Scientists scan brains to unlock the mystery of frustration
NCT ID NCT06484088
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study aims to understand how the brain responds to frustration in healthy adults aged 18 to 55. Participants will undergo brain scans (MRI and MEG) while performing a task that may cause frustration. The goal is to identify brain activity patterns linked to frustration, which could eventually help develop better treatments for irritability.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
What this could lead to
If successful, this study could reveal brain patterns linked to frustration, pointing toward new targets for treating irritability.
What could go wrong
This is an early-phase observational study in healthy adults, not a treatment trial. Results may not apply to people with clinical irritability.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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National Institutes of Health Clinical Center
RECRUITINGBethesda, Maryland, 20892, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Texas A&M University
NOT_YET_RECRUITINGCollege Station, Texas, 77843, United States
Contact Phone: •••-•••-••••