Gene hunt: could DNA explain tough behavior in kids?

NCT ID NCT07322055

Ongoing Knowledge-focused Sponsor: IRCCS Fondazione Stella Maris Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how genes might be linked to behavior in 200 children aged 7-16 with disruptive behavior disorders like Conduct Disorder or Oppositional Defiant Disorder. Some of these children also have callous-unemotional traits, such as lack of guilt or shallow emotions. Researchers will compare genetic profiles with clinical data to better understand why some children develop more severe symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this research could help identify genetic factors that influence behavior, potentially leading to better risk assessment and personalized support for children with disruptive behavior disorders.
What could go wrong: This is an observational study, not a treatment trial. It only looks for correlations, so it cannot prove cause and effect. The findings may not apply to other ethnic groups or ages.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

conduct disorder oppositional defiant disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CALLOUS-UNEMOTIONAL TRAITS CONDUCT DISORDER OPPOSITIONAL DEFIANT DISORDER

Contacts and locations

Locations

IRCCS Fondazione Stella Maris

Pisa, Pisa, 56128, Italy
Università di Pisa

Pisa, Pisa, 56126, Italy

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