Brain zaps and VR games: a new hope for MS symptoms?

NCT ID NCT07593807

Ongoing Symptom relief Sponsor: University of Sao Paulo Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether combining transcranial magnetic stimulation (TMS) with virtual reality exercises and physical therapy can improve symptoms like balance, fatigue, and thinking in people with multiple sclerosis. Thirty participants will receive both real and sham TMS in a crossover design, with outcomes measured over a year. The goal is to see if this non-drug approach can ease multiple MS-related problems at once.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: transcranial magnetic stimulation (TMS)
What this could lead to: If it works, this could point toward a non-drug way to ease multiple symptoms of MS, like fatigue, balance problems, and brain fog.
What could go wrong: This is a small, early-stage trial with only 30 people, so results may not apply to everyone. The treatment is also complex and time-consuming, which might limit real-world use.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

communication disorder Depression multiple sclerosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE SCLEROSIS

Contacts and locations

Locations

ABEM - Associação Brasileira de Esclerose Múltipla

São Paulo, São Paulo, Brazil

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