Can the right words boost HPV vaccination? new study tests message strategies

NCT ID NCT06784960

Completed Knowledge-focused Sponsor: Abramson Cancer Center at Penn Medicine Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This completed study tested different messages to see which ones make adults more willing to get the HPV vaccine, which prevents certain cancers. Over 5,300 adults aged 18-45 were randomly assigned to read one of five theory-based messages or a control message. The goal was to find the most effective communication strategies to increase vaccination intentions.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could point toward more effective ways to talk about the HPV vaccine, helping more adults choose to get vaccinated.
What could go wrong: This is a survey experiment, not a real-world vaccination campaign. People's stated intentions may not match actual behavior, and the messages may not work in all communities.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Communication communication disorder Vaccination Hesitancy human papilloma virus infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

COMMUNICATION PAPILLOMA VIRAL INFECTION VACCINE HESITANCY

Contacts and locations

Locations

University of Pennsylvania

Philadelphia, Pennsylvania, 19104, United States

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