Could a plant extract ease ADHD in adults? new trial results are in

NCT ID NCT05202327

Completed Symptom relief Sponsor: BioLite, Inc. Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This Phase II trial tested PDC-1421, a capsule made from a plant extract, in 99 adults with ADHD. Participants were randomly assigned to receive the capsule or a placebo for up to 8 weeks. The goal was to see if the treatment could reduce ADHD symptoms and to check its safety.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: PDC-1421 (extract of Radix Polygalae, a plant-based capsule)
What this could lead to: If it works, this could point toward a new plant-based option to help ease ADHD symptoms in adults.
What could go wrong: This is an early Phase II trial with only 99 people, so results may not apply widely. The treatment may not work better than placebo, and side effects are still being studied.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD) are added.

Our safety recommendation!

By submitting, you agree to our Terms of use

Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ATTENTION-DEFICIT/HYPERACTIVITY DISORDER (ADHD)

Contacts and locations

Locations

Cheng Hsin General Hospital

Taipei, 112, Taiwan
Kaohsiung Chang Gung Memorial Hospital

Kaohsiung City, 83301, Taiwan
Linkou chang Gung Memorial Hospital

Taoyuan, 33425, Taiwan
National Taiwan University Hospital

Taipei, 10002, Taiwan
Taipei veterans General Hospital

Taipei, 112, Taiwan
University of California, San Francisco

San Francisco, California, 94143, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.