who also have specific genetic changes affecting brain receptors. The goal was to check the drug's safety and how the body processes it, while also looking for signs it might reduce ADHD symp…

This study tested whether a team-based care model can help people with both opioid use disorder and mental health issues like depression or anxiety. 254 adults in primary care received either full collaborative care for both conditions or just mental health support. The goal was …

This completed study tested whether a special diet plus a nutritional supplement called T-2 could improve thinking skills, sleep, and overall health in 76 people with Down syndrome, autism, or ADHD, aged 2 to 35. Participants followed either the diet alone, the diet plus suppleme…

This completed study tested whether a Mediterranean diet could improve metabolic syndrome markers in 30 hospitalized adults with psychiatric conditions. Participants followed either a Mediterranean diet or a standard hospital diet for 8 weeks, then switched. Researchers measured …

This study tested a virtual reality application to help diagnose Attention Deficit Hyperactivity Disorder (ADHD) in children aged 8 to 12. The goal was to see if a 3D immersive environment could better measure attention and behavior compared to standard tests. Thirty children wit…

This completed study collected speech samples from 931 children aged 2 to 14 to test a new diagnostic app called 'Hi Dongdong'. The app uses AI to assess articulation and pronunciation, comparing it to a standard test. The goal was to see if the app can accurately identify speech…

This study tested a device called EarliPoint that tracks where children look while watching short videos. The goal was to see if it could help diagnose autism spectrum disorder (ASD) in children ages 2.5 to 7. Nearly 1,000 children participated, and the device's results were comp…

This study is developing and testing a smartphone app designed for Native American women to help them avoid pregnancy affected by alcohol. Researchers will gather feedback and pilot test new features with 407 women who are at risk. The goal is to reduce risky drinking and improve…

This study tested a web-based simulation to help college students with ADHD prescriptions avoid giving away or misusing their medication. About 250 students from three universities used the program, which taught them how to say no to requests for their pills and how to talk to th…

This study tested a program called Creating Peace that helps teens aged 14-19 learn to prevent violence and address racism. Over 500 teens took part in community groups. The program aimed to reduce physical, sexual, and emotional violence, as well as weapon carrying, by teaching …

This study tested a program called Babble Boot Camp for babies with classic galactosemia, a rare condition that often causes speech and language problems. The program started when babies were 2 to 24 months old and involved weekly online coaching for parents from a speech therapi…

This study tested a culturally adapted mobile health program called Mobile CHOICES to help urban American Indian and Alaska Native young women (ages 16-20) avoid drinking alcohol during pregnancy. The goal was to reduce the risk of Fetal Alcohol Spectrum Disorders, which cause li…

This study tested whether giving teens with ADHD and their parents a question list or a short video before a doctor visit helps them talk more openly and get better care. About 126 English-speaking teens aged 11-17 with ADHD took part. The goal was to see if these tools improve s…

This study tests a non-invasive brain stimulation technique called tACS in 50 children and teens aged 6-18 with ADHD. The goal is to see if a mild electrical current applied to the scalp can improve attention and executive function. Participants will receive both real and sham st…

This trial tests whether rhythmic electrical pulses delivered to the wrist (median nerve stimulation) can reduce tics and the urge to tic in people with Tourette syndrome or chronic tic disorder. Participants wear a portable device for 15 minutes at a time over four weeks. The st…

This study tested a counseling program called Youth Friendship Bench SA for young women aged 18-25 in South Africa who had symptoms of depression, anxiety, or stress. The program included individual and group counseling sessions, plus optional text reminders. The goal was to see …

This study tests whether cognitive behavioural therapy for insomnia (CBT-I) can improve sleep and ADHD symptoms in adolescents aged 12 to 18 who have both ADHD and insomnia. Participants receive either CBT-I plus usual care or usual care alone. The goal is to see if addressing in…

This study tested a virtual reality program called Impact VR to help youth aged 10-17 with conduct disorder learn to recognize and regulate emotions. The program involved four weekly sessions in a private setting. Researchers measured changes in callous-unemotional traits, conduc…

This study tested whether Collaborative Problem Solving (CPS), a behavioral approach that teaches caregivers to address children's underlying thinking skill deficits, can improve executive function and reduce behavioral symptoms in 54 youth receiving home-based mental health care…

This study tested a structured online program for parents of children with autism or ADHD. 90 families took part to see if the program could lower parental stress, improve coping skills, and boost social support. Researchers compared parents who received the program to those who …

This study tested a personalized brain-training method called neurofeedback for children with ADHD. 51 children participated, and the training was tailored to each child's unique brain patterns. The goal was to see if this approach could improve attention and reduce ADHD symptoms…

This study tested an online training program called CHATO for nursing home staff who care for people with Alzheimer's or other dementias. The training aimed to improve how staff communicate, which may reduce behavioral symptoms like agitation or rejection of care. Over 5,000 staf…

This study tested a drug called ecopipam in 40 children aged 7 to 17 with Tourette's syndrome. The goal was to see if it could reduce the frequency and severity of their motor and vocal tics. The drug works by blocking certain dopamine receptors in the brain. The main measure was…

This pilot study tested whether adding cognitive behavioral therapy (CBT) to usual care helps reduce irritability and suicidal thoughts in children aged 8 to 12 with anger and aggression issues. 46 children were assigned to either CBT plus usual care or usual care alone. The ther…

This study tested whether a 4-week program using active video games (exergames) on the Nintendo Switch could help adults with mental illness feel better and stay motivated. Twelve participants were split into two groups: one played exergames, the other continued their usual routi…

This Phase 2 trial tested a new drug called EB-1020 SR (centanafadine) in 45 adult men with ADHD. The goal was to see if it could reduce symptoms like inattention and hyperactivity. Participants took the drug or a placebo for a few weeks, and researchers measured changes using a …

This study tested a 6-week program called BUILT for families with children aged 6 to 12 who have ADHD. The program teaches healthy habits around sleep, nutrition, and exercise to help improve focus and behavior. Researchers measured changes in physical activity, sleep, diet, and …

This study tested whether adding a virtual reality (VR) module that helps children imagine future events could improve standard brain-training exercises for kids with ADHD. Eighty children aged 5 to 12 took part, with half doing only the standard training and half also using VR h…

This study tested a new system called FamilyNet that uses a smart speaker and a mobile app to help parents of children aged 10-17 with challenging behaviors like oppositional defiant disorder or conduct disorder. The system helps parents create a positive behavior plan and sends …

This study tested whether smelling lemon essential oil for 5 minutes could improve attention in 52 children aged 9-16 with ADHD who were not on medication. The children were randomly assigned to inhale either lemon oil or a placebo before taking attention and memory tests. Result…

This study tested a program called 'My DEER Compassion' that teaches self-compassion skills to children with ADHD. 96 children in Hong Kong, along with their parents, took part in sessions to learn how to be kinder to themselves. The goal was to see if this could improve their em…

This study tested a non-invasive device that gently stimulates a nerve on the forehead (trigeminal nerve) during sleep to see if it can reduce ADHD symptoms in children ages 7 to 12. Over 200 children used either the active device or a sham (inactive) device nightly for 4 weeks. …

This study tested two non-drug therapies—graded motor imagery (mental rehearsal) and mirror therapy (using a mirror to trick the brain)—in 44 chronic stroke patients aged 45 to 65. The goal was to see which better reduces muscle spasticity and improves independence. Both therapie…

This study looked at the safety and tolerability of the drug Azstarys in 123 children aged 4 to 5 with ADHD over 12 months. Researchers monitored sleep, weight, and height changes, as well as how well the drug controlled ADHD symptoms. The goal was to see if this medication could…

This study tested whether adding a gentle brain stimulation technique called tDCS to a reading therapy (PMT) could help stroke survivors with aphasia read better. Six people with chronic aphasia took part. The goal was to see if the combination improved reading accuracy more than…

This Phase II trial tested PDC-1421, a capsule made from a plant extract, in 99 adults with ADHD. Participants were randomly assigned to receive the capsule or a placebo for up to 8 weeks. The goal was to see if the treatment could reduce ADHD symptoms and to check its safety.

This study tested a Spanish-language program called Unstuck and On Target with 20 families in Ecuador. Children aged 8-11 with autism or ADHD took part in an 8-week program to improve flexibility and problem-solving. The goal was to see if the program was practical and helpful fo…

This study tested a gentle, non-invasive brain stimulation technique called tDCS in 14 people who had a stroke at least a year ago and still have trouble finding words (aphasia). The goal was to see if stimulating a key language area could improve their ability to name pictures a…

This study tested a program called PRISM, which teaches skills like stress management and goal setting, to see if it helps racial minority patients with serious illnesses feel more resilient and communicate better with their healthcare providers. The study enrolled 28 seriously i…

This study tested whether 3 weeks of intensive language therapy (at least 2 hours daily, 5 days a week) helps people with long-term aphasia after a stroke communicate better in everyday situations. 156 participants with aphasia for at least 6 months were assigned to either immedi…

This study tested whether an adapted form of Narrative Exposure Therapy (NET) is acceptable and helpful for adults with mild learning disabilities who have experienced trauma. Thirteen participants completed the therapy, which involved talking through their life events in a struc…

This study looked at whether a structured yoga program can help children aged 7–11 with Developmental Coordination Disorder (DCD) — a condition that makes everyday tasks like tying shoes or catching a ball hard. Forty children took part to see if yoga could improve their movement…

This study tested whether a once-daily capsule called centanafadine helps reduce ADHD symptoms in children aged 4 to 12. Over 500 children took either the drug or a placebo for 6 weeks. Researchers measured changes in ADHD rating scales to see if the drug works better than a suga…

This study looked at whether a long-acting medication called guanfacine (TAK-503) can help children and teenagers aged 6 to 17 with ADHD who did not get better with standard stimulant treatments. The study had two parts: first, participants were randomly assigned to receive guanf…

This study tested whether phosphatidylserine supplements with or without DHA (an omega-3 fat) could improve thinking skills in children with ADHD. 45 children aged 10-14 who had never taken ADHD medication took either a placebo or one of three supplement formulas daily for 8 week…

This study tested the PACE technique, a therapy that encourages people with aphasia to use any form of communication—like gestures, drawing, or writing—to get their message across. Sixteen adults aged 45 to 65 with mild to moderate aphasia took part. Half received PACE plus stand…

This study tested whether a pet therapy program, based on the Human Caring Theory, could reduce stress and improve social and communication skills in children aged 7-11 with speech and language disorders. Thirty-six children participated, with some receiving six sessions of anima…

This study tested whether a brain-training technique called neurofeedback, combined with virtual reality (VR), could improve attention and self-control in children with ADHD. 138 children aged 7-12 took part in 16 training sessions over 8 weeks. The goal was to see if this approa…

This small pilot study tested whether a gentle electrical current applied to the brain (tACS) could improve naming ability in 11 people with chronic aphasia after a stroke. Participants received either real or sham stimulation during language training over two weeks. The goal was…

This study tested a six-week summer camp program to help children aged 4-6 with developmental language disorder improve their grammar. 24 children received language therapy during the camp and were tested again six weeks later to see if they kept their new skills. The goal was to…

This study tested a new type of therapy called reminder-focused positive psychiatry (RFPP) for teenagers who have both ADHD and PTSD. The goal was to see if the therapy is acceptable and helpful for reducing symptoms. Eleven teens took part, and the study measured how well they l…

This pilot study tested a 4-week laughter yoga program (8 sessions, 15 minutes each) in 45 adolescents with intellectual or physical disabilities at a special school in Hong Kong. Half did laughter yoga, half got routine care. The goal was to see if laughter yoga could improve mo…

This completed trial tested whether LEGO therapy can improve social skills in 50 adolescents aged 10–14 with high-functioning autism. Participants attended 12 weekly 90-minute group LEGO sessions over 3 months. Researchers compared their social skills to a control group who conti…

This study looked at whether creating personalized profiles for children with disruptive behavior disorders (like ADHD or oppositional defiant disorder) and their parents could help predict which therapy works best. Researchers tested two common treatments—child cognitive behavio…

This study tested whether playing a specially designed multitask game for 25 minutes a day, at least 5 days a week, could improve attention in children aged 8-12 with ADHD. Forty children participated, and researchers measured changes in attention using a computer test called TOV…

This study tested a school program for children aged 7 to 11 with Developmental Coordination Disorder (DCD), which affects movement and coordination. The program combined motor exercises with cognitive tasks like imagining actions and watching movements. Over 10 weeks, 20 childre…

This study tested whether extra tutoring in reading and math can improve skills for first-graders who are behind. 385 students from Nashville public schools were randomly assigned to reading tutoring, math tutoring, combined tutoring, or their usual school program. Tutoring laste…

This study tested a special video game controlled by muscle signals (EMG) to help people who had a stroke at least 6 months ago improve hand movement. Twenty participants with moderate hand weakness played the game using either one hand or both. The goal was to see if this fun tr…

This study tested whether a mild electrical current applied to the scalp for 5 days in a row could help adults who stutter speak more fluently. 36 participants received either real or sham stimulation while doing fluency exercises. Researchers measured changes in stuttering durin…

This study tested a new parenting program called ADAPT for depressed parents of children aged 6 to 10 with emotional and behavioral difficulties. The program combines emotion regulation skills with parenting techniques. The goal was to see if the program is feasible and acceptabl…

This study tested a group program to help parents of children with learning or attention difficulties manage stress. About 28 parents took part in either a mind-body resiliency group or a health education group, both held online. The goal was to see if the program was practical a…

This study tested an app called iTalkBetter for people who have trouble finding words after a stroke. 31 participants used the app to practice naming specific items. The goal was to see if the app could improve word retrieval for those practiced items. This small trial helps unde…

This study tested a summer program called STRIPES, where trained peers helped ninth graders with ADHD get ready for high school. 72 students were randomly assigned to the program or to regular school services. Researchers tracked grades, attendance, and ADHD symptoms to see if th…

This study tested a video-based therapy called Focused Acceptance and Commitment Therapy (FACT) for parents of children with special health needs, like ADHD or autism. The goal was to see if it could reduce stress, anxiety, and depression. 104 parents took part, and the therapy w…

This study tested whether ongoing Tai Chi and mindful movement classes could help children with ADHD improve motor control, attention, and reduce symptoms. Fifteen children took part in one-hour classes twice a week for a year. Researchers measured changes in cognitive control, m…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can improve balance and walking in people with Parkinson's disease. 21 participants received both low- and high-frequency stimulation in a double-blind …

This study tested whether adding a gentle brain stimulation technique (tDCS) to online therapy could help adults with ADHD. 30 participants received either real or fake tDCS alongside a 3-month online therapy program. The goal was to see if the combination improved attention and …

This study tested a gentle electric current (tDCS) on the brain to see if it could help people with a past traumatic brain injury find words more easily. Fourteen adults with long-term word-finding problems took part. They received either real or fake stimulation while doing memo…

This study tested a dynamic blended learning module for 49 people with pulmonary hypertension, a chronic disease causing symptoms like shortness of breath and fatigue. The program included face-to-face education, regular phone follow-ups, and a video from a patient who successful…

This study tested a drug called NOE-105 in 75 adult men who have stuttered since childhood. The goal was to see if it could improve speech fluency without the side effects of older treatments. Participants took the drug or a placebo for 10 weeks, and researchers measured changes …

This study looked at whether a high-intensity exercise program is safe and helpful for people with aphasia (trouble speaking or understanding language) after a stroke. Twelve stroke survivors took part in either a low-intensity or high-intensity exercise program. Researchers meas…

This study tested whether special tinted glasses can reduce visual stress symptoms (like eye strain and reading difficulties) in university students. 72 students with visual stress symptoms wore the glasses and reported their reading speed and symptoms. The goal was to see if the…

This study looked at whether taking Lion's Mane mushroom extract daily for two months can improve memory and attention in healthy, working women aged around 40-60. Participants took either the extract or a placebo pill and completed thinking and memory tests at several points. Th…

This study tested a special sleep program for teenagers with ADHD who also have sleep problems. The program combines cognitive behavioral therapy with sleep tips and planning skills. Researchers wanted to see if better sleep could also improve ADHD symptoms and daily life. The st…

This small study tested whether Epidiolex (a prescription CBD oil) can safely reduce symptoms of obsessive-compulsive disorder, hair-pulling, Tourette syndrome, and hoarding. Four adults took the drug for two weeks. The goal was to see if symptoms improved and if the drug was wel…

This study tested whether virtual reality glasses or white noise headphones could reduce pain and anxiety in 48 children with ADHD during dental procedures. The children were distracted with cartoons or white noise while dentists worked. Researchers measured pain through behavior…

This Phase 3 trial tested whether solriamfetol, a drug already approved for sleep disorders, can reduce ADHD symptoms in adults. Over 500 participants took either a daily dose of solriamfetol or a placebo for six weeks. The study measured changes in attention and hyperactivity us…

This study tested whether a therapy called dialectical behavior therapy (DBT) is helpful and acceptable for teens aged 14–17 with fetal alcohol spectrum disorders (FASD). Nine teens and their caregivers took part in a program that included individual therapy, group skills trainin…

This study tested two high-tech teaching methods—AI-assisted learning and virtual reality classrooms—in 90 children aged 8-15 with ADHD. Over 12 weeks, researchers measured changes in ADHD symptoms and thinking skills. The goal was to see if these digital tools can help without m…

This study tested a telehealth program that teaches caregivers skills to manage ADHD-related behaviors and sleep problems in preschoolers aged 3-5 at risk for ADHD. 46 families participated, and researchers measured changes in ADHD symptoms and sleep habits. The goal is to provid…

This study tested a 10-week peer support program called 'Paths to everyday life' for adults with mental health difficulties. Participants were randomly assigned to either the peer support group plus usual services, or usual services alone. The goal was to see if the program impro…

This small study tested whether a gentle electric current applied to the scalp (tDCS) could improve word-finding in 5 civilians who had a traumatic brain injury more than a year ago. Participants received both real and sham stimulation to see if the real treatment boosted verbal …

This study tested whether a gentle, non-invasive brain stimulation called tDCS could make speech therapy work better for people with aphasia (trouble speaking or understanding language) after a stroke. 23 adults who were at least 6 months past their stroke received speech therapy…

This study looked at whether two types of structured exercise—Gince Zumba (rhythm-based aerobic dance) and Square Stepping (patterned steps on a mat)—could improve thinking, movement, and behavior in 51 children with ADHD. Kids were randomly assigned to one of the exercise groups…

This study tested whether a probiotic supplement called Lactobacillus plantarum PS128 can improve tic symptoms and quality of life in children with Tourette's syndrome. 121 children aged 4-18 took part. The main goal was to see if PS128 reduces tic severity and related emotional …

This study tested a 10-week program of biofeedback and breathing exercises in children and teens aged 6-18 with ADHD. The goal was to see if these techniques could reduce ADHD symptoms and improve heart rate variability. The small, completed trial involved 12 participants and use…

This study tested the Triple P parenting program for mothers of children aged 6-13 with ADHD. The program teaches strategies to reduce behavior problems and boost mothers' confidence. 67 mothers took part, with some receiving the program and others not. Researchers measured chang…

This study tested whether adding art therapy to standard speech rehab could help people who recently had a stroke and now have trouble speaking (aphasia). Fifteen participants received 12 art therapy sessions alongside their usual therapy. Researchers used brain scans to see if a…

This study tested a web-based app called Gotcha! designed to help people with mild-to-moderate dementia remember names of people they know. 48 participants practiced daily for 6 weeks using a tablet at home. The goal was to see if the therapy improves name recall and whether it c…

This study tested whether a gentle brain stimulation technique called tACS, combined with speech training, can improve the ability to repeat words in people who had a stroke. 28 adults with aphasia received either real or fake stimulation for 20 minutes daily over 10 days. Resear…

This study tested a new medication called CTx-1301 (dexmethylphenidate) for children and teens aged 6 to 17 with ADHD. The goal was to see if it reduces ADHD symptoms better than a placebo. 103 participants took either the drug or a placebo, and researchers measured changes in AD…

This small study tested whether adding mild brain stimulation (tDCS) to a computer-based naming therapy helps Cantonese-speaking adults with aphasia after stroke find words more quickly and accurately. Six participants completed two 5-day therapy blocks—one with real stimulation …

This study looked at whether stimulant medication can reduce loss of control eating in children aged 8 to 13 with ADHD. Ten children were followed for 3 months after starting stimulants. Researchers measured changes in eating episodes and behaviors to see if treating ADHD symptom…

This study looked at whether high-dose omega-3 fatty acids can reduce ADHD symptoms in children aged 6-12 who have high inflammation levels. Fifteen children took omega-3 supplements for 12 weeks. Researchers measured changes in ADHD symptoms and inflammatory markers to see if om…

This study tested a safe, noninvasive treatment for memory and word-finding problems in Gulf War veterans. 93 veterans received either real or fake (sham) brain stimulation over 10 sessions. The goal was to see if the stimulation improved their ability to recall words and speak m…

This study tested a smartphone app called FMF Connect for parents and caregivers of children with fetal alcohol spectrum disorders (FASD). The app provides helpful information and peer support to manage children's behavior. 129 parents participated, and researchers measured chang…

This study tested a therapy program called EMT en Español for Spanish-speaking toddlers (30-36 months old) with language delays. The program uses play and daily routines to help children learn words and sentences. 81 families took part, with some receiving the therapy and others …

This study tested a therapist-guided online program called AMOR for pregnant women and new mothers with ADHD. 31 participants listened to podcasts and attended online group sessions. The goal was to see if the program was easy to use and helpful for managing ADHD, stress, anxiety…

This study tested whether a smartphone app with speech exercises could help stroke survivors who have slurred speech (dysarthria). 44 people used the app for 30-60 minutes a day, 5 days a week, for 4 weeks. Researchers measured how understandable their speech was and how the cond…

Nearly 90% of people with Parkinson's disease experience speech problems. This study tested a home-based program combining speech exercises and physical activity, delivered via telemedicine, to improve speech intelligibility. 104 veterans with Parkinson's and speech impairment pa…

This study tested whether playing a dance-based video game (Just Dance 2024) could improve attention, mood, and self-control in young adults with ADHD. Sixty-nine participants aged 18-24 were randomly assigned to dance gaming, stationary biking, or music listening for 30 minutes.…

This study tested whether a virtual reality (VR) program can help young adults aged 18-25 with ADHD concentrate better while studying or doing homework. Sixty participants used a VR headset, with some also receiving real-time feedback on their focus levels. The goal was to see if…

This study tested a combined exercise program (aerobic, balance, coordination, and strengthening) in 30 children aged 7–12 with ADHD. The goal was to see if exercise improves motor skills, physical fitness, and thinking. The program lasted several weeks and included warm-up, main…

This study tested a parenting program called the Nurtured Heart Approach to see if it could reduce ADHD symptoms like inattention and hyperactivity in children ages 6 to 8. Parents or guardians of 104 children with or suspected of ADHD were randomly assigned to either start the p…

This study tested a new parent support program delivered via text messaging. The program includes six educational videos teaching strategies to help children with ADHD-like behaviors handle daily transitions. 52 parents of children aged 4-10 participated. The study measured how m…

This study tested whether a special diet that removes certain foods (oligoantigenic diet) can reduce core ADHD symptoms in children aged 6 to 16. Fifty children with ADHD were randomly assigned to either a regular healthy diet or the restricted diet for three months. Researchers …

This pilot study tested whether combining a mild brain stimulation technique (tDCS) with intensive language therapy can help people with non-fluent aphasia after a stroke. Ten participants received both real and sham stimulation during therapy sessions. The goal was to see if the…

This study tested four different doses of SPN-810 (molindone) in 78 children aged 6 to 12 with ADHD and serious conduct problems. The main goal was to see if the drug is safe and tolerable. Researchers measured behavior changes using a special rating scale. The trial is complete,…

This study tested a light therapy called transcranial photobiomodulation (tPBM) to see if it could safely reduce autistic traits and ADHD symptoms in children and teens. 38 participants aged 9 to 17 with ADHD and at least moderate autism symptoms received the treatment. The goal …

This study tested a program called PRISM that teaches stress management, goal-setting, and coping skills to adolescents and young adults (ages 12-24) with advanced cancer. Researchers wanted to see if it could improve quality of life and reduce anxiety and depression. The program…

This study tested whether using a special listening device (FM system) in class for one school year could improve reading and language skills in 71 Chinese children aged 7–11 with dyslexia. Half the children used a real device, and half used a sham device that looked the same but…

This study looked at whether adding music activities like playing harmonica and drums to occupational therapy can improve attention and thinking skills in children with ADHD. Thirty-nine children aged 6 to 17 took part. After six weeks, both standard and music-based therapy helpe…

This study tested whether adding in-home decluttering practice to a group workshop (Buried in Treasures) helps people with hoarding disorder. 41 adults aged 18-70 took part. The goal was to reduce clutter, difficulty discarding, and excessive acquiring. Results were measured usin…

This study tested whether a mild electrical current applied to the front of the brain (tACS) could improve speech and thinking in people with Parkinson's disease. 28 participants received either real or fake (sham) stimulation for 20 minutes daily over two weeks. Researchers meas…

This study tested whether methylphenidate, a drug often used for ADHD, can help children aged 6 to 12 with childhood apraxia of speech speak more clearly. The trial involved 18 children who took the drug or a placebo in a crossover design. The main goal was to see if the drug imp…

This study tested whether a structured program of therapeutic play activities could improve motor adaptive behavior in 20 Egyptian children aged 5-9 with mild intellectual disability. The children took part in 24 play sessions over 2 months, focusing on core strength, coordinatio…

This study tested whether a structured physiotherapy program—including breathing exercises, balance training, and relaxation techniques—could reduce stress, anxiety, and depression in 117 children aged 6 to 18 with autism or ADHD. Participants were randomly assigned to either the…

This study tested a coaching program for families of young children (ages 1.5 to 4.5 years) with suspected or confirmed developmental delays. The program included regular coaching sessions, online education, and peer support over 18 months. Researchers measured whether this appro…

This study tested a 10-session dog-assisted therapy program for 60 adults with severe mental illness. The goal was to see if spending time with trained therapy dogs could help participants build positive mental health behaviors like communication and socialization. Researchers me…

This study tested speech entrainment therapy (SET) in 80 people with non-fluent aphasia after a stroke. Participants practiced speaking along with an audio-visual computer program for 3, 4.5, or 6 weeks, or received no therapy. The goal was to find the best duration for lasting i…

This study looked at whether atomoxetine, a medication for ADHD, can reduce impulsive behavior in adults aged 18-45 with moderate ADHD. Researchers measured impulsivity using questionnaires after a single dose and after two weeks of daily treatment. The goal was to see if the dru…

This study tested whether a gentle, non-invasive brain stimulation technique called tDCS, combined with language therapy, could improve speech in 23 people with primary progressive aphasia (PPA). Participants received either real or fake (sham) stimulation daily for 10 days. Rese…

This study looked at whether a non-invasive brain training method called neurofeedback can help veterans who have had a mild traumatic brain injury and still suffer from chronic headaches, trouble sleeping, and attention problems. 87 veterans were randomly assigned to receive neu…

This study tested whether a biofeedback video game called Mightier can help children aged 8-12 with emotional dysregulation. 183 kids were randomly assigned to play the game at home or receive usual care for 6 months. Researchers tracked symptoms, parent stress, and healthcare co…

This study tested a behavioral therapy called Intention Treatment for Anomia in 32 stroke survivors with aphasia (language impairment). The therapy uses a left-hand circular gesture to engage the brain's intention mechanisms and improve word retrieval. Researchers looked at how o…

This study tested a program where adults with aphasia (a language disorder often from stroke) learn to train dogs using positive reinforcement. The goal was to see if this boosts quality of life, confidence, and social engagement. Seventeen participants completed the program, and…

This study tested whether a gentle electrical current applied to the brain (tDCS) can improve language when combined with speech therapy in people with primary progressive aphasia (PPA), a condition that slowly damages language abilities. 76 adults with two types of PPA received …

This study tested whether combining transcranial magnetic stimulation (TMS) with language therapy helps people with chronic aphasia—a language disorder after stroke—speak better. 86 participants received either real TMS or a sham version, plus language therapy, over two weeks. Th…

This study looked at whether giving iron supplements to children with ADHD, restless legs syndrome, and low iron levels could improve their symptoms. Twelve kids aged 10-15 took iron for 3 months. Researchers measured changes in brain iron, blood iron, and symptoms using sleep mo…

This study tested whether a gentle electrical current applied to the scalp (tDCS) during speech therapy could help people with chronic aphasia—a language disorder after stroke—recover their ability to name objects and read words. Twenty-five adults with long-term aphasia received…

This study looked at whether Auri Super Mushroom Daily Gummies can help adults aged 30 and older who struggle with forgetfulness, lack of focus, low energy, and low mood. Over 8 weeks, 35 participants took two gummies each day and completed tests and surveys about their thinking,…

This study tested a non-medication sleep program for 88 adults with depression, bipolar disorder, or ADHD who also had insomnia. Participants received either the sleep program or standard sleep hygiene advice. The goal was to see if the program could improve sleep quality and red…

This study looked at whether playing in virtual reality (VR) can improve cognitive skills like attention and problem-solving in children with ADHD. Fourteen children aged 7-12 with stable medication took part. Researchers used a special test to measure thinking abilities before a…

This pilot study tested whether a daily dose of EGCG, a natural compound found in green tea, could improve cognitive performance in 36 children aged 7 to 14 with fetal alcohol syndrome. The children took EGCG for one year and had their thinking skills measured at the start, at 6 …

This study tested whether listening to white noise or seeing visual pixel noise can improve attention in children with ADHD. Sixty children, some with ADHD and some without, completed eye-tracking tasks while exposed to these noises. The goal was to see if the noise could help th…

This study tested a 6-week supervised physical activity program for university students dealing with mild-to-moderate mental health issues like stress, anxiety, or feeling isolated. Seventeen students took part in group exercise sessions including walking, aerobics, and strength …

This study tested a speech therapy technique called speech entrainment, where people with aphasia practice speaking along with a recorded voice in real time. Thirty adults with aphasia participated, either in person or at home. The goal was to see if this practice improves how in…

This study tested a smartphone app called SRAVI that reads lip movements and turns them into words on a screen. It was used by 31 adult patients in acute or critical care who had a tracheostomy and could not speak. The goal was to see if the app could help them communicate better…

This study tested a digital therapeutic device that combines driving simulations and memory exercises to improve attention and reduce hyperactivity in children with ADHD. About 120 children aged 6 to 12 took part, with some using the active device and others a placebo version. Th…

This study looked at whether the SNOO Smart Sleeper, which plays white noise and gently rocks, helps preterm infants sleep more peacefully and have better vital signs compared to a traditional bassinet. Twenty preterm infants in the NICU each spent two three-hour sessions sleepin…

This study tested whether adding a therapy dog to standard social skills training could help children with ADHD. Thirty-nine children took part, some receiving dog-assisted sessions and others only social skills training. Researchers measured ADHD symptoms, self-esteem, and stres…

This study tested whether trained dogs can help children who miss a lot of school. 64 students in grades 3-9 with at least 15% absence were randomly assigned to receive either dog-assisted support or standard teaching for 30 minutes twice a week for 10-12 weeks. The goal was to s…

This study tested whether a self-hypnosis smartphone app called Hypnotidoo could improve attention and reduce anxiety in children aged 7 to 12 with ADHD who were already taking methylphenidate. The app offers short, screenless audio sessions with stories and breathing exercises. …

This pilot study tested a music breathing therapy for children with ADHD and their caregivers. The therapy involved six weekly group sessions combining music, breathing exercises, and games. The goal was to see if it could boost resilience and reduce emotional and behavioral symp…

This study tested whether showing people a live ultrasound image of their tongue during speech therapy helps them improve faster. It included 18 adults and children with speech problems after surgery or brain injury. They compared therapy sessions with and without the ultrasound …

This study tested a 12-week program where children with ADHD worked with horses as part of occupational therapy. The goal was to see if it helps with emotional control, daily functioning, and participation in activities. Fifty children aged 6 to 12 took part, and researchers meas…

This study tested whether a smartphone app (BHQ) can reliably monitor social anxiety symptoms in adults, and whether a computer-based attention training called gaze-contingent music reward therapy (GC-MRT) reduces those symptoms. Forty adults with social anxiety disorder used the…

This pilot study tested whether a voice therapy program called LSVT-Loud, usually done in a clinic, can be delivered effectively via video calls for people with multiple sclerosis (MS). Twenty participants with MS who had voice problems received the therapy either at home or in t…

This pilot study tested a program called PRE-CARE for 54 low-income families of preschoolers with ADHD symptoms. The program helps families find and enroll in community resources like food assistance or housing support. Researchers wanted to see if this approach could reduce ADHD…

This completed study from the National Institute of Neurological Disorders and Stroke aimed to better understand how the brain controls movement and what goes wrong in movement disorders like Parkinson's disease, Tourette's syndrome, and dystonia. Over 1,200 adults—both patients …

This study investigates how different language treatments affect both language skills and brain function in people with aphasia, a condition that impairs the ability to speak, understand, read, or write after a stroke. Participants will receive therapy targeting naming, spelling,…

This study looks at whether children with ADHD are more likely to have very flexible joints (benign joint hypermobility) and if a certain blood marker differs. Researchers will compare 171 children aged 6 to 12—some with ADHD and some without—using physical exams and blood tests.…

This study tested a two-day training program designed to help newly graduated nurses speak up about patient safety concerns. 76 nurses from a hospital in Ankara, Turkey, were split into two groups: one received the training, the other did not. Researchers measured changes in comm…

This study looked at whether asking children with developmental language disorder to repeatedly recall new words helps them learn better than just hearing the words. Twenty-seven 4- and 5-year-olds learned made-up words during storybook reading. The goal was to see if retrieval p…

This study tests a tool called the Cultural Formulation Interview-Engagement Aid (CFI-EA), designed to help clinicians and patients from different cultural backgrounds communicate better. The goal is to see if using this tool improves patient satisfaction and keeps people in trea…

This study looked at how different ways of communicating (like talking in person vs. texting) change brain activity. Researchers used fMRI scans on 30 healthy young adults while they watched videos of different communication styles. The goal was to see if each style uses a differ…

This study tested whether a 10-week recovery program, co-led by a peer with mental illness and a professional, is feasible for people with mental illness in Taiwan. Twenty participants completed the program, which focused on recovery concepts, strengths, and goal setting. Researc…

This study tested whether a computer program could predict which older patients (over 75) would have unnecessary days in the hospital. Researchers analyzed electronic health records from 102 patients in an acute geriatric unit. The goal was to create an algorithm that flags when …

This study looked for hidden genetic changes in 10 children with developmental delays who had a balanced chromosomal translocation (a rearrangement of DNA that appears normal under a microscope). Researchers used high-resolution DNA microarrays to check for tiny missing or extra …

This study looked at how Doose syndrome, a rare form of epilepsy, affects children's ability to learn and develop. Researchers followed 9 children and asked their parents about the disease's impact on school and daily life. The goal was to better understand the link between seizu…

This study looked at 128 physiotherapy students to see if taking an academic literacy class helped with their reading, writing, and thinking skills. Researchers compared students who took the class to those who did not using surveys. The goal was to understand if such education b…

This study looked at two ways to assess ADHD in children aged 8-17: a brief protocol (medical history, interview, rating scales) and a comprehensive one that also includes neuropsychological testing. Researchers wanted to see if the shorter method is as reliable, valid, and cost-…

This study looked at whether an adaptive e-learning course on urgent medical conditions could reduce anxiety and improve skills in junior doctors starting work in emergency departments. 233 new doctors were randomly assigned to either take the course in their first six weeks or r…

This study looked at 132 teenagers with Tourette syndrome to understand how their brains and thinking skills change during adolescence. Researchers used brain scans (MRI), magnetic pulses (TMS), and computer tests to measure brain connections, control, and decision-making. The go…

This completed study tested different messages to see which ones make adults more willing to get the HPV vaccine, which prevents certain cancers. Over 5,300 adults aged 18-45 were randomly assigned to read one of five theory-based messages or a control message. The goal was to fi…

This study looked at whether a therapy called FAST (Forensic Outpatient Systemic Therapy) helps teens aged 12-21 with conduct disorder or aggressive behavior. The therapy involves weekly sessions with the teen and their caregivers for several months. Researchers measured changes …

This study tested a web application called PRATICAdr 2.0, designed to help healthcare workers on sick leave due to common mental disorders like depression or anxiety return to work. The app helps coordinators track progress and improve communication. Researchers compared workers …

This study looked at how the brain uses 'noise'—random variations in brain cell activity—to help people learn. Researchers tested 47 healthy adults using brain scans and computer models to see if this noise makes learning faster or more efficient. The goal was to understand a bas…

This study tested whether artificial intelligence (AI) can realistically simulate conversations between a therapist and a person with a mental health problem. Researchers used 520 simulated sessions to see if the AI could follow proper therapy techniques. The goal is to use these…

This study compared virtual reality (VR) training to standard classroom teaching for nursing students learning how to triage in a mass casualty incident. 100 nursing students took part. The goal was to see if VR helps them triage more accurately and quickly.

This study looked at brain activity in the frontal cortex of 14 people with Tourette syndrome using a 24-hour portable EEG. Participants pressed a button each time they had a tic, so researchers could compare brain signals with and without tics. The goal was to identify which bra…

This study looked at how thinking skills and brain activity differ in people who self-harm compared to those who don't. Researchers interviewed 316 adults and gave them thinking tests, with some also having brain scans. The goal was to better understand self-harm to help create m…

This completed study looked at sleep problems in over 1,100 children and adults with specific learning disabilities (like dyslexia or dyspraxia), with or without ADHD. Participants filled out online questionnaires about their sleep habits. The goal was to find out how common diff…

This study looked at how healthy adults decide where to look in a busy scene, like finding Waldo in a crowded picture. Researchers tracked eye movements while people viewed images with different colors and motion to understand how the brain highlights important spots. The goal wa…

This study looked at two ways to help children with Developmental Language Disorder (DLD) improve their grammar: recast therapy (where a therapist corrects the child's speech) and reading specially designed stories. Researchers worked with 137 children aged 4-9 to see how well th…

This study looked at whether solving crossword puzzles helps nursing students learn how to give intramuscular injections. 140 students took part, with some solving puzzles about the skill before practicing. Researchers measured their motivation, mental effort, and skill performan…

This study looked at brain activity in adults with ADHD while they performed tasks that required stopping an action. Researchers used EEG to measure electrical signals in the brain. The goal was to understand the brain processes behind impulse control problems in ADHD. No treatme…

This study looks at 128 children who were part of an early intervention program in infancy and are now teenagers. Researchers measure brain activity, stress responses, and behaviors like risk-taking and mood to see if early help made a difference. No new treatment is given; this …

This study looked at how centanafadine, a potential ADHD treatment, affects the body when taken with common stimulant medicines. Forty healthy adults took part to measure changes in blood pressure, heart rate, and drug levels. The goal was to understand possible interactions, not…

This pilot study tested whether personalized medication experiments could help teens with ADHD and their parents make better decisions about future medication use. Thirty-one parent-teen pairs (teens aged 11-15) completed a medication experiment chosen together. The goal was to s…

This study looked at how nicotine from dissolvable tablets affects attention in 40 adults who occasionally use nicotine pouches. Participants tried tablets with different nicotine amounts (0 to 2 mg) and took attention tests after 15 minutes and 2 hours. The goal was to understan…

This study examined how the frequency of speech therapy sessions affects speech and language outcomes in children. Researchers followed 39 children with speech or language disorders who were receiving individual therapy. They measured changes in articulation, vocabulary, and over…

This study looked at whether being socially excluded (ostracized) affects the memory of children with ADHD. Twenty-four kids played a computer ball-tossing game where they were eventually left out, and their memory was tested before and after. The goal was to see if emotional dys…

This study tested a communication tool called 'Best Case/Worst Case' for older adults with advanced kidney disease. Doctors were trained to discuss best, worst, and most likely outcomes for treatment options. The goal was to see if this approach helps patients receive more pallia…

This completed study at Rutgers University looked at how the brain and body communicate in 30 people with conditions like autism, ADHD, Alzheimer's, and Parkinson's. Participants performed natural movements like walking and pointing while their brain, heart, and motion signals we…

This study tested a smartphone app that gives parents of children with ADHD quick tips and feedback on their parenting. 34 families took part, and the app sent messages at random times to see if parents used more positive skills right after. The goal was to see if parents liked t…

This study looked at whether children with dyscalculia (a math learning disability) have trouble automating counting procedures rather than recalling math facts. Three children aged 8–11 solved simple addition problems over three years while researchers measured their response ti…

This study tested simple toolkits to encourage women living with HIV in Ghana to collect their own samples for HPV testing, which can help prevent cervical cancer. About 108 women took part, and the researchers checked if they completed and returned the self-sampling kit or got a…

This study tested whether an artificial intelligence tool could help therapists deliver better behavior therapy to minority adolescents with ADHD. Researchers worked with three community mental health agencies and 51 teens. Therapists received either AI-assisted supervision or st…

This study looked at how the brain tracks speech sounds in healthy young adults. Researchers measured brain waves in English and Mandarin speakers to see how language experience and attention affect sound processing. The goal was to better understand the brain's role in hearing, …

This pilot study tested whether using artificial intelligence to personalize educational games can help nursing students learn better about pregnancy and childbirth. 38 second-year nursing students were split into two groups: one received a standard gamified lesson, and the other…

This study looked at how the brains of people with aphasia (a language disorder after stroke) and healthy people work together during gestures. Using EEG, researchers measured brain synchronization while participants watched and copied different types of gestures. The goal was to…

This study tested a program called Recovery Bridge, where trained peer specialists (people with lived experience of mental illness) helped veterans leaving a psychiatric hospital connect to outpatient care and community life. Fifteen veterans took part to see if the program was f…

This study looked at whether giving 7-11-year-old children in Shanghai a daily breakfast with fruits and vegetables could improve their thinking, mood, and attention. Over 250 kids took part, receiving a balanced breakfast every day for 12 weeks. Researchers measured changes in c…

This study looked at whether a blockchain-powered electronic portfolio helps nursing students track their skills and keep learning. 72 third-year nursing students used either a blockchain e-portfolio or a standard one during their clinical rotation. Researchers measured their cli…

This study looked at whether digital services like smartphone apps can help people with psychosomatic disorders continue their treatment during the COVID-19 pandemic, when social distancing and hygiene rules limit in-person therapy. About 2000 patients from clinics took part, usi…

This study looked at whether a special reading program called Reach Out and Read (ROR) could help parents read more often to their babies in the Neonatal Intensive Care Unit (NICU). Researchers surveyed 101 parent-infant pairs before and after the program was introduced. The goal…

This completed study looked at 400 people with both heart disease and a mental health condition (like depression or anxiety). Researchers used questionnaires, blood tests, and imaging to find shared risk factors and biological markers. The goal was to better understand how these …

This study looked at whether the design of a common ADHD screening questionnaire (the ASRS) influences how people answer. Researchers wanted to see if shading and grouping certain answer choices made it easier for patients to guess which responses lead to a positive screen. 587 a…

This study looked at whether a new drug called EB-1020 has abuse potential in 80 healthy adults who use stimulants recreationally. Participants received single doses of EB-1020, d-amphetamine, or placebo, and rated how much they liked the drug. The goal was to see if EB-1020 prod…

This study tested whether an anti-stigma training program for healthcare providers improves attitudes toward people with mental illness or substance use problems. About 485 staff and clients from six health centers took part, with three centers receiving the training and three no…

This study looked at 15 people with a rare genetic condition called DDX3X syndrome, which can cause intellectual disability and sometimes autism. Researchers used interviews, play-based assessments, and genetic tests to better understand the condition. The goal was to describe th…

This completed study followed 509 children aged 3 to 18 who were taking risperidone or aripiprazole for conditions like schizophrenia or bipolar disorder. Researchers measured weight changes over up to 50 months to understand long-term risks. The goal was to provide better safety…

This study looked at how often insomnia occurs in people hospitalized for psychiatric conditions. Researchers checked 427 patients at 11 hospitals in Switzerland and Germany. They also explored whether age, gender, or type of disorder made insomnia more likely.

This study tested whether a flipped classroom model helps midwifery students learn pregnancy exams better than traditional lectures. 95 students were split into two groups: one used online materials before class, the other had standard teaching. Researchers measured knowledge, pr…

This study looked at whether taking two smaller capsules of centanafadine (a potential ADHD medication) works the same as taking one larger capsule. 44 healthy adults took both versions at different times to compare how the drug enters the blood. The goal was to confirm the doses…

This completed study tested whether a short, non-invasive brain stimulation technique called theta burst stimulation (iTBS) could improve brain circuits involved in tic control. Sixteen people with Tourette syndrome, aged 10 to 21, received either real or sham stimulation. The go…

This study used a non-invasive brain stimulation technique called TMS to temporarily quiet a part of the brain involved in language processing. Researchers then tested how well 42 older youth with dyslexia learned and remembered made-up spoken words. The goal was to understand th…

This study looked at whether using feedback and spacing out practice sessions can help children aged 5 to 9 who are deaf or hard of hearing learn new words more efficiently. Thirteen children took part in word-learning exercises to see which methods worked best. The goal was to f…

This study tested a modified behavioral parent training program for children with ADHD who also have peer problems. The program aimed to increase parent engagement, especially for parents with their own ADHD or depression symptoms. Thirty-three parents participated, and researche…

This completed study looked at whether giving doctors access to genetic tests called FirstStepDx PLUS and NextStepDx PLUS helps them diagnose intellectual disability and developmental delay more accurately and cost-effectively. The study involved 217 pediatric neurologists, devel…

This study looked at whether methylphenidate, a common ADHD medication, changes levels of brain inflammation markers in children aged 6 to 11. Researchers measured three inflammation-related substances in the blood of 42 children before and after 3 months of treatment. The goal w…

This study tested whether midwifery students who practice episiotomy repair in pairs learn better than those who practice alone. 92 students were split into two groups. The paired group worked together on calf tongues, while the control group practiced individually. Researchers m…

This study looked at 105 babies born to mothers who smoked during pregnancy, comparing those whose mothers quit versus those who continued. Researchers checked health indicators like birth weight, Apgar scores, and developmental milestones up to 24 months. The goal is to understa…

This study looked at whether a personalized training program could improve driving skills in 90 teens with ADHD (ages 15-18) who hadn't started driving lessons. Teens were split into three groups: one received the special training, one got educational materials, and one got no in…

This study looked at whether a single dose of methylphenidate (Ritalin) changes how people with both ADHD and alcohol use disorder respond to alcohol-related cues. Thirty-one adults aged 18-25 completed brain scans, EEG, and behavioral tests after taking either the drug or a plac…

This study tested a small-group program called 'Let's Know!' to see if it helps first graders with weak oral language skills. 22 children participated. The program focused on vocabulary, making inferences, and understanding stories. The goal was to see if the program could improv…

This study looked at how speech production helps reading in adults with and without dyslexia. 56 adults completed reading tasks while sucking a lollipop, holding a bite bar, or having their mouth numbed with lidocaine. The goal was to see if these motor tasks change reading speed…

This completed study looked at 500 children aged 5 to 18 to understand how factors around birth, thinking abilities, and social-emotional skills are linked to learning difficulties and developmental disorders like ADHD or autism. Researchers compared children with and without the…

This study explored whether a summer psychosocial program could improve emotional control, behavior, and school readiness in 323 children aged 4-7 with ADHD or disruptive behaviors. Researchers measured changes in emotion regulation, ADHD symptoms, social skills, and academic rea…

This study used brain scans to understand how speech therapy helps children with cleft palate who have trouble speaking clearly. Researchers looked at brain connections and structure before and after therapy in 164 children aged 4 to 16. The goal was to see if therapy changes abn…

This study tested an 8-month program called 'Meaningful Activities and Recovery' (MA&R) for people with mental illness. The program helps people take part in activities that matter to them. 139 adults took part to see if the program improves activity engagement, recovery, and qua…

This study looked at how emotions influence speech coordination in 68 preschool children, some who stutter and some who don't. Kids repeated a phrase after seeing emotional or neutral pictures. The goal was to understand how emotional reactions and speech control interact in earl…

This completed study looked at whether playing white noise during reading and writing tests helps children aged 8-13 with ADHD and specific learning disorders. Thirty children took the same tests twice—once with white noise and once without—to see if the sound improved their spee…

This study looked at 263 severely injured trauma patients to find out how often they develop early blood clotting problems (called trauma-induced coagulopathy) and excessive clot breakdown (hyperfibrinolysis) within the first hour of arriving at the emergency room. Researchers us…

This study tested a resource package designed to help caregivers use behavioral interventions for children showing hyperactive, inattentive, or impulsive behaviors. Twenty caregivers of children in grades K-5 in the Philadelphia area used the package at home. The research team co…

This study looked at 188 children (ages 0-18) with Fetal Alcohol Spectrum Disorders (FASD) in Reunion Island to better describe the condition and find a unique "epigenetic signature" in their DNA. Researchers collected blood and cheek swabs from a small group of children with FAS…

This study tested a program called iCOT to improve how occupational therapy interns communicate with patients in mental health settings. The program included online training and feedback from patients, supervisors, and experts. Researchers compared interns who received iCOT to da…

This study looked at whether using games in class helps physiotherapy students learn how to treat patients who are afraid of movement (kinesiophobia). About 94 students took part, with some learning through games and others through standard teaching. The goal was to see if the ga…

This small, completed study looked at how many Hydrus microstent surgeries glaucoma fellows need to perform before they become skilled. Researchers graded videos of surgeries from 5 fellows at three eye centers. The goal was to find the average number of cases needed to reach an …

This study looked at 84 children with ADHD to see if the type of ADHD they have affects their pain threshold. Researchers measured how much pressure caused discomfort in different body areas. The goal was to understand if certain ADHD subtypes are linked to chronic pain or differ…

This study tested whether a systematic phone call from a medical student, supervised by a general practitioner, could reduce hospitalizations in patients with chronic heart or mental health conditions during the COVID-19 lockdown in France. Over 22,000 patients aged 70 and older …

This study tested whether playing a Gimkit game after a regular lab class helps first-year nursing students learn about the respiratory system. 114 students were split into two groups: one got the game, the other didn't. Researchers measured their motivation and test scores to se…

This study compared two ways of teaching medical students to use microscopes: the traditional method with physical microscopes and a newer digital method using computers. 350 fourth-year medical students took part to see which approach helped them learn better. The goal was to fi…

This study looked at how the brain processes speech sounds in 25 people with language impairment or hearing loss. Researchers used e-learning games or hearing aids to see if these interventions change brain activity. The goal was to better understand the underlying problems and g…

This completed study looked at how people with Tourette syndrome perceive their own actions compared to external forces. Researchers measured a phenomenon called sensory attenuation, which reflects how the brain integrates sensory feedback with motor commands. The study involved …

This study looked at whether adults with ADHD are more likely to relapse into drinking after completing a detox program. Researchers followed 113 people for 12 weeks, using interviews and questionnaires to assess ADHD and other mental health conditions. The goal was to see if ADH…

This study tested whether a mild electrical current applied to the scalp (tDCS) could temporarily improve attention and self-control in adults with ADHD. 83 people, including those with ADHD and healthy volunteers, completed tasks measuring focus and decision-making while receivi…

This study looked at how children with ADHD perform when they have to do two tasks at the same time, like walking while naming animals. Researchers compared 60 children (some with ADHD, some without) to see differences in motor and thinking skills. The goal was to better understa…

This study tested a 15-week reading program called Sit Together and Read (STAR) for 20 children aged 4-5 who are being raised by relatives (kinship caregivers) because their parents used opioids. The program was designed to improve children's reading skills and help caregivers fe…

This pilot study tested whether AI-generated daily written summaries can help ICU clinicians communicate better with families. Clinicians edited the AI summaries before giving them to families. The study involved 27 participants and measured how acceptable and feasible this appro…

This study tested how different capsule versions of the ADHD drug centanafadine are absorbed in the body. 174 healthy adults took part to see if a single high-dose capsule works the same as two lower-dose capsules, and whether food changes absorption. No treatment was given; the …

This study uses eye-tracking technology to see how children with language development disorders process and remember sounds compared to typically developing children. Researchers will track eye movements while children perform language tasks to understand how their brains handle …

This study looked at whether asking children with Specific Language Impairment (SLI) to talk about new words during storybook reading helps them learn and remember those words better. 48 kindergarteners aged 5-6 took part. Researchers compared three versions of book reading with …

This completed study at the NIH enrolled 96 children with known or suspected genetic disorders, including autism and Fragile X syndrome. The main goal was to give clinic staff hands-on experience and explore new research ideas. Participants received medical exams, lab tests, and …

This study tested different parts of a family navigation program to see which ones work best for helping low-income and minority families get mental health services for their children. 312 children aged 3-12 who showed signs of behavioral health concerns took part. The goal was t…

This study tested two approaches to help healthcare providers communicate better with patients who have speech, language, voice, or hearing disabilities. One approach trained healthcare teams on communication strategies, and the other added a patient prompt list that lets patient…

This study looked at whether giving students with ADHD extra time on exams actually helps them perform better. Researchers tested 103 students, some with ADHD and some without, giving them either 25% or 50% more time to complete a test. The goal was to see if extra time improves …

This study tested a new way for doctors and families to talk about ICU care for very sick patients with advanced illnesses. Instead of continuing treatments indefinitely, they used 'time-limited trials' — agreements to try treatments for a set period and then check if the patient…

This study followed 500 children with and without developmental delays for five years. Researchers measured their quality of life and participation in activities, and analyzed their genes. The goal was to understand what factors help children thrive. No treatments or intervention…

This study used artificial intelligence to predict how engaged people would be in online therapy and how much their symptoms would improve. Researchers analyzed data from over 6,600 adults who took part in a digital psychotherapy program. The goal was to create fair and accurate …

This study tested a program to help kindergarten teachers recognize that some children may be mistakenly diagnosed with ADHD simply because they are younger than their classmates. 62 children who were born just before the school cutoff date took part. Teachers learned about this …

This study looked at how a specific reading program, called Seeing Stars, affects the brains of 90 children with dyslexia. Researchers used brain scans to measure changes in white matter and a region linked to word recognition. The goal was to understand why some children improve…

This study tested a family-based telehealth program for teens aged 12–18 involved with child welfare and their caregivers. The program aimed to improve communication and emotion regulation through weekly video sessions. 93 participants were enrolled, and researchers measured chan…

This completed study with just 2 participants aimed to find out who responds best to two different word-finding therapies for aphasia. Both treatments focus on the sounds of words to improve naming. The goal is to learn which therapy helps which person, so future treatment can be…

This study explores how parents' own language skills influence the quality of early language interactions with their children, especially those with language delays or autism. Researchers trained 156 parents using a program called Enhanced Milieu Teaching, which teaches responsiv…

This study looked at whether whole genome sequencing (a complete read of a person's DNA) can help diagnose leukodystrophies, a group of rare brain diseases that are hard to identify. Researchers enrolled 236 children with white matter abnormalities on brain scans but no known gen…

This study tested whether a tool called "Best Case/Worst Case" helps doctors have better conversations with severely injured older adults (age 50+) and their families about treatment options. Researchers compared communication quality before and after surgeons learned to use the …

This study created and tested a mobile app called VetEd for student veterans dealing with mental health issues like depression, PTSD, or anxiety. The goal was to help them manage academics, mental health, and find resources. Researchers worked with 13 veterans to see if the app w…

This study looked at how toddlers with developmental language disorder (DLD) learn sound patterns. Researchers tested 105 toddlers to see if adding meaning to sounds helps or hinders learning. The goal is to better understand language difficulties and create earlier, more effecti…

This study looked at how children with developmental language disorder (DLD) learn patterns in sounds and grammar. Researchers tested over 900 adults and children to see if a general difficulty with learning sequences links problems in both areas. The goal is to create better ear…

This study looked at how much speech therapy is best for children aged 5 to 8 with language impairment. Fifty-nine kids were randomly assigned to receive therapy either once a week for 2 hours or four times a week for 30 minutes, over 10 weeks. The goal was to see which schedule …

This completed study looked at 224 adults who already had at least one psychiatric condition to see how many also had undiagnosed ADHD. Researchers measured how often ADHD was missed and tracked quality of life in those diagnosed. The goal is to highlight the need for better dete…

This study tested a professional development program for teachers in Early Head Start classrooms. Ten teachers attended workshops and received weekly coaching to improve their use of evidence-based practices. The goal was to see if the training was feasible and acceptable, and wh…

This study tested whether a peer mentoring program could improve therapeutic communication skills in pediatric nursing students. 73 students were randomly assigned to either receive peer mentoring or standard lessons only. Researchers measured communication skills using a scale a…

This study tested whether children with ADHD are more likely to produce false memories compared to children without ADHD. Researchers used a word-list task called the DRM paradigm, where children heard lists of related words and later recalled them. The study involved 28 children…

This study looked at whether the way a physiotherapist talks about virtual reality (VR) affects how chronic pain patients view the treatment. Researchers showed 115 patients one of two videos: one with positive, encouraging words about VR, and another with negative, discouraging …

This study tested whether a type of brain stimulation called intermittent theta burst stimulation (iTBS) can improve working memory in 14 adolescents with ADHD. Each participant received one session each of iTBS, standard TMS, and fake TMS. Brain activity was measured before and …

This completed study tested a device called EarliPoint that uses eye-tracking to monitor changes in children with autism spectrum disorder (ASD) or developmental delays. Researchers followed 325 children aged 15-84 months over 180 days to see if the device could detect improvemen…

This study aimed to create and test a new scale called TD-STIGMA to measure stigma and discrimination in children and young adults with chronic tic disorders, including Tourette syndrome. Researchers worked with 43 participants, including people with tics and their caregivers, to…

This study followed 50 children who received cochlear implants, measuring their brain's electrical responses to sounds and comparing them with speech and language test results over three years. The goal was to see if certain brain wave patterns could predict how well a child deve…

This study looked at 558 people with congenital hypothyroidism, a rare thyroid condition found in newborns. Researchers examined their genes, medical images, and health records to find links between genetic changes and the type or severity of the disease. The goal is to improve e…

This study looked at whether the ADHD Rating Scale-IV can detect changes in attention problems in children with epilepsy. Researchers followed 173 children aged 6 to 15 who had both epilepsy and ADHD. They compared scores over 12 to 16 weeks in treated versus untreated children t…

This study tested whether a non-invasive brain stimulation technique called repetitive transcranial magnetic stimulation (rTMS) can reduce abnormal brain activity and improve language in children with benign epilepsy with centrotemporal spikes (BECTS). Twenty-two children receive…

This study used brain scans and behavioral tests to explore why people with Tourette syndrome often act impulsively. Researchers compared 80 patients (40 on medication, 40 not) with 40 healthy volunteers. The goal was to map brain connections linked to impulsivity, which could he…