Magnetic pulses to the brain may calm irritability

NCT ID NCT07678060

Ongoing Symptom relief Sponsor: Yale University Source: ClinicalTrials.gov ↗

First seen Jul 01, 2026 · Last updated Jul 02, 2026 · Updated 1 time

Summary

This study tests whether a noninvasive technique called repetitive transcranial magnetic stimulation (rTMS) can reduce irritability by targeting brain circuits involved in frustration. About 20 adults with elevated irritability will receive rTMS while researchers measure brain activity, grip force, and self-reported frustration. The goal is to see if this approach can safely ease irritability symptoms.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: repetitive transcranial magnetic stimulation (rTMS)
What this could lead to: If it works, this could point toward a noninvasive brain stimulation treatment for irritability in people with mental health conditions.
What could go wrong: This is a small pilot study with only 20 participants, so results may not apply broadly. The treatment is experimental and may not reduce irritability as hoped.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

Psychological Well-Being

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IRRITABILITY MENTAL HEALTH

Contacts and locations

Locations

Hartford Healthcare

Hartford, Connecticut, 06102, United States

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Other studies related to the condition(s) this trial covers.