New study aims to find best therapy for angry outbursts in kids

NCT ID NCT07640802

First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 3 times

Summary

This study compares three types of therapy for children aged 8 to 16.5 with severe irritability. Participants will receive either exposure-based cognitive behavioral therapy, parent management training, or supportive psychoeducation over 12 sessions. The goal is to see which approach best reduces temper outbursts and irritable mood. The trial involves 300 youth and their parents and includes follow-up for one year after treatment.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

psychotherapy (exposure-based cognitive behavioral therapy, parent management training, or psychoeducation supportive psychotherapy)

What this could lead to

If successful, this could identify a specific therapy that effectively reduces severe irritability in children, providing a targeted treatment option.

What could go wrong

This is a relatively early-stage trial with no results yet. The therapies may not differ significantly in effectiveness, and individual responses can vary. The study is not yet recruiting.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

attention deficit hyperactivity disorder, inattentive type attention deficit-hyperactivity disorder oppositional defiant disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••