Specific developmental disorder

This Phase 3 trial is evaluating how safe solriamfetol is when taken daily over a long period by children and adolescents with ADHD. Participants who completed earlier studies will receive the medication and be monitored for side effects. The goal is to see if this treatment rema…

This trial tests whether a behavioral plan, a language program, or both together work best for kindergarten and first-grade students who are learning English and show ADHD symptoms. About 300 children will be randomly placed into one of four groups: usual school support, language…

This trial investigates whether a long-acting liquid stimulant medication (Quillivant XR) can safely and effectively reduce ADHD symptoms in children with Down syndrome, who are at higher risk for ADHD but often go untreated. The study will compare the medication against a placeb…

This trial tests whether a personalized training program called 'Kleuter Extra' can improve executive functioning—skills like attention, self-control, and planning—in preschoolers aged 4 to 6 who have severe congenital heart disease. Many children with this condition face thinkin…

This trial investigates the long-term safety of ecopipam, a drug that blocks dopamine D1 and D5 receptors, in children, adolescents, and adults with Tourette syndrome. Participants who completed a prior study may enroll and receive ecopipam for up to 24 weeks or longer. The main …

This study investigates the long-term safety and effectiveness of SPN-812 (viloxazine) in children and adolescents with ADHD. Participants who completed a prior SPN-812 study can continue taking the medication once daily for up to 72 months. The trial includes children aged 4–17 …

This study tests whether a mobile app can help parents of children aged 5-8 with disruptive behavior. 324 families will use either a standalone app, a coach-assisted app, or a control app. The goal is to see if digital tools can improve parenting skills and child behavior at a la…

This study tests whether choline, a vitamin-like nutrient, can improve memory, thinking, and behavior in children aged 2.5 to 5 years with Fetal Alcohol Spectrum Disorders (FASD). Participants receive choline daily for either 3 or 6 months. Researchers measure changes in memory, …

This study investigates whether combining the medication lovastatin with intensive reading tutoring can improve reading abilities in children and young adults (ages 8-20) with Neurofibromatosis Type 1 (NF1) who have reading disabilities. Participants first receive either lovastat…

This study tests a behavioral program called Individualized Developmental Care (NIDCAP) for newborns with complex congenital heart disease. The program aims to reduce stress from the hospital environment by supporting parent involvement, creating a soothing setting, and adjusting…

This study tests a program called REAL Fathers in Uganda, where respected community men mentor young fathers (ages 16-25) on positive parenting, conflict resolution, and family planning. Over 4,700 participants are involved. The goal is to see if this approach reduces intimate pa…

This study compares a new blended therapy (online sessions plus in-person visits) to standard in-person therapy for teens with conduct disorder or antisocial behavior. Researchers want to see if the blended approach works just as well at reducing aggression, delinquency, and out-…

This study was designed to see if hyperbaric oxygen therapy or computerized cognitive training could help adults with Fetal Alcohol Spectrum Disorder (FASD) think and function better. It planned to enroll 0 participants and was withdrawn before starting, so no results are availab…

This study tests whether a mix of treatments—including the patient's own stem cells, a strict keto diet, and a fecal transplant—can improve social skills, communication, and gut health in 50 teens and adults with autism. Participants must be stable on their current medications. T…

This study tests whether leucovorin calcium, a vitamin-like supplement, can improve language and other symptoms in young children with autism spectrum disorder. Researchers will enroll 80 children aged 2.5 to 5 years with language delays. The trial lasts about 26 weeks and compar…

This study aims to reduce disparities in ADHD care by adapting an evidence-based school program with mobile health technology. Researchers will test the digital tool with 350 participants, including students, parents, teachers, and school mental health providers in low-income and…

This study tests whether helping families with money and parenting skills can improve behavior in children ages 10-14 with oppositional defiant or conduct disorder. About 900 children and their caregivers in Uganda will be split into three groups: one gets financial help, one get…

This study tests a mobile health program called i-PregMom, which includes a smartphone app and digital food diary, to help pregnant women manage their blood sugar and weight gain. Researchers will enroll 160 first-time mothers and track their progress from early pregnancy (10-14 …

This study is testing a smartphone app called QbMobile that measures attention, impulsivity, activity, and movement patterns. Researchers want to see if it can provide objective data to help diagnose ADHD in people aged 6 to 60. The study includes 700 participants with and withou…

This study is testing a new AI-based system called AIMAS that aims to assess motor skills in children aged 6 to 12. The goal is to see if the AI can reliably identify kids with developmental coordination disorder (DCD) compared to standard clinical methods. Researchers will enrol…

This study is testing whether artificial intelligence can analyze a person's speech to help diagnose mental health conditions like depression, anxiety, autism, and schizophrenia. Researchers will record 500 people speaking and compare the AI's predictions to standard clinical dia…

This study is testing a new behavioral program for pregnant women with ADHD. The program teaches skills to manage ADHD symptoms during pregnancy and after the baby is born. Ten participants will work with a therapist in an OB care setting. The goal is to see if the program is acc…

This study explores whether a photography-based program can help children aged 8-12 with ADHD better recognize and express emotions, and improve attention and impulsivity. Sixty children will take photos and learn photography skills as a tool to boost emotional well-being. The go…

This study tests a communication coaching program for adolescent and young adult cancer survivors (ages 18-35) who have finished treatment at least a year ago. Participants complete online sessions and AI coaching to improve how they talk with peers. The goal is to see if the pro…

This trial tests a home-based program called the Sickle Cell Caregiver Collaboration for Child Development (SCCCD) for infants and toddlers with sickle cell disease. The program combines a parenting curriculum with occupational therapy to help families support their child's learn…

This study tests a 6-8 week running program adapted for children with mobility challenges like cerebral palsy. The program uses a special device called a RaceRunner to help kids participate. Researchers will measure endurance, speed, and heart rate to see if the program improves …

This study tests a digital tool that helps parents of young children with developmental delays or disabilities organize and share their priorities with early intervention professionals. The tool, called PEM+, is designed to make family-centered care more practical by guiding fami…

This study tests whether a 10-week internet-based cognitive behavioral therapy program can improve quality of life and reduce ADHD symptoms in adults. Two hundred adults in Sweden who have been diagnosed with ADHD and are working or studying will be randomly assigned to either th…

This study tests whether mild electrical stimulation of the ear, combined with physical and speech therapy, can improve symptoms like voice problems, swallowing, and balance in people with Parkinson's disease. 46 participants will receive either active or sham stimulation during …

This study follows children and adolescents with fetal alcohol spectrum disorder (FASD) who have already completed a dog-assisted therapy program. Researchers want to see if improvements in social skills, behavior, emotional well-being, and quality of life persist over 12 months.…

This study tests whether a community-based music mindfulness program can reduce anxiety and depression in children aged 8-12 with ADHD or anxiety. Participants attend bi-weekly sessions for 8 weeks, wear fitness trackers, and complete surveys. The goal is to see if this approach …

This study tests a drug called neflamapimod in 20 people with a language disorder called nonfluent variant primary progressive aphasia (nfvPPA). The goal is to see if the drug is safe and if it can improve language symptoms. Participants will receive either the drug or a placebo …

This study tests whether listening to special audio fairy tales before sleep can improve speech, motor skills, and independence in a child with autism and central auditory processing disorder. The child stays at home with their mother, avoiding clinic stress. Early results from t…

This study explores whether joining a weekly reading group can improve reading comprehension and communication confidence in adults with aphasia, a language disorder often caused by stroke. Participants read a book at home and then discuss it in a 90-minute group session each wee…

This study explores whether adding a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) to standard speech therapy can improve word-finding in people with aphasia after a stroke. The trial involves 50 adults who are at least six months …

This study explores whether high-intensity interval training (HIIT) is a practical and acceptable treatment for adults with ADHD. Researchers will recruit 30 adults diagnosed with ADHD to participate in a 14-week exercise program combining strength and endurance training. The goa…

This study compares two parent training programs for 3-5 year olds with sleep problems and early signs of ADHD. One program focuses on behavior, the other adds sleep strategies. Researchers want to see if the sleep-focused approach is more helpful and practical for families in pe…

This study tests a single online session that teaches a simple coping skill to youth ages 9-17 who are on a waitlist for therapy. The goal is to see if this quick digital tool can help ease symptoms of anxiety, depression, and stress while they wait. About 226 youth and their par…

This study tests a speech therapy method called Rapid Syllable Transition (ReST) in children aged 5 to 8 with childhood apraxia of speech, a condition that makes it hard to say sounds correctly. The goal is to see if the therapy is practical and helps improve speech clarity and m…

This study tests a therapy called RETELL that helps people with severe mental illness explore and reshape their life stories. The goal is to improve personal recovery, quality of life, and identity. Twenty adults with conditions like schizophrenia, bipolar disorder, or PTSD will …

This study tests a new program called PEAR that helps parents and teachers work together to manage ADHD and disruptive behavior in preschool children aged 2-5. The program adds extra support to a proven behavior tool called the Daily Report Card. Researchers want to see if PEAR i…

This study tests a remote speech therapy program for 32 Korean-speaking people with Parkinson's disease and their families. The therapy includes 16 sessions over four weeks, plus daily home practice, to improve speech clarity. The goal is to see if this culturally adapted approac…

This pilot study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can improve letter learning in 100 adolescents with dyslexia. Participants will learn new letter-sound relationships during six 30-minute sessions while receiving either ac…

This study tests a 12-session group program called Family Connections Transdiagnostic for relatives of people with emotional dysregulation disorders (like eating disorders or personality disorders). The program teaches skills in mindfulness, emotional regulation, and problem mana…

This study tests whether 80 sessions of a gentle brain stimulation technique called tDCS, given over 12 months, can improve attention, social skills, and language in 180 children aged 6 to 11 who have autism along with rare diseases, genetic problems, or PANDAS. The treatment is …

This study tests whether combining transcranial magnetic stimulation (TMS) with virtual reality exercises and physical therapy can improve symptoms like balance, fatigue, and thinking in people with multiple sclerosis. Thirty participants will receive both real and sham TMS in a …

This study looks at whether changing the sound of your own voice (like adding echo or whisper) can help adults who stutter speak more smoothly. About 100 people will use a special app for one month. The goal is to see if this simple technique improves fluency over time.

This study tests a communication tool called Best Case/Worst Case-ICU for older adults (50+) with serious injuries in the ICU. The tool helps doctors, patients, and families discuss possible outcomes and treatment options using simple graphics. Researchers will measure if it impr…

This study compares two fun approaches—creative movement (like dance and yoga) and play-based activities (like obstacle courses and building blocks)—to see which better improves motor skills, balance, and quality of life in children aged 5-8 with developmental delay. Twenty-eight…

This study tests a new medication (CTx-1301) for children aged 6 to 12 with ADHD. The goal is to see if it helps control symptoms like inattention and hyperactivity over a full school day. Children will take the drug or a placebo and be observed in a lab classroom for 14 hours. T…

This study tests whether a non-invasive device that gently stimulates the vagus nerve through the ear can improve speech recovery in people with aphasia after stroke or brain injury. Twelve adults with apraxia of speech will receive either active or sham stimulation during 16 wee…

This study planned to test whether a brain-computer interface (BCI) could help children with drug-resistant epilepsy improve their attention. Participants would have used brain electrodes already implanted for epilepsy surgery to train a decoder that gives real-time feedback when…

This study tests whether folinic acid (leucovorin), a drug already used to reduce side effects from chemotherapy, can improve language skills in children with autism spectrum disorder. Researchers will give the drug or a placebo to 56 children aged 5 to 17 for 12 to 24 weeks and …

This study tests an online self-help program called Together After Cancer for Latina breast cancer survivors and their intimate partners. The program includes brief coach calls and aims to improve the survivor's quality of life and the couple's relationship satisfaction. About 48…

This study aimed to see if a telehealth skills group could help middle and high school students with ADHD improve their organization, motivation, and grades. Both the treatment and control groups were delivered via Zoom. However, the study was withdrawn before enrolling any parti…

This study tests whether a specially designed group yoga program is practical and helpful for adults with ADHD symptoms. Twenty participants will be randomly assigned to either yoga or general movement classes. Researchers will track how many people join, stay, and complete the p…

This study tests a 6-week mobile app program for 60 teens aged 13–16 with ADHD. The app includes interactive exercises, animations, and weekly calls with a therapist to help with coping skills, healthy habits, and emotions. Teens and their parents fill out questionnaires before, …

This study tests whether the Apollo System, a device, can reduce ADHD symptoms in children aged 8 to 17. About 100 kids with diagnosed or suspected ADHD will use the device or a placebo version. Researchers will measure changes in attention and hyperactivity using parent surveys …

This study tests if a therapy called FIRST, which uses five key principles to help youth manage negative emotions, works better than standard therapy. About 212 youth aged 7 to 15 with anxiety, depression, trauma, or behavior problems will take part. The goal is to see if FIRST i…

This study tests whether a 16-session program called HOPS can help 6th to 8th graders with ADHD improve their organization, time management, and planning skills. Researchers are working with 240 students and their teachers in real school settings to see if the program works outsi…

This study tests a program called MSE-PEACE, where parents and children with developmental disabilities (like autism or ADHD) attend 10 sensory sessions together. The goal is to see if it improves children's engagement and emotional control, and helps parents feel more confident …

This study tests a digital health tool (CLS-D) that adapts an existing school-based behavioral program for students with ADHD. The goal is to make the program easier for schools with limited resources to use, especially those serving low-income families. About 216 students in 2nd…

This study tests whether a program of balance, coordination, and perception exercises can improve thinking, movement, and quality of life in 30 children with ADHD, ages 8 to 12. The training includes activities like balancing, shape perception, and eye-hand coordination. Research…

This small pilot study at Boston Children's Hospital will test whether a handheld device that guides deep breathing can help children with ADHD pay attention and control impulses. Ten children aged 7 to 11 will use the tool and then complete computer tasks while their brain activ…

This study tests whether watching immersive 360° videos of everyday actions can improve word-finding in people with anomic aphasia after a stroke. Forty participants will either watch first-person 360° videos or standard third-person videos over 12 sessions. The goal is to see if…

This study tests whether a mild electrical current applied to the brain (tDCS) during speech therapy can improve language recovery in people with aphasia after a stroke. Two hundred adults with language problems from left-brain damage will receive either real or fake stimulation …

This study tests an experimental drug called gemlapodect to see if it can safely reduce tics in people with Tourette syndrome. About 164 adults and teens with moderate to severe tics will take the drug or a placebo for 12 weeks. The main goal is to measure changes in tic severity…

This pilot study aimed to test a parent-only training program for children aged 8-12 with both ADHD and overweight or obesity. Parents would learn weight management skills and strategies to help their child's focus and planning. However, the study was withdrawn before any partici…

This study tests whether taking postbiotics (beneficial bacteria byproducts) can improve ADHD symptoms like mood and sleep in children aged 6-13. Eighty participants will take two capsules daily for 8 weeks, with a 4-week follow-up. Researchers will track symptom changes using pa…

This study compares virtual reality-supported speech therapy to traditional speech therapy in 100 children aged 3 to 6 with developmental language disorder. Each child receives the same amount of therapy, but one group uses a VR system with touchscreen exercises while the other u…

This study tests whether virtual reality games can improve executive functions—like memory, focus, and planning—in 50 youth aged 8 to 18 with autism and ADHD. Participants will either play VR cognitive games or receive standard care. Researchers will compare thinking skills befor…

This study looks at whether unlicensed professionals can successfully provide cognitive behavioral therapy (CBT) to patients in a general hospital. It includes 250 adults with conditions like anxiety, depression, OCD, and PTSD. The goal is to see if this approach improves psychol…

This study tests whether a non-invasive device called tRNS can safely reduce ADHD symptoms in children aged 7 to 12 who are not on medication. Over 10 sessions in two weeks, kids receive either real or sham stimulation while playing a computer game. Researchers track symptom chan…

This small study looks at whether morning flashed light therapy, combined with online sleep counseling, is acceptable and tolerable for teens aged 14-17 with ADHD and delayed sleep. Six participants will try the light therapy daily for six weeks and attend weekly video sessions. …

This study tests whether giving both caregivers and teachers a resource package for managing hyperactive, inattentive, or impulsive behaviors helps children more than giving it only to teachers. About 100 children in grades K-5 will take part, and researchers will measure how fea…

This study aimed to see if combining biofeedback, breathing exercises, nutrition counseling, and exercise could help children and teens aged 7-18 with ADHD. Participants would have learned to control body functions like heart rate and practiced relaxation techniques, while also g…

This study tests a parent training program called the New Forest Parenting Programme for children aged 3-12 who have ADHD or trouble with attention and activity. Researchers want to see if it is practical and acceptable for families in Danish community clinics. The study includes…

This study tests a 22-week small-group program called Let's Know!2 for first graders with low language skills. The program uses fun lessons to build vocabulary and comprehension. Researchers will compare children who get the program to those who don't, tracking their progress thr…

This pilot study tests a telehealth-delivered training program for caregivers of infants (12-18 months old) who show early signs of ADHD, such as trouble with self-control or emotion regulation. The program teaches caregivers strategies to support their child's development throug…

This study looks at whether a set of thinking and memory tests can detect changes caused by a stimulant medication in children aged 6 to 17 who have both intellectual disability and ADHD. About 68 participants will receive either the medication or a placebo, then switch after a b…

This study tests whether neurofeedback—a non-invasive brain training technique—can reduce symptoms of attention deficit hyperactivity disorder (ADHD) in teenagers. Researchers in Tanta, Egypt, are enrolling 40 participants aged 12 to 18. The approach uses real-time brain activity…

This study tests whether a mild electrical current applied to the scalp (tDCS) can boost attention and working memory in adults with ADHD. Researchers will vary the strength and duration of the stimulation to find the best dose. 104 participants will complete attention tasks whil…

This study tests two types of speech therapy for people with primary progressive aphasia, a brain disorder that slowly destroys language skills. Sixty participants will work on word retrieval or script practice with a clinician and at home. Researchers will measure changes in com…

This study tests a speech-language telerehabilitation program for people with primary progressive aphasia (PPA), a dementia that slowly destroys language abilities. The program includes online therapy sessions and care partner training. Researchers will enroll 21 participants to …

This study was designed to test whether ADZENYS XR-ODT, a once-daily amphetamine tablet that dissolves in the mouth, could help manage ADHD symptoms in children aged 4 to less than 6 years. The trial was planned as a randomized, double-blind, placebo-controlled study, but it was …

This study tests whether adding in-home decluttering sessions to group cognitive-behavioral therapy can reduce hoarding severity in adults with hoarding disorder. About 90 participants in Sweden will receive 10 weekly home visits focused on guided decluttering, alongside standard…

This study tests whether a non-invasive brain stimulation technique called iTBS can improve attention and self-control in children aged 6 to 12 with ADHD. Over two weeks, 40 children will receive either real or sham stimulation, and researchers will measure changes in attention u…

This study tests a training program that teaches children with physical disabilities how to use their manual wheelchairs better. The goal is to help them move around on their own instead of relying on others, which can improve their confidence and social life. Four children aged …

This study tests whether a non-invasive brain stimulation technique called iTBS can improve ADHD symptoms in teenagers. For 10 days, participants receive magnetic pulses to a brain area linked to attention and memory. Researchers will measure changes in brain activity, working me…

This completed study tested different messages to see which ones make adults more willing to get the HPV vaccine, which prevents certain cancers. Over 5,300 adults aged 18-45 were randomly assigned to read one of five theory-based messages or a control message. The goal was to fi…

This study uses MRI scans to look at the brains of children and adults with conditions like ADHD, autism, schizophrenia, and endocrine disorders, as well as healthy volunteers. Researchers aim to compare brain anatomy and function across different groups and ages. The goal is to …

Researchers are investigating whether brain connectivity and blood markers differ between adolescents with ADHD and healthy teens. The study includes 40 teens with ADHD and 40 matched controls, aged 10 to 18. Participants undergo brain imaging, blood tests, and assessments of exe…

This study tests a program called Preschool and Me (PreM) that helps families of children with developmental delays or disabilities connect with school-based services. The program uses a care plan and a navigator to guide families through the process. Researchers hope this will i…

This study follows children from kindergarten through first grade to understand how brain networks involved in reading, math, and executive function (thinking skills like attention and planning) interact to predict academic outcomes. Researchers will also see if these brain and c…

This study tests whether coaching or communication classes for primary care clinicians can improve patient satisfaction scores and reduce clinician burnout. About 45 Mayo Clinic providers will take part, filling out questionnaires before, right after, and two months after the tra…

This study looks at how people use their sense of hearing versus physical feeling when they speak. Healthy adults aged 18 to 45 will do speech tasks with altered audio feedback, sometimes with a visual display. Researchers will use a computer model to see if individual difference…

This study looks at whether genes and thinking skills like memory can predict how well someone with aphasia (trouble speaking after a stroke) responds to word-retrieval therapy. Researchers will work with 120 people who had a stroke at least six months ago. The goal is to move to…

This study explores whether wearable smartwatches can objectively measure activity levels in children with attention-deficit hyperactivity disorder (ADHD). Researchers plan to compare activity data from 50 children with ADHD and 50 neurotypical children over a one-month period. T…

This study follows children aged 6 to 21 who have a CNKSR2 gene mutation, which can cause epilepsy, language difficulties, and intellectual disability. Researchers will use brain scans, EEGs, and developmental tests to track how the condition changes over time. The goal is to cre…

This study tests a program that helps parents and teens work together to improve safe driving. It includes 588 teens aged 16-17 who have already received a traffic ticket. The program uses a smartphone app and in-car device to track risky driving and give feedback, aiming to redu…

This study investigates how the brain suddenly stops speech that is already underway. Researchers will record brain activity from epilepsy patients who already have electrodes implanted for medical reasons, as they perform speech tasks. The goal is to identify the neural circuits…

This study tests a computer-based word retrieval practice for people with aphasia, a language disorder often caused by stroke. Twenty adults who have trouble finding words will practice naming pictures with feedback. The goal is to see if this practice can improve word retrieval …

This study investigates how the brain processes speech sounds to understand language. Researchers will record brain activity from people with epilepsy or brain tumors who already have electrodes implanted for medical reasons. Participants listen to short speech sounds while their…

This study was designed to see if cognitive behavioral therapy for insomnia (CBT-I) could help teenagers with ADHD who also have trouble sleeping. It planned to enroll adolescents aged 11-18 with both ADHD and insomnia. However, the trial was withdrawn before any participants wer…

This study trains police officers and first responders to better communicate with people who have aphasia, a condition that affects speech and understanding. 75 participants from the Madison Police Department will take part for up to 6 months. The goal is to see if training impro…

This study aimed to see if monthly video calls could help track swallowing issues in people who had intensive rehab after throat cancer treatment. It planned to enroll adults with chronic swallowing problems and check if they could attend at least 3 out of 5 remote sessions. Howe…

This study compares 6 months of group music activities versus circus activities in 200 infants (8-12 months old) with or without a family history of dyslexia. Researchers will measure language skills, brain responses to sounds, and social-emotional factors. The goal is to see if …

This study compares two methods of training surgeons to have better conversations with patients about surgery risks and goals. About 60 surgeons and 660 patients will take part. One group of surgeons gets training from an education specialist, the other from a computer program. T…

This study tests whether a digital tool called QbMobile can accurately measure changes in ADHD symptoms after starting treatment. Researchers will enroll 175 people aged 6 to 60 who are newly diagnosed or not yet on medication. Participants use QbMobile to generate a symptom scor…

This study investigates how the brain determines what's important to look at, balancing things that stand out (like bright colors) with things we know are relevant. Researchers will have 240 healthy adults perform visual tasks while measuring their response times and eye movement…

This study was designed to test whether scheduled video calls with a nurse could help family members who make medical decisions for hospitalized older adults with Alzheimer's or similar cognitive issues. The goal was to improve communication and reduce anxiety and depression. How…

This study looks at whether a special health check-up for older adults (called a geriatric assessment) can help them and their caregivers talk more effectively with their doctors about age-related concerns. About 479 older cancer patients and their caregivers are taking part. The…

This study tests whether a structured educational program can improve primary school teachers' knowledge and classroom skills for managing students with ADHD. 175 teachers who have at least one student with a confirmed ADHD diagnosis will take part. The program covers ADHD basics…

This study watches a single gynecology resident as they learn to perform a hysterectomy through the vagina using a special camera, leaving no belly scars. The goal is to see how quickly the resident improves, measuring surgery time and any complications. Nineteen women with benig…

This study looks at a care approach called a time-limited trial (TLT) for ICU patients who need a breathing machine. Doctors, patients, and families agree to try treatments for a set time, then check if the patient is recovering. The goal is to see if this approach can reduce ICU…

This study looks at how eye movements, specifically eye vergence (how eyes work together for depth perception), relate to attention in people with ADHD and autism. Researchers will use computer-based eye-tracking tasks with 200 children and adults to see if these eye patterns can…

This study planned to use high-frequency brain signals to locate important brain areas and understand conditions like epilepsy, migraine, and ADHD. It aimed to create a large database of brain activity in people aged 1 day to 69 years. However, the study was withdrawn before any …

This study looks at how genes might be linked to behavior in 200 children aged 7-16 with disruptive behavior disorders like Conduct Disorder or Oppositional Defiant Disorder. Some of these children also have callous-unemotional traits, such as lack of guilt or shallow emotions. R…

Researchers at Arkansas Children's Hospital are studying how mitochondria work in children with autism spectrum disorder. They aim to identify distinct patterns of mitochondrial dysfunction that may relate to developmental delays. The study involves up to 5 visits with blood draw…

This study aims to understand why many people with Tourette syndrome are overly sensitive to everyday sensations like touch or noise. Researchers will monitor brain activity, heart rate, and sweat responses in 50 adults with Tourette syndrome while they experience different sound…

This study tests a new behavioral therapy designed to help veterans with traumatic brain injury (TBI) improve their storytelling and everyday communication. The therapy focuses on both story content and organization. The trial includes 34 veterans and aims to see if the treatment…

This study looks at how the brain's temporal lobe helps process sound. Researchers will measure brain activity using EEG in 10 people who have had surgery to remove a lesion in a key hearing area. The goal is to better understand how the brain generates electrical responses to sp…

This study looks at whether taking common painkillers like paracetamol or ibuprofen during pregnancy can affect a child's brain development, behavior, and language skills. Researchers will follow 685 children aged 2 to 4 years whose mothers were part of an earlier study on painki…

This study tests a new interactive multimedia program designed to teach ICU nurses about chemotherapy drug administration. Fifty nurses at a medical center in southern Taiwan will use the system for about 30 minutes and complete tests before and after to see if their knowledge an…

This study aims to learn more about diseases that affect the brain, such as Parkinson's disease and different types of dementia. Researchers will follow 500 adults with symptoms of these conditions over time, using brain scans and genetic tests to see how the diseases progress. T…

This study looks at whether a special fraction teaching program helps 4th-grade students, including those with math learning difficulties, improve their fraction skills. About 2,210 students will take part, with some teachers using the program and others teaching normally. The go…

This study looks at how the cerebellum, a part of the brain, helps us learn and adjust our speech. Researchers will use brain scans, magnetic stimulation, and speaking tasks in people with cerebellar ataxia (a movement disorder) and healthy volunteers. The goal is to better under…

This research studies a program that places social workers in 25 children's doctor offices across Indiana. The goal is to help doctors spot and treat mental health issues like depression and anxiety sooner. About 575 patients and staff will take part to see if this approach impro…

This study looks at a special training program called Fundamentals of Communication in Surgery (FCS) for surgeons and surgery trainees. The goal is to see if the training helps surgeons communicate better with patients and each other. About 600 people will take part, and research…

This study tests whether artificial intelligence can improve how emergency call operators recognize strokes. Researchers will analyze 1,000 emergency calls to see if AI can detect signs of stroke more accurately than current methods. The goal is to help stroke patients get to the…

This study records brain activity from people with epilepsy or brain tumors who already have electrodes implanted for medical reasons. Participants listen to short speech sounds in English, Spanish, or Mandarin while their brain signals are measured. The goal is to understand how…

This study looks at whether a power wheelchair that can lift a child from sitting to standing is practical for kids with conditions like cerebral palsy, spinal cord injuries, or genetic diseases. Only 4 children aged 5-17 are taking part. The goal is to see if the chair helps the…

This study tests a computer program called GraphoLearn, designed to improve reading skills in children aged 6 to 10 with reading disabilities. Researchers will compare reading gains in children who use GraphoLearn versus those who use a math program. The goal is to see if the app…