MENTAL HEALTH

This study tests whether taking a daily multivitamin for 12 months can improve metabolic health, mental well-being, and muscle strength in midlife Asian women aged 40-60. Researchers will measure a 'MetaboAge' score to see if supplements slow metabolic aging. The goal is to find …

This study tests two programs for people recently in jail or under supervision. One offers health navigation; the other adds employment help and small financial incentives. The goal is to see which better helps participants access HIV care, prevention, and jobs. About 350 Black m…

This study tests whether a group therapy for PTSD, adapted for prisons, can help people reduce drug use, mental health issues, and crime after they leave prison. About 640 incarcerated adults across 10 US prisons will either receive the group therapy or a self-help workbook. Rese…

This study tests a 9-month program called NE+ for American Indian youth ages 12-18. The program includes educational modules, cultural teachings, and caregiver involvement to promote healthy relationships, prevent substance use, and improve mental health. Researchers will compare…

This study tests whether a program that provides farming tools, training, and family support can reduce sexually transmitted infections (STIs) and improve mental health in 900 teen girls (ages 15-19) in Kenya. The program aims to reduce food insecurity and poverty, which are link…

This study is testing a new method to train teachers in Uganda to support their own mental health and that of their students. The program, called mWEL-PD, teaches teachers simple, proven strategies to create a positive classroom environment and engage with parents. The study will…

This study tests a digital program called Family Check-Up Online, designed to help parents improve their child's mental health and prevent family violence. About 1,270 families with children aged 11-14 will take part. Parents will use the program on their smartphone, with some ge…

This study looks at gambling habits in 16-25-year-olds after COVID-19 and tests a digital escape room game designed to prevent gambling in high school students. About 240 students aged 16-18 will take part. The goal is to see if the game can reduce teens' interest in gambling and…

This study looks at whether a 16-week program combining mindfulness meditation and Nordic walking-pole exercise can help older adults feel better physically and mentally. About 1,500 people aged 55 and older will take part. Researchers will measure changes in strength, mood, slee…

This study tests whether an 8-week mindfulness program (MBCT-L) can improve the mental health and teaching skills of 160 school teachers in Hong Kong. Teachers will learn meditation and awareness techniques to reduce stress and anxiety, and researchers will measure changes in the…

This study tests whether an online self-help platform called JCTH+ can improve mental health for university students in Hong Kong. About 1,684 students with moderate to severe anxiety or depression will use the platform alongside usual services. The goal is to see if the platform…

This study compares two programs for Veterans with mental health and relationship issues: a 3-session couple-based program (Brief Relationship Checkup) and standard individual care. The goal is to see which better reduces suicide risk factors by improving relationship health. Abo…

This study tests a friendly AI chatbot that guides people through telling their life stories to boost emotional well-being. It includes healthy adults, older adults aged 65+, and adults with mental health conditions living in care homes. The chatbot helps create a personal "life …

This study tests whether adding a special supplement to a mindfulness program helps college students aged 18-25 feel less stressed, anxious, or depressed. About 120 students with high stress will join one of three groups: mindfulness only, mindfulness plus supplement, or a health…

This study tests if an 8-week virtual mindfulness program (MBSR) can reduce fatigue in people with sarcoidosis. 100 participants will either join the MBSR program or a monthly virtual support group. The goal is to see which approach better improves fatigue, anxiety, and depressio…

This study tests whether regular, friendly phone calls can improve mental health and reduce loneliness in older adults who are homebound. About 400 people aged 65 and older who receive home services will be assigned to one of two types of supportive phone calls or a control group…

This study is testing a structured psychological program to help teenagers (ages 10-19) with scoliosis manage anxiety, pain, and depression before and after spinal fusion surgery. The program is based on cognitive behavioral therapy (CBT) and is designed to reduce distress. Resea…

This study looks at whether intermittent fasting (the 16/8 method, where you eat only during an 8-hour window each day) can improve the mental health of women going through perimenopause. About 140 women aged 45-55 will be randomly assigned to either follow this eating pattern or…

This study tests a mobile app called Stappvoorstap for adults on mental health waiting lists in the Netherlands. Over 4 weeks, participants use the app to track stress, learn coping skills, and access relaxation exercises. The goal is to see if the app can reduce stress and impro…

This study looks at whether a short mindfulness program (15-20 minutes, 3 times a week for 8 weeks) can improve basketball skills, body movement, and mental well-being in university basketball players. About 126 athletes from three Macau universities will take part. Researchers w…

This study tests a contemplative practice called Feeding Your Demons (FYD), adapted from Tibetan Buddhism, to see if it helps women feel better mentally and about their bodies. About 122 adult women who already meditate will be randomly assigned to FYD or standard mindfulness med…

This study tests whether a 12-week digital yoga program called MediYoga can improve quality of life, lower blood pressure, and reduce heart rate in 456 adults with paroxysmal atrial fibrillation. Participants use a smartphone app and get online support. The goal is to see if this…

This study tests a program called Mentis Plus+ Caregivers to see if it improves positive mental health in adults who care for a family member with dementia. About 108 caregivers will either join the program or receive usual care. The goal is to help caregivers feel better and red…

This study looks at whether eating nuts can help reduce symptoms of depression, anxiety, and stress in young adults aged 18 to 25. Researchers will also measure memory, thinking skills, and a brain-related protein called BDNF. A total of 135 university students will be randomly a…

This study tests whether a culturally adapted skills training program called START NOW can reduce depression and anxiety in adolescent refugees aged 14 to 18. About 80 participants will be randomly assigned to either the START NOW program or standard care. The goal is to see if t…

This study tests a virtual health coaching program for adults with type 2 diabetes and mental health challenges. Participants receive weekly coaching calls, support from a care team, and online tools. The goal is to see if this approach improves quality of life compared to usual …

This study tests a text message program for first-time parents in Nova Scotia. For 6 weeks after birth, parents receive texts with tips on baby care and coping. Researchers want to see if this boosts confidence and lowers anxiety, depression, and stress. About 332 parents will be…

This study is testing a community-based program called Mental Health CPR to see if it helps improve emotional well-being and access to mental health services for Hispanic/Latino cancer survivors in Puerto Rico. Researchers will compare the program to standard health education to …

This study tests whether a 10-session parenting program called Attachment and Biobehavioral Catch-up (ABC) can lower stress-related biomarkers in children aged 2 to 3 who have experienced early life adversity. About 150 caregiver-child pairs will be randomly assigned to receive t…

This observational study aims to define a new concept called 'visual frailty' in people aged 60 and older with advanced age-related macular degeneration (AMD). Researchers will measure vision, reading ability, mental health, and daily function to see how these factors relate. The…

This study aims to understand how the COVID-19 pandemic has affected the mental, physical, and social well-being of minority women and their families in North Carolina. Researchers will survey 700 healthy women aged 18 and older, and may collect blood, urine, saliva, toenail, dus…

This study looks at whether a tool called PRPP (Perceive, Recall, Plan and Perform) can help doctors and therapists decide the best support for older adults with psychiatric disorders who live on their own. As people with these conditions age, they often struggle with memory, att…

This study tests a digital program called eBASIS that helps school mental health providers use evidence-based treatments more effectively. Researchers will compare providers who use eBASIS to those who don't, measuring how well they stick to the program and how their students do.…

This study looks at whether specially trained doulas can help pregnant people in rural Montana feel more confident and supported, and reduce symptoms of depression and anxiety after childbirth. About 75 participants will be split into three groups: one gets regular doula care, on…

This study follows 300 young men who have sex with men (ages 18-24) living with HIV in Ho Chi Minh City, Vietnam, for 12 months. Researchers will track how well they are doing on their HIV medication, their viral suppression, mental health, and quality of life. The goal is to und…

This study tests whether teaching married couples about money management and healthy relationships can strengthen their bond and improve mental health. About 4,500 people in India will take part, with some couples receiving the program and others not. Researchers will measure cha…

This study talks to men who have sex with men and take part in chemsex (using drugs during sex) in Bangkok. Researchers want to learn about the risks, health problems, and needs of these men. The goal is to create a program where party hosts help reduce harm, like preventing HIV …

This study looks at whether a 6-session program can help parents of children with disabilities feel more confident and work better together when getting school and health services. About 120 parents will take part before their child's first Individualized Education Program (IEP) …

This study tests whether a device called Neuphoria, used with Monroe's EEG neurofeedback, can improve mental clarity and well-being. Researchers will measure brain activity, stress levels, and mindfulness in 100 adults. The goal is to understand how the brain responds to this tra…

This study looks at whether adding conversations about sexual pleasure to existing harm reduction services helps men who have sex with men and transgender people who use drugs during sex. Researchers will use a tool called the Pleasuremeter to measure sexual pleasure and see how …

This study tests a new program called Project YES+ for youth aged 15-21 living with HIV in Zambia. The program combines peer mentoring with a mental health approach endorsed by the World Health Organization to reduce stigma related to HIV, violence, and mental health. Researchers…

This study is developing and testing a small-group program called THRiVE for veterans who left the military within the last year. The program is led by peers and focuses on improving mental health and reducing suicide risk. Up to 40 veterans will take part in the program and comp…

This study is developing and testing a web-based tool to help state decision-makers choose the best evidence-based programs to support parent and child mental health. About 80 adults involved in state-level decisions will use the tool and provide feedback. The goal is to see if t…

This study tests a program called FRAME that helps heart failure patients discuss mental health with their doctors and loved ones. About 7,300 adults with heart failure or at risk for it will take part in clinics across Ontario, Canada. The goal is to see if the program is practi…

This research study looks at how myelin, the insulation around nerve fibers, influences thinking skills in people aged 10 to 25. Participants will have an MRI scan and complete thinking tasks to measure memory, planning, and decision-making. The goal is to understand normal brain…

This study follows up with people who had a life-threatening heart rhythm problem called electrical storm and were treated in the ICU. Researchers want to understand how the experience and treatments affect mental health and quality of life months later. Participants fill out que…

This study compares two web-based apps to see which one better helps Latinas with anxiety or depression start mental health treatment. One app uses an interactive story with a character who gives treatment advice, while the other provides standard information and resources. The g…

This study tests a training program called First Face for Mental Health in seven Tribal Nations. About 1,000 community members aged 14 and older will take part. Half get the training right away, the other half wait six months. Researchers will compare surveys to see if the traini…

This study is testing a program called Level Up, which teaches life skills to soldiers arriving at their first duty location. The program is delivered through a mobile app and includes personalized messages and virtual booster sessions. Researchers want to see if it can reduce ha…

This study tests whether a digital dashboard can help home visitors in Rwanda deliver mental health support more effectively. The program, called Sugira Muryango, aims to improve family well-being and reduce violence. About 1,800 caregivers and officials will take part to see if …

This study aims to understand how the recent war in Israel has impacted the mental and physical health of children and adolescents, and what makes their therapy successful or leads to dropping out. Researchers will analyze data from 30,000 young people in therapy, looking at fact…

This study looks at whether giving parents of children with chronic conditions a mental health questionnaire during clinic visits can help identify stress, anxiety, or depression. About 100 parents will fill out the survey, get their results, and receive a list of support service…

This study tests whether adding 8 weeks of mindfulness training to a single dose of psilocybin (the active ingredient in magic mushrooms) improves mental health more than psilocybin alone. Forty healthy adults aged 25 and older who have never used psychedelics or done formal mind…

This study is testing whether 'Hope Groups' — a support program that combines mental health help, parenting tips, and violence prevention — can improve the well-being of Palestinian caregivers displaced by war. About 490 parents or caregivers living in refugee camps will take par…

This study tests whether a website called SolanoConnex.org helps people with mild to moderate mental health symptoms take steps to get support. About 200 adults in Solano County, California, will be randomly assigned to use the website or receive standard public resources. Resear…

This study partners with community organizations and trusted local members to improve health research participation among Black, Latino, and Native American communities in Colorado. It focuses on understanding and addressing health issues like mental health, high blood pressure, …