Tourette syndrome study probes the Brain's sense of Self-Made actions
NCT ID NCT07290920
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This completed study looked at how people with Tourette syndrome perceive their own actions compared to external forces. Researchers measured a phenomenon called sensory attenuation, which reflects how the brain integrates sensory feedback with motor commands. The study involved 60 participants, including both people with Tourette syndrome and healthy controls, to better understand the link between sensorimotor integration and symptom severity.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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60 people
The number who actually took part.
- Started
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Mar 2025
- Finished
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Dec 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population will include adult participants aged 18 to 65 years, comprising two groups: individuals diagnosed with Tourette Syndrome (TS) and healthy control participants. The Tourette group will consist of patients meeting DSM-5 diagnostic criteria for Tourette Syndrome, recruited through specialized neurological and neuropsychiatric clinics. Healthy controls will be recruited from the general population and will be matched to the TS group for age, sex, and education level.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: For Tourette Syndrome group: * Clinical diagnosis of Tourette Syndrome (TS) according to DSM-5 criteria * Age between 18 and 65 years * Ability to understand and comply with study procedures * Written informed consent provided For Healthy Control group: * No current or past history of neurological or psychiatric disorders * Age between 18 and 65 years * Matched to the TS group for age, sex, and education level * Ability to understand and comply with study procedures * Written informed consent provided Exclusion Criteria: * History of significant neurological disorders (e.g., brain injury or dementia) or major psychiatric disorders (with the exception of conditions commonly associated with Tourette Syndrome, such as Obsessive-Compulsive Disorder, ADHD, depression, and anxiety); * Failure or refusal to provide written informed consent; * Confirmed pregnancy (self-reported) and/or breastfeeding.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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IRCCS Ospedale Galeazzi-Sant'Ambrogio
Milan, Italy, 20100, Italy
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Other studies related to the condition(s) this trial covers.