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One therapy to tackle two conditions: a trial combines exposure and habit reversal for tourettic OCD

NCT ID NCT07725926

Recruiting now Symptom relief Sponsor: University College London Hospitals Source: ClinicalTrials.gov ↗

First seen Jul 24, 2026 · Last updated Jul 24, 2026

Summary

This trial tests whether a therapy that blends Exposure and Response Prevention (ERP) with Habit Reversal Training (HbRT) can reduce both obsessive-compulsive and tic symptoms in adults with Tourettic OCD — a subtype where OCD and tic disorders overlap. Standard treatments usually target only one condition, but this study asks if tackling both at once works better than either therapy alone. Forty adults with Tourettic OCD will receive 12 weekly sessions of the combined therapy, and their symptom changes will be measured at the end of treatment and during follow-up.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
a combination of Exposure and Response Prevention (ERP) and Habit Reversal Training (HbRT), two behavioural therapies
What this could lead to
If the combined therapy works, it could offer a single treatment that addresses both OCD and tic symptoms at once, rather than treating each condition separately.
What could go wrong
This is a small, early-stage trial with only 40 participants, so results may not apply to everyone. Behavioural therapies require active participation and may not work for all individuals.

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Conditions

The condition(s) this trial relates to.

chronic tic disorder obsessive-compulsive disorder obsessive-compulsive personality disorder tic disorder Tourette syndrome transient tic disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

GILLES DE LA TOURETTE SYNDROME OBSESSIVE - COMPULSIVE DISORDER TIC DISORDER, CHRONIC MOTOR OR VOCAL TIC DISORDER, COMBINED VOCAL AND MULTIPLE MOTOR TIC DISORDERS TOURETTE DISEASE TOURETTE DISORDER TOURETTES SYNDROME

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • University College London Queen Square Institute of Neurology

    RECRUITING

    London, London, WC1N 3BG, United Kingdom

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

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