IRRITABILITY
Clinical trials for IRRITABILITY explained in plain language.
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New hope for chronically cranky kids: therapy trial targets severe temper outbursts
Symptom relief Recruiting nowThis study tests two psychological treatments—Cognitive Behavioral Therapy (CBT) and Interpretation Bias Training (IBT)—for children aged 8 to 17 with severe irritability and temper outbursts, a condition called Disruptive Mood Dysregulation Disorder (DMDD). Participants will rec…
Matched conditions: IRRITABILITY
Sponsor: National Institute of Mental Health (NIMH) • Aim: Symptom relief
Last updated Jul 02, 2026 00:00 UTC
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AI coach for parents: could an app tame tantrums?
Symptom relief Recruiting nowThis study tests whether adding an AI app to standard behavioral parent training helps families with children aged 5-12 who have disruptive behaviors like irritability or ADHD. Forty parents will either attend 8 weekly online training sessions alone or with 24/7 access to an AI v…
Matched conditions: IRRITABILITY
Phase: NA • Sponsor: Fundació Sant Joan de Déu • Aim: Symptom relief
Last updated Jun 27, 2026 11:00 UTC
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Scientists scan brains to unlock the mystery of frustration
Knowledge-focused Recruiting nowThis study aims to understand how the brain responds to frustration in healthy adults aged 18 to 55. Participants will undergo brain scans (MRI and MEG) while performing a task that may cause frustration. The goal is to identify brain activity patterns linked to frustration, whic…
Matched conditions: IRRITABILITY
Phase: EARLY_PHASE1 • Sponsor: National Institute of Mental Health (NIMH) • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:24 UTC
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Brain scans may reveal which kids with ADHD benefit from stimulants
Knowledge-focused Recruiting nowThis study involves 136 children with ADHD who also have high levels of irritability or aggression. Researchers will measure tiny brain signals (called ERPs) while children do tasks, then see if those signals can predict which kids get the most benefit from stimulant medication. …
Matched conditions: IRRITABILITY
Phase: PHASE4 • Sponsor: Milton S. Hershey Medical Center • Aim: Knowledge-focused
Last updated Jun 27, 2026 12:10 UTC
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Antidepressant study probes anger processing in healthy youth
Knowledge-focused Recruiting nowThis study at the University of Oxford is testing how the antidepressant fluoxetine (Prozac) influences the way healthy young people process anger. Eighty participants aged 18-24 will take either fluoxetine or a placebo for 7 days and complete tasks involving angry faces, words, …
Matched conditions: IRRITABILITY
Phase: NA • Sponsor: University of Oxford • Aim: Knowledge-focused
Last updated Jun 27, 2026 09:07 UTC